B Lymphocyte Chemoattractant Simoa (BLC Simoa)

B Lymphocyte Chemoattractant (BLC, CXCL13) is a chemokine that, through its interaction with the receptor CXCR5, is a chemoattractant for B lymphocytes. BLC controls the organization of B cells within follicles of lymphoid tissues. It is secreted by dendritic cells, and is expressed highly in the liver, spleen, lymph nodes, and gut of humans.

Swiss-Prot Accession Number: O43927

Product Associations Product Associations

This analyte is not currently part of Myriad RBM's testing menu.

Myriad RBM Publications Publications
Efficacy and safety of abatacept in active primary Sjögren's syndrome: results of a phase III, randomised, placebo-controlled trial (2020) Baer AN, Gottenberg JE, St Clair EW, Sumida T, Takeuchi T, Seror R, Foulks G, Nys M, Mukherjee S, Wong R, Ray N, Boothsma H Annals of the Rheumatic Disease
Spebrutinib (CC-292) Affects Markers of B Cell Activation, Chemotaxis, and Osteoclasts in Patients with Rheumatoid Arthritis: Results from a Mechanistic Study. (2019) Schafer PH, Kivitz AJ, Ma J, Korish S, Sutherland D, Li L, Azaryan A, Kosek J, Adams M, Capone L, Hur EM, Hough DR, Ringheim GE Rheumatology and Therapy