Rules-Based Medicine Bibliography
Bibliography
2022
T cell apoptosis characterizes severe Covid-19 disease (2022) Andre S, Picard M, Cezar R, Roux-Dalvai F, Alleaume-Butauz A, Soundaramourty C, Santa Cruz A, Mendes-Frias A, Gotti C, Leclercq M, Nicolas A, Tauzin A, Carvalho A, Capela c, Pedrosa J, Castro AG, Kundura L, Loubet P, Sotto A, Muller L, Lefrant JY, Roger C, Claret PG, Duvnjak S, Tran TA, Racine G, zghidi-Abouzid O, Nioche P, Silvestre R, Droit A, Mammano F, Corbeau P, Estaquier J CDD Press
Antibody profiles in COVID-19 convalescent plasma prepared with amotosalen/UVA pathogen reduction treatment (2022) Bagri A, de Assis RR, Tsai CT, Simmons G, Mei ZW, Von Goetz M, Gatmaitan M, Stone M, Di Germanio C, Martinelli R, Darst O, Rioveros J, Robinson PV, Ward D, Ziman A, Settel D, Khan S, Busch MP, Felgner PL, Corash LM Transfusion
Platelet-derived growth factor-BB and white matter hyperintensity
burden in APOE4 carriers (2022) Arunima Kapoor, Daniel A Nation Cerebral Circulation - Cognition and Behavior
Meta-GWAS Reveals Novel Genetic Variants Associated with Urinary Excretion of Uromodulin (2022) Christina B. Joseph, Marta Mariniello, Ayumi Yoshifuji, Guglielmo Schiano, Jennifer Lake, Jonathan Marten, Anne Richmond, Jennifer E. Huffman, Archie Campbell, Sarah E. Harris, Stephan Troyanov, Massimiliano Cocca, Antonietta Robino, Sébastien Thériault, Kai-Uwe Eckardt, Matthias Wuttke, Yurong Cheng, Tanguy Corre, Ivana Kolcic, Corrinda Black, Vanessa Bruat, Maria Pina Concas, Cinzia Sala, Stefanie Aeschbacher, Franz Schaefer, Sven Bergmann, Harry Campbell, Matthias Olden, Ozren Polasek, David J. Porteous, Ian J. Deary, Francois Madore, Philip Awadalla, Giorgia Girotto, Sheila Ulivi, David Conen, Elke Wuehl, Eric Olinger, James F. Wilson, Murielle Bochud, Anna Köttgen, Caroline Hayward and Olivier Devuyst Journal of the American Society of Nephrology
Low T Cell Responsiveness in the Early Phase of COVID-19 Associates with Progression to Severe Pneumonia in Kidney Transplant Recipients (2022) Marion Cremoni, Sébastien Cuozzo, Emanuela Martinuzzi, Susana Barbosa, Nadia Ben Hassen, Filippo Massa, Elisa Demonchy, Matthieu Durand, Olivier Thaunat, Vincent Esnault, Moglie Le Quintrec, Sophie Caillard, Nicolas Glaichenhaus, and Antoine Sicard Viruses
Biomarker Changes in Response to a 12-Week Supplementation of an Oral Nutritional Supplement Enriched with Protein, Vitamin D and HMB in Malnourished Community Dwelling Older Adults with Sarcopenia (2022) Suzette L. Pereira , Marni E. Shoemaker, Susan Gawel, Gerard J. Davis Menghua Luo, Vikkie A. Mustad and Joel T. Cramer Nutrients
Peripheral lymphocyte signaling pathway deficiencies predict treatment response in first-onset drug-naïve schizophrenia (2022) Santiago G. Lago, Jakub Tomasik, Geertje F. Rees, Nitin Rustogi, Javier Vazquez-Bourgon, Sergi Papiol, Paula Suarez-Pinilla, Benedicto Crespo-Facorro, Sabine Bahn Brain Behavior and Immunity
IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines (2022) Siri Tahtinen, Ann-Jay Tong, Patricia Himmels, Jaehak Oh, Andres Paler-Martinez, Leesun Kim, Sara Wichner, Yoko Oei, Mark J. McCarron, Emily C. Freund, Zhainib Adel Amir, Cecile C. de la Cruz, Benjamin Haley, Craig Blanchette, Jill M. Schartner, Weilan Ye, Mahesh Yadav, Ugur Sahin, Lélia Delamarre & Ira Mellman Nature Immunology
Utility of urinary cytokine levels as predictors of the immunogenicity and reactogenicity of AS01-adjuvanted hepatitis B vaccine in healthy adults (2022) Wivine Burny, Caroline Herve, Magalie Caubet, Juan Pablo Yazabal, Arnaud M Didierlaurent Vaccine
Distinct Cellular Immune Responses to SARS-CoV-2 in Pregnant Women (2022) Nardhy Gomez-Lopez, Roberto Romero, Li Tao, Meyer Gershater, Yaozhu Leng, Chengrui Zou, Marcelo Farias-Jofre, Jose Galaz, Derek Miller, Adi L. Tarca, Marcia Arenas-Hernandez, Gaurav Bhatti, Valeria Garcia-Flores, Zhenjie Liu, Robert Para, Tomi Kanninen, Ola Hadaya, Carmen Paredes and Yi Xu Journal of Immunology
Relationship between cerebrospinal fluid neurodegeneration
biomarkers and temporal brain atrophy in cognitively healthy olde r
adults (2022) DidacVidal-Piñeiro, ØysteinSørensen, KajBlennow, Elettra Capogna, Nathalie Bodd Halaas, Ane-VictoriaId, Athanasia Monica Mowinckel, Joana Braga Pereira, Leiv Otto Watne, Henrik Zetterberg, Kristine Beate Walhovd, Anders Martin Fjell Neurobiology of Aging
Pregnancy tailors endotoxin-induced monocyte and neutrophil responses in the maternal circulation (2022) Marcelo Farias-Jofre, Roberto Romero, Jose Galaz, Yi Xu, Li Tao, Catherine Demery-Poulos, Marcia Arenas-Hernandez, Gaurav Bhatti, Zhenjie Liu, Naoki Kawahara, Tomi Kanninen, Zachary Shaffer, Tinnakorn Chaiworapongsa, Kevin R. Theis, Adi L. Tarca & Nardhy Gomez-Lopez Inflammation Research
3Repetitive xenon treatment improves post-stroke sensorimotor and neuropsychiatric dysfunction (2022) Dandekar MP, Yin X, Peng T, Devaraj S, Moarles R, McPherson DD, Huang S Journal of Affective Disorders
Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study (2022) Wesolowska-Andersen A, Brorsson CA, Bizzotto R, Mari A, Tura A, Koivula R, Mahajan A, Vinuela A, Tajes JF, Sharma S, Haid M, Prehn C, Artati A, Hong M, Musholt PB, Kurbasic A, De Masi F, Tsirigos K, Pedersen HK, Gudmundsdottir V, Thomas CE, Banasik K, Jennison C, Jones A, Kennedy G, Bell J, Thomas L, Frost G, Thomsen H, Allin K, Hansen TH, Vestergaard H, Hansen T, Rutters F, Elders P, t'Hart L, Bonnefond A, Canouil M, Brage S, Kokkola T, Heggie A, McEvoy D Cell Reports Medicine
Whole-blood cytokine secretion assay as a high-throughput alternative for assessing the cell-mediated immunity profile after two doses of an adjuvanted SARS-CoV-2 recombinant protein vaccine candidate (2022) De Rosa SC, Cohen KW, Bonaparte M, Fu B, Garg S, Gerard C, Goepfert PA, Huang Y, Larocque D, McElrath MJ, Morris d, Van der Most R, de Bruyn G, Anke Pagnon Clinical & Translational Immunology
Cellular and humoral immunity to SARS-CoV-2 infection in multiple sclerosis patients on ocrelizumab and other disease-modifying therapies: a multi-ethnic observational study (2022) Kister I, Patskovsky Y, Curtin R, Pei J, Perdomo K, Rimler Z, Voloshyna I, Samanovic MI, Cornelius AR, Velmurugu Y, Nyovanie S, Kim J, Tardio E, Bacon TE, Zhovtis L, Ryerson LZ, Raut P, Pedotti R, Hawker K, Raposo C, Priest J, Cabatingan M, Winger RC, Mulligan MJ, Krogsgaard M, Silverman GJ medRxiv
Dissection of depression heterogeneity using proteomic clusters (2022) van Haeringen M, Milaneschi Y, Lamers F, Penninx BWJH, Jansen R Psychological Medicine
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2021
Assessment of advanced glycation end products and receptors and the risk of dementia (2021) Chen J, Mooldijk SS, Licher S, Waqas K, Ikram MK, Uitterlinden AG, Zillikens MC, Ikram MA JAMA Network Open
Sex-specific differences in peripheral blood leukocyte transcriptional response to LPS are enriched for HLA region and X chromosome genes (2021) Stein MM, Conery M, Magnaye KM, Clay SM, Billstrand C, Nicolae R, Naughton K, Ober C, Thompson EE Scientific Reports
A phase 1b trial of the CXCR4 inhibitor mavorixafor and nivolumab in advanced renal cell carcinoma patients with no prior response to nivolumab monotherapy (2021) Choueiri TK, Atkins MB, Rose TL, Alter RS, Yawen J, Niland K, Wang Y, Arbeit R, Parasuraman S, Gan L, McDermott DF Investigational New Drugs
First-in-human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of ALPN-101, a dual CD28/ICOS antagonist, in healthy adult subjects (2021) Yang J, Lickliter JD, Hilson JL, Means GD, Sanderson RJ, Carley K, Tercero A, Manjarrez KL, Wiley JR, Peng SL Clinical and Translational Science
LY3022855, an anti-colony stimulating factor-1 receptor (CSF-1R) monoclonal antibody, in patients with advanced solid tumors refractory to standard therapy: phase 1 dose-escalation trial (2021) Dowlati A, Jarvey RD, Carvajal RD, Hamid O, Klempner SJ, Wook Kauh JS, Peterson DA, Yu D, CHapman SC, Szpurka AM, Carlsen M, Quinlan T, Wesolowski R Investigational New Drugs
Novel approaches to develop biomarkers predicting treatment responses to TNF-blockers (2021) Mezghiche I, Yahia-Cherbal H, Rogge L, Bianchi E Expert Review of Clinical Immunology
Machine learning-based single cell and integrative analysis reveals that baseline mDC predisposition predicts protective Hepatitis B vaccine response (2021) Aevermann B, Shannon CP, Novotny M, Ben-Othman R, Cai B, Zhang Y, Ye JC, Kobor MS, Gladish N, Lee A, Blimke TM, Hancock RE, Llibre A, Duffy D, Koff WC, Sadarangani M, Tebbutt SJ, Kollmann TR, Scheuermann RH medRxiv
Novel signatures associated with systemic lupus erythematosus clinical response to IFN-a/-? inhibition (2021) Seridi L, Cesaroni M, Orillion A, Schreiter J, Chevrier M, Marciniak S, Migone TS, Stohl W, Chatham WW, Furie RA, Benson J, Jordan J Lupus
TNFRSF1B gene variants and related soluble TNFR2 levels impact reilience in Alzheimer's disease (2021) Pillai JA, Bebek G, Khrestian M, Bena J, Bergmann CC, Bush WS, Leverenz JB, Bekris LM Frontiers in Aging Neuroscience
Influence of cell quality on inflammatory biomarkers in COPD sputum supernatant (2021) Pedersen F, Trinkmann F, Abdo M, Kirsten AM, Rabe KF, Watz H, Baraldo S, Saetta M, Hohlfeld JM, Holz O International Journal of Chronic Obstructive Pulmonary Disease
Molecular correlates of response to nivolumab at baseline and on treatment in patients with RCC (2021) Ross-Macdonald P, Walsh AM, Chasalow SD, Ammar R, Papillon-Cavanagh S, Szabo pm, Choueiri TK, Sznol M, Wind-Rotolo M Journal for Immunotherapy for Cancer
Identifying associations among genomic, proteomic and imaging biomarkers via adaptive sparse multi-view canonical correlation analysis (2021) Du L, Zhang J, Liu F, Wang H, Guo L, Han J, the Alzheimer's Disease Neuroimaging Initiative Medical Image Analysis
Primary human dendritic cells and whole-blood based assays to evaluate immuno-modulatory properties of heat-killed commensal bacteria (2021) Norton JE Jr., Kommineni S, Akrivoulis P, Gutierrez DA, Hazuda DJ, Swaminathan G Vaccines
Correlative serum biomarker analyses in the phase 2 trial of lenvatinib-plus-everolimus in patients with metastatic renal cell carcinoma (2021) Lee CH, Motzer RJ, Glen H, Michaelson MD, Larkin J, Minoshima Y, Kanekiyo M, Ikezawa H, Sachdev P, Dutcus CE, Funashashi Y, Voss MH British Journal of Cancer
Muscle damage in systemic sclerosis and CXCL10: The potential therapeutic role of PDE5 inhibition (2021) Corinalesi C, Ross RL, Abignano G, Antinozzi C, Marampon F, di Luigi L, Buch MH, Riccieri V, Lenzi A, Crescioli C, Del Galdo F International Journal of Molecular Sciences
Differential response induced by LPS and MPLA in immunocompetent and septic individuals (2021) Vega CA, Karakike E, Bartolo F, Mouton W, Cerrato E, Brengel-Pesce K, Giamarellos-Bourboulis EJ, Mallet F, Trouillet-Assant S Clinical Immunology
Characterization of the pathophysiological determinants of diarrheagenic Escherichia coli infection using a challenge model in healthy adults (2021) van Hoffen E, Mercenier A, Vidal K, Benyacoub J, Schloesser J, Kardinaal A, Lucas-van de Bos E, van Alen I, Rogero I, Duintjer K, Berendts A, Albers R, Kleerebezem M, Bruggencate ST Scientific Reports
Development of an affordable, sustainable and efficacious plant-based immunomodulatory food ingredient based on bell pepper or carrot RG-I pectic polysaccharides (2021) McKay S, Oranje P, Helin J, Koek JH, Kreijveld E, van den Abbeele P, Phol u, Bothe G, Tzoumaki M, Aparicio-Vergara M Nutrients
Nonclinical development of SRK-181: An anti-latent TGFb1 monoclonal antibody for the treatment of locally advanced or metastatic solid tumors (2021) Welsh BT, Faucette R, Bilic S, Martin CJ, Schurpf T, Chen D, Nicholls S, Lansita J, Kalra A International Journal of Toxicology
Functional immune reconstitution early after allogeneic hematopoietic cell transplantation: A comparison of pre- and post-transplantation cytokine responses in stimulated whole-blood (2021) Gjaerde LK, Brooks PT, Andersen NS, Friss LS, Kornblit B, Petersen SL, Schjodt I, Nielsen SD, Ostrowski SR, Sengelov H Scandinavaian Journal of Immunology
Brentuximab vedotin in combination with nivolumab in relapsed or refractory Hodgkin lymphoma: 3-year study results (2021) Advani R, Moskowitz AJ, Bartlett NL, Vose J, Ramchandren R, Feldman T, LaCasce AS, Christian B, Ansell SM, Moskowitz CH, Brown L, Zhang C, Taft D, Ansari S, Sacchi M, Ho L, Herrera AF Blood
NT-proBNP versus routine clinical risk factors as a predictor of cardiovascular events or death in people with dysglycemia – A brief report from the ORIGIN trial (2021) Wijkman MO, Claggett BL, Pfeffer MA, Pare G, McQueen M, Hess S, Fu Lee S, Gerstein HC Journal of Diabetes and its Complications
Safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine formulations in healthy adults: interim results of a randomised, placebo-controlled, phase 1-2, dose-ranging study (2021) Goepfert PA, Fu B, Chabanon AL, Bonaparte MI, Davis MG, Essink BJ, Frank I, Haney O, Janosczyk H, Keefer MC, koutsoukos M, Kimmel MA, Masotti R, Savarino SJ, Schuerman L, Schwarts H, Sher LD, Smith J, Tavares-Da-Silva F, Gurunathan S, DiazGranados CA, de Bruyn G The Lancet, Infectious Disease
The Effect of a natural oral nutritional supplement on the level of intra-articular inflammatory mediators in patients with osteoarthritis of the knee (2021) Sharkey P, Shah Z, Gross M, Meade T, Davidoff S, Shohat N, Parvizi J Journal of Orthopaedic Experience and Innovation
Regional relationships between CSF VEGF levels and Alzheimer's disease brain biomarkers and cognition (2021) Tubi MA, Kothapalli D, Hapenney M, Feingold FW, Mack WJ, King KS, Thompson PM, Braskie MN Neurobiology of Aging
Pretreatment with ibrutinib reduces cytokine secretion and limits the risk of obinutuzumab-induced infusion-related reactions in patients with CLL: analysis from the iLLUMINATE study (2021) Greil R, Tedeschi A, Moreno C, Anz B, Larratt L, Simkovic M, Gill D, Gribben JG, Flinn IW, Wang Z, Cheung LWK, Nguyen AN, Zhou C, Styles L, Demirkan F Annals of Hematology
Safety, pharmacokinetics, and efficacy of budigalimab with rovalpituzumab teserine in patients with small cell lung cancer (2021) Calvo E, Spira A, de Miguel M, Kondo S, Gazzah A, Millward M, Prenen H, Rottey S, Warburon L, Alanko T, Cassier PA, Yoh K, Italiano A, Moreno V, Peltola K, Seto T, Toyozawa R, Afar DE, Englert S, Komarnitsky P, Lambert S, Parikh A, Vosganian G, Gao B Cancer Treatment and Research Communities
Preclinical and clinical characterization of the ROR?t inhibitor JNJ-61803534 (2021) Xue X, De Leon-Tabaldo A, Luna-Roman R, Castro G, Albers M, Shoetens F, DePrimo S, Devineni D, Wilde T, Goldberg S, Hoffmann T, Fourie AM, Thurmond RL Scientific Reports
Ligand conjugate structure activity relationships and enhanced endosomal escape with a targeted polymer micelle in non-human primates (2021) Holland RJ, Lam K, Ye X, Martin AD, Wood MC, Palmer L, Fraser D, McClintock K, Majeski S, Jarosz A, Lee ACH, Thi EP, Judge A, Heyes J Molecular Therapy
Distinct gene regulatory signatures of dominance rank and social bond strength in wild baboons (2021) Anderson JA, Lea AJ, Voyles TN, Akinyi MY, Nyakundi R, Ochola L, Omondi M, Nyundo F, Zhang Y, Campos FA, Alberts SC, Archie EA, Tung J bioRxiv preprint
The migration of human follicular dendritic cell-like cell is facilitated by matrix metalloproteinase 3 expression that is mediated through TNFa-ERK1/2-AP1 signaling (2021) Pak HK, Kim YW, Nam B, Lee AN, Roh J, Gil M, Liu C, Chung YS, Park CS Journal of Immunology Research
Anti-interleukin-6 antibody clazakizumab in late antibody-mediated kidney transplant rejection: effect on cytochrome P450 drug metabolism (2021) Muhlbacher J, Schorgenhofer C, Doberer K, Durr M, Budde K, Eskandary F, Mayer KA, Schranza S, Ely S, Reiter B, Chong E, Adler SH, Jilma B, Bohmig GA Transplant Internatinoal
Very-low-carbohydrate diet enhances human T-cell immunity through immunometabolic reprogramming (2021) Hirschberger S, Straub G, Effinger D, Marstaller X, Ferstl A, Muller MB, Wu T, Hubner M, Rahmel T, Mascolo H, Exner N, Heb J, Kreth FW, Unger K, Kreth S EMBO Molecular Medicine
First-in-human phase 1 study of budigalimab, an anti-PD-1 inhibitor, in patients with non-small cell lung cancer and head and neck squamous cell carcinoma (2021) Italiano A, Cassier PA, Lin CC, Alanko T, Peltola KJ, Gazzah A, Shiah HS, Calvo E, Cervantes A, Roda D, Tosi D, Gao B, Millward M, Warburton L, Tanner M, Englert S, Lambert S, Parikh A, Afar DE, Vosganian G, Moreno V Cancer Immunology, Immunotherapy
Proteomic correlates of cortical thickness in cognitively normal individuals with normal and abnormal cerebrospinal fluid beta-amyloid 1-42 (2021) Ekblad LL, Visser PJ, Tijims BM, for the Alzheimer's Disease Neuroimaging Initiative Neurobiology of Aging
Improving the power to detect indirect effects in mediation analysis (2021) Kidd J, Lin DY Conrell University
CSF proteomic Alzheimer's disease-predictive subtypes in cognitively intact amyloid negative individuals (2021) Tijms BM, Gobom J, Teunissen C, Dobricic V, Tsolaki M, Verhey F, Popp J, Martinex-Lage P, Vandenberghe R, Lleo A, Luis-Molineuvo J, Engelborghs S, Freund-Levi Y, Foelich L, Bertram L, Lovestone S, Streffer J, Vos S, ADNI, Blennow K, Scheltens P, Zetterberg H, Jelle Visser P Proteomes
Hedgehog interacting protein-expressing lung fibroblasts suppress lymphocytic inflammation in mice (2021) Yun JH, Lee CH, Liu S, Kim EY, Xu S, Curtis JL, Pinello L, Bowler RP, Silverman EK, Hersh CP, Zhou X JCI Insight
NBAS variants are associated with quantitative and qualitative NK and B cell deficiency (2021) Lenz, D, Pahl J, Hauck F, Alameer S, Balasubramanian M, Baric I, Boy N, Church JA, Crushell E, Dick A, Distelmaier F, Gujar J, Indolfi G, Lurz E, Peters B, Schwerd T, Serranti D, Kolker S, Klein C, Hoffmann GF, Prokisch H, Greil J, Cerwenka A, Giese T Staufner C Journal of Clinical Immunology
Phase 1 study in healthy participants of the safety, pharmacokinetics, and pharmacodynamics of enpatoran (M5049), a dual antagonist of toll-like receptors 7 and 8 (2021) Port A, Shaw JV, Klopp-Schulze L, Bytyqi A, Vetter C, Husey E, Mammasse N, Ona V, Bachmann A, Strugala D, Reh C, Goteti K Pharmacology Researh and Perspective
Antitumor necrosis factor-like ligand 1A therapy targets tissue inflammation and fibrosis pathways and reduces gut pathobionts in ulcerative colitis (2021) Hassan-Zahraee M, Ye Z, Baniecki ML, Li X, Hyde CL, Zhang J, Raha N, Karlsson F, Quan J, Ziemek D, Neelakantan S, Lepsy C, Allegretti JR, Romatowski J, Scherl EJ, Klopocka M, Danese S, Chandra DE, Schoenbeck U, Vincent MS, Longman R,Hung KE Inflammatory Bowl Diseases
Discovery and validation of a novel subgroup and therapeutic target in idiopathic multicentric Castleman disease (2021) Pierson SK, Shenoy S, Oromendia AB, Gorzewski AM, Pai RA, Nabel CS, Ruth JR, parente SAT, Arenas DJ, Guilfoyle M, Reddy MP, Weinblatt M, Shadick N, Bower M, Pria AD, Masaki Y, Katz L, Mezey J, Beineke P, Lee D, Tendler C, Kambayashi T, Fossa A, van Rhee F, Fajgenbaum DC Blood Advances
Association of systemic inflammation with depressive symptoms in individuals with COPD (2021) Strollo HC, Nouraie SM, Hoth KF, Riley CM, Karoleski C, Zhang Y, Hanania NA, Bowler RP, Bon J, Sciurba FC International Journal of Chronic Obstructive Pulmonary Disease
A matrix metalloproteinase-generated neoepitope of CRP can identify knee and multi-joint inflammation in osteoarthritis (2021) Alexander Jr LC, McHorse G, Huebner JL, Bay-Jensen AC, Karsdal MA, Kraus VB Arthritis Research & Therapy
Distinct patterns of blood cytokines beyond a cytokine storm predict mortality in COVID-19 (2021) Herr C, Mang S, Mozafari B, Guenther K, Speer T, seibert M, Srikakulam SK, Beisswenger C, Ritzmann F, Keller A, Mueller R, smola S, Eisinger D, Zemlin M, Danziger G, Volk T, Hoersch S, Krawczyk M, Lammert F, Adams T, Wagenpfeil G, Kindermann M, Marcu C, Ataya ZWD, Mittag M, Schwarzkopf K, Custodis F, Grandt D, Schaefer H, Eltges K, Lepper PM, Bals R Journal of Inflammation Research
Associations of the cerebrospinal fluid hepatocyte growth factor with Alzheimer's disease pathology and cognitive function (2021) Zhao LJ, Wang ZT, Ma YH, Zhang W, Dong Q, Yu JT, Tan L, ADNI BMC Neurology
High insulin in early childhood is associated with subsequent asthma risk independent of body mass index (2021) Carr TF, Granell R, Stern DA, Guerra S, Wright A, Halonen M, Henderson J, Martinex FD The Journal of Allergy and Clinical Immunology: In Practice
Validation of the classification for type 2 diabetes into five subgroups: a report from the ORIGIN trial (2021) Pigeyre M, Hess S, Gomez MF, Asplund O, Groop L, Pare G, Gerstein H Diabetologia
Serum peptidome: diagnostic window into pathogenic processes following occupational exposure to carbon nanomaterials (2021) Mostovenko E, Dahm MM, Schubauer-Berigan MK, Eye T, Erdely A, Young TL, Campen MJ, Ottens AK Particle and Fibre Toxicology
Interferon genes are influenced by 17ß-estradiol in SLE (2021) Singh RP, Hahn BH, Bischoff DS Frontiers in Immunology
Soluble amyloid-beta isoforms predict downstream Alzheimer's disease pathology (2021) Povala G, Bellaver B, De Bastiani MA, Brum WS, Ferreira PCL, Bieger A, Pascoal TA, Benedet AL, Souza DO, Araujo RM, Zatt B, Rosa-Neto P, Zmmer ER Research Square
Biomarker signature in cancer patients with and without venous thromboembolism events: a substudy of CASSINI (2021) Khorana A, Barnard J, Wun T, Vijapurkar U, Damaraju CV, Moore K, Wildgoose P, McCrae K Blood Advances
Randomized, double-blind, controlled trial of human anti-LIGHT monoclonal antibody in COVID-19 acute respiratory distress syndrome (2021) Perlin DS, Neil GA, Anderson C, Zafir-Lavie I, Raines S, Ware CF, Wilkins HJ Journal of Clinical Investigation
Combination of atezolizumab and obinutuzumab in patients with relapsed/refractory follicular lymphoma and diffuse large B-cell lymphome: Results from a phase 1b study (2021) Palomba ML, Till BG, Park SI, Morschhauser F, Cartron G, Marks R, Shivhare M, Hong WJ, Raval A, Change AC, Penuel E, Popplewell LL Clinical Lymphoma Myeloma and Leukemia
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2020
Urelumab alone or in combination with rituximab in patients with relapsed or refractory B-cell lymphoma (2020) Timmerman J, Herbaux C, Ribrag V, Zelenetz AD, Houot R, Neelapu SS, Logan T, Lossos IS, Urba W, Salles G, Ramchandren R, Jacobson C, Godwin J, Carpio C, Lathers D, Liu Y, Neely J, Suryawanshi S, Koguchi Y, Levy R American Journal of Hematology
Identifying early pulmonary arterial hypertension biomarkers in systemic sclerosis: Machine learning on proteomics from the DETECT cohort (2020) Bauer Y, de Bernard S, Hickey P, Ballard K, Cruz J, Cornelisse P, Chadha-Boreham H, Distler O, Rosenberg D, Doelberg M, Roux S, Nayler O, Lawrie A European Respiratory Journal
Molecular Epidemiology of Inflammation Link with Type 2 Diabetes and Coronary Heart Disease (2020) Ligthart S Erasmus University Rotterdam
Soluble receptor for advanced glycation end products (sRAGE) as a biomarker for COPD (2020) Pratte KA, Curtis JL, Kechris K, Couper D, Cho MH, Silverman EK, DeMeo DL, Sciurba FC, Zhang Y, Ortega VE, O'Neal W, Gillenwater LA, Lynch DA, Newell Jr JD, Comellas AP, Castaldi PJ, Miller B, Pouwels SD, ten Hacken NHT, Bischoff R, Klont F, Woodruff P, Paine R, Barr RG, Hoidal J, Doerschuk CM, Charbonnier JP, Sung R, Locantore N, Yonchuk J, Tal-Singer R, Jacobson S, Merrill D, Bowler RP Research Square
Cerebrospinal fluid ceruloplasmin levels predict cognitive decline and brain atrophy in people with underlying ß-amyloid pathology (2020) Diouf I, Bush AI, Ayton S Neurobiology of Disease
Characterization of LY2775240, a selective phosphodiesterase-4 inhibitor, in nonclinical models and in healthy subjects (2020) Patel DR, Urva S, Ho S, Buckman CJ, Ma Y, Lim J, Sissons SE, Zuniga MS, Philips D, Cox K, Dairaghi D Clinical and Translational Science
Phase 1b/2a study of galunisertib, a small molecule inhibitor of transforming growth factor-beta receptor I, in combination with standard temozolomide-based radiochemotherapy in patients with newly diagnosed malignant glioma. (2020) Wick A, Desjardins A, Suarez C, Forsyth P, Gueorguieva I, Burkholder T, Cleverly AL, Estrem ST, Wang S, Lahn MM, Guba SC, Capper D, Rodon J Investigational New Drugs
Degree of Genetic Liability for Alzheimer’s Disease Associated with Specific Proteomic Profiles in Cerebrospinal Fluid (2020) Reus LM, Stringer S, Posthuma D, Teunissen CE, Scheltens P, Pijnenburg YAL, Visser PJ, Tijms BM, for the Alzheimer's Disease Neuroimaging Neurology of Aging
Biomarkers and overall survival in patients with advanced hepatocellular carcinoma treated with TGF-ßRI inhibitor galunisertib. (2020) Giannelli G, Santoro A, Kelley RK, Gane E, Paradis V, Cleverly A, Smith C, Estrem ST, Man M, Wang S, Lahn MM, Raymond E, Benhadji KA, Faivre S PLoS One
Measurement of a Surrogate Biomarker for Arginine Vasopressin Secretion in Association with Physiometric and Molecular Biomarkers of Aging. (2020) Guest PC, Bernstein HB, Dobrowolny H, Borucki K, Westphal S, Steiner J Methods in Molecular Biology
Quantitative Assays of Plasma Apolipoproteins. (2020) Poljak A, Duncan MW, Jayasena T, Sachdev PS Methods of Molecular Biology
Characterisation of the pharmacodynamic effects of the P2X7 receptor antagonist JNJ-54175446 using an oral dexamphetamine challenge model in healthy males in a randomised, double-blind, placebo-controlled, multiple ascending dose trial. (2020) Recourt K, van der Aart J, Jacobs G, de Kam M, Drevets W, van Nueten L, Kanhal K, Siebenga P, Zuiker R, Ravenstijn P, Timmers M, van Gerven J, de Boer P Journal of Psychopharmacology
Fenebrutinib versus Placebo or Adalimumab in Rheumatoid Arthritis: A Randomized, Double-Blind, Phase II Trial (ANDES Study). (2020) Cohen S, Tuckwell K, Katsumoto TR, Zhao R, Galanter J, Lee C,, Rae J, Toth B, Ramamoorthi N, Hackney JA, Berman A, Damjanov N, Fedkov D, Jeka S, Chinn W, Townsend MJ, Morimoto AM, Genovese MC Arthritis& Rheumatology
Proteomics as a reliable approach for discovery of blood-based Alzheimer's disease biomarkers: a systematic review and meta-analysis. (2020) Rehiman SH, Lim SM, Neoh CF, Majeed ABA, Chin AV, Tan MP, Kamaruzzaman SB, Ramasamy K Ageing Reserch Reviews
High cytomegalovirus serology and subsequent COPD-related mortality: a longitudinal study (2020) Nenna R, Zhai J, Packard SE, Spangenberg A, Sherrill DL, Martinez FD, Halonen M, Guerra S ERJ Open Research
Systematic investigation of polyurethane biomaterial surface roughness on human immune responses in vitro (2020) Segan S, Jakobi M, Khokhani P, Klimosch S, Billing F, Schneider M, Martin D, Metzger U, Biesemeier A, Xiong X, Mukherjee A, Steuer H BioMed Research International
Elevated serum interlukin-8 is associated with enhanced intratumor neutrophils and reduced clinical benefit of immune-checkpoint inhibitors (2020) Schalper KA, Carleton M, Zhou M, Chen T, Feng Y, Huang SP, Walsh AM, Baxi V, Pandya D, Baradet T, Locke D, Wu Q, Reilly TP, Phillips P, Nagineni V, Gianino N, Gu J, Zhao H, Perez-Gracia JL, Snmamed MF, Melero I Nature Medicine
Synovial tissue transcriptomes of long-standing rheumatoid arthritis are dominated by activated macrophages that reflect microbial stimulation (2020) Smilijanovic B, Grutzkau A, Sorensen T, Grun JR, Vogl T, Bonin M, Schendel P, Stuhlmuller B, Claussnitzer A, Hermann S, Ohrndorf S, Aupperle K, Backhaus M, Radbruch A, Burmester GR, Haupl T Scientific Reports
APOE e4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer’s disease (2020) Konijnenberg E, Tijms BM, Gobom J, Dobricic V, Bos I, Vos S, Tsolaki M, Verhey F, Popp J, Martinez-Lage P, Vandenberghe R, Lleo A, Frolich L, Lovestone S, Streffer J, Bertram L, Blennow K, Teunissen CE, Veerhuis R, Smit AB, Scheltens P, Zetterberg H, Visser PJ Alzheimer's Research & Therapy
A comprehensive systematic review of CSF proteins and peptides that define Alzheimer’s disease (2020) Pedrero-Prieto CM, Garcia-Carpintero S, Frontinan-Rubio J,Llanos-Gonzalez E, Aguilera Garcia C, Alcain FJ, Lindberg I, Duran-Prado M, Peinado J, Rabanal-Ruiz Y Clinical Proteomics
Innate Immune Stimulation of Whole Blood Reveals IFN-1 Hyper-Responsiveness in Type 1 Diabetes (2020) Rodrigues KB, Dufort MJ, Llibre A, Speake C, Jubayer Rahman M, Bondet V, Quiel J, Linsley PS, Greenbaum CJ, Duffy D, Tarbell KV Diabetologia
Serum biomarkers that predict lean mass loss over bed rest in older adults: An exploratory study (2020) Gawel SH, Davis GJ, Luo M, Deutz NEP, Wolfe RR, Pereira SL Clinica Chimica Acta
Multiple Biomarker Approach for the Diagnosis and Therapy of Rheumatoid Arthritis (2020) Savvateeva E, Smoldovskaya O, Feyzkhanova G, Rubina A Critical Reviews in Clinical Laboratory Sciences
Systemic juvenile idiopathic arthritis and recurrent macrophage activation syndrome due to a CASP1 variant causing inflammasome hyperactivation (2020) Jorgensen SE, Christiansen M, Host C, Glerup M, Mahler B, Lausten MM, Gad HH, Hartmann R, Herlin T, Mogensen TH Rheumatology
Comparison of host immune responses to LPS in human using an immune profiling panel, in vivo endotaxemia versus ex vivo stimulation (2020) Tawfik DM, Lankelma JM, Vachot L, Cerrato E, Pachot A, Wiersinga WJ, Textoris J Scientific Reports
Inhibition of cytokine signaling by ruxolitinib and implactions for COVID-19 treatment (2020) Yeleswaram S, Smith P, Burn T, Covington M, Juvekar A, Li Y, Squier P, Langmuir P Clinical Immunology
Serum interleukin-6 and C-reactive protein are associated with survival in melanoma patients receiving immune checkpoint inhibition (2020) Laino AS, Woods D, Vassallo M, Qian X, Tang H, Wind-Rotolo M, Weber J Journal for ImmunoTherapy of Cancer
Proteomic profiling as a diagnotic biomarker for discriminating between bipolar and unipolar depression (2020) Kittel-Schneider S, Hahn T, Haenisch F,McNeill R, Reif A, Bahn S Frontiers in Psychiatry
Elevated plasma cortisol associated with larger ventricles and smaller hippocampal volumes - a study in 2 independent elderly cohorts (2020) Rajagopalan P, Nho K, Risacher SL, Jahanshad N, Boyle CP, Saykin AJ, Thompson PM bioRxiv
The effects of rare SERPINA1 variants on lung function and emphysema in SPIROMICS (2020) Ortega VE, Li X, O'Neal WK, Lackey L, Ampleford E, Hawkins GA, Grayeski P, Laederach A, Barjaktarevic I, Barr RG, Cooper C, Douper D, Han MK, Kanner RE, Kleerup EC, Martinez FJ, Paine R III, Peters SP, Pirozzi C, Rennard SI, Woodruff PG, Hoffman EA, Meyers DA, Bleecker ER American Journal of Respiratory and Critical Care Medicine
Fibroblasts from distinct pancreatic pathologies exhibit disease-specific properties (2020) Barrera LN, Evans A, Lane B, Brumskill S, Oldfield FE, Campbell F, Andrews T, Lu Z, Perez-Mancera PA, Liloglou T, Ashworth M, Jalali M, Dawson R, Nunes Q, Phillips PA, Timms JF, Halloran C, Greenhalf W, Neoptolemos JP, Costello E Cancer Research
Predicting and elucidating the etiology of fatty liver disease: a machine learning modeling and validation study in the IMI DIRECT cohorts (2020) Atabaki-Pasdar N, Ohlsson M, Vinuela A, Frau F, Pomares-Millan H, Haid M, Jones AG, Thomas EL, Koivula RW, Kurbasic A, Mutie PM, Fitipaldi H, Fernandez J, Dawed AY, Giordano GN, Forgie IM, McDonald TJ, Rutters F, Cederberg H, Chaanova E, Dale M, De Masi F, Thomas CE, Allin KH, Hansen TH, Heggie A, Hong MG, Elders PJM, Kennedy G, Kokkola T, Pedersen HK, Mahajan A, McEvoy D, Pattou F, Raverdy V, Haussler RS, Sharma S, Thomsen HS, Vangipurapu J, Vestergaard H, 't Hart LM, Adamski J, Musholt P, Brage S, Brunak S, Dermitzakis E, Frost G, Hansen T, Laakso M, pedersen O, Ridderstrale M, Ruetten H, Hattersley AT, Walker M, Beulens JWJ, Mari A, Schwenk JM, Gupta R, McCarthy MI, Pearson ER, Bell JD, Pavo I, Franks PW PLoS Medicine
A phase I study of ASTX660, an antagonist of inhibitors of apoptosis proteins, in adults with advanced cancers or lymphoma (2020) Mita MM, LoRusso PM, Papadopoulos KP, Gordon MS, Mita AC, Ferraldeschi R, Keer H, Oganesian A, Su XY, Jueliger S, Tolcher AW Clinical Cancer Research
Towards standardization of immune functional assays (2020) Mouton W, Albert-Vega C, Boccard M, Bartolo F, Oriol G, Lopez J, Pachot A, Textoris J, Mallet F, Brengel-Pesce K, Trouillet-Assant S Clinical Immunology
Results of the phase I open label clinical trial SAKK 06/14 assessing safety of intravesical instillation of VPM1002BC, a recombinant mycobacterium bacillus calmette guerin (BCG), in patients with non-muscle invasive bladder cancer and previous failure of conventional BCG therapy (2020) Rentsch CA, Bosshard P, Mayor G, Rieken M, Puschel H, Wirth G, Cathomas R, Parzmair GP, Grode L, Eisele B, Sharma H, Gupta M, Gairola S, Shaligram U, Goldenberger D, Spertini F, Audran R, Enoui M, Beradi S, Hayoz S, Wicki A Oncoimmunology
An integrative study of five biological clocks in somatic and mental health (2020) Jansen R, Verhoeven J, Han LKM, Aberg KA, van den Oord ECGJ, Milaneschi Y, Penninx BWJH bioRxiv
Using the circulating proteome to assess type I interferon activity in systemic lupus erythematosus (2020) Smith MA, Chiang CC, Zerrouki K, Rahman S, White W, Streicher K, Rees WA, Schiffenbauer A, Rider LG, Miller FW, Manna Z, Hasni S, Kaplan M, Siegel R, Sinibaldi D, Sanjuan MA, Casey KA Scientific Reports
Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitnes in old age (2020) Brigger D, Riether C, van Brummelen R, Mosher KI, Shiu A, Ding Z, Zbaren N, Gasser P, Guntern P, Yousef H, Castellano JM, Storni F, Graff-Radford N, Britschgi M, Grandgirard D, Hinterbrandner M, Siegrist M, Moullan N, Hofstetter W, Leib SL, Villiger PM, Auwerx J, Villeda SA, Wyss-Coray T, Noti M, Eggel A Nature Metabolism
Impact of carbohydrate-reduced nutrition in septic patients on ICU: study protocol for a prospective randomised controlled trial (2020) Rahmel T, Hubner M, Koos B, Wolf A, Willemsen KM, Straub G, Effinger D, Adamzik M, Kreth S BMJ Open
Preoperative TruCulture whole blood cytokine response predicts postoperative inflammation in pancreaticoduodenectomy patients - a pilot cohort study (2020) Aasvang EK, Pitter S, Hansen CP, Storkholm JH, Krohn PS, Burgdorf SK, Von Stemann JH, Lundgren JD, Nielsen SD, Kehlet H, Ostrowski SR Scandinavian Journal of Immunology
Basal and LPS-stimulated inflammatory markers and the course of individual symptoms of depression (2020) van Eeden WA, van Hemert AM, Carlier IVE, Penninx BWJH, Fried EI, Schoevers R, Giltay EJ Translational Psychiatry
Immune transriptome of cells infected with enterovirus strains obtained from cases of type 1 diabetes (2020) Poma AM, Genoni A, Broccolo F, Denaro M, Pugliese A, Basolo F, Toniolo A Microorganisms
Inexpensive, non-invasive biomarkers predict Alzheimer transition using machine learning analysis of the Alzheimer's Disease Neuroimaging (ADNI) database (2020) Beltran JF, Wahba BM, Hose N, Shasha D, Kline RP, ADNI PLoS One
Safety and efficacy of neurostimulation with a miniaturised vagus nerve stimulation device in patients with multidrug-refractory rheumatoid arthritis: a two-stage multicentre, randomised pilot study (2020) Genovese MC, Gaylis NB, Sikes D, Kivitz A, Horowitz DL, Peterfy C, Glass EV, Levine YA, Chernoff D The Lancet Rheumatology
Plasma biomarkers of the amyloid pathway are associated with geographic atrophy secondary to age-related macular degeneration (2020) Lashkari K, Teague GC, Beattie U, Betts J,Kumar S, McLaughlin MM, Lopez FJ PLOS One
Model informed dosing regimen and phase I results of the anti-PD-1 antibody budigalimab (ABBV-181) (2020) Powderly J, Spira A, Kondo S, Doi T, Luke JL, Rasco D, Gao B, Tanner M, Cassier PA, Gazzah A, Italiano A, Tosi D, Afar DE, Parikh A, Engelhardt B, Englert S, Lambert SL, Kasichayanula S, Mensing S, Menon R, Vosganian G, Tolcher A Clinical and Translational Science
Reduced chronic toxicity and carcinogenicity in A/J mice in response to life-time exposure to aerosol from a heated tobacco product compared with cigarette smoke (2020) Wong ET, Luettch K, Krishan S, Wong SK, Lim WT, Yeo D, Buttner A, Leroy P, Vuillaume G, Boue S, Hoeng J, Vansheeuwijck P, Peitsch M Toxicological Sciences
Investigating data-driven biological subtypes of sychiatric disorders using specification-curve analysis (2020) Beijers L, van Loo HM, Romeijn JW, Lamers F, Schoevers RA, Wardenaar KJ Psychological Medicine
Rapid tumor vaccine using Toll-like receptor-activated ovarian cancer ascites monocytes (2020) Adams SF, Grimm AJ, Chiang CLL, Mookerjee A, Flies D, Jean S, McCann GA, Michaux J, Pak H, Huber F, Neal C, Dangaj D, Bassani-Sternberg M, Rusakiewicz S, Facciabene A, Coukos G, Gimotty PA, Kandalaft LE Journal for ImmunoTherapy of Cancer
Molecular biomarkers of anti-TNF response in patients with rheumatoid arthritis (2020) Yoosuf N, Maciejewski M, Ziemek D, Jelinsky S, Folkersen, Muller M, Sahlstrom P, Vivar N, Catrina A, Berg L, Klareskog L, Padyukov L, Brynedal B Arthritis Research & Therapy
Preclinical investigations and a first-in-human phase I trial of M4112, the first dual inhibitor of indoleamine 2,3-dioxygenase 1 and tryptophan 2,30dioxygenase 2, in patients with advanced solid tumors (2020) Naing A, Eder JP, Piha-Paul SA, Gimmi C, Hussey E, Zhang S, Hildebrand V, Hosagrahara V, Habermehl C, Moisan J, Papadopoulos KP Journal for ImmunoTherapy of Cancer
Genetics meets proteomics: perspectives for large population-based studies (2020) Suhre K, McCarthy MI, Schwenk JM Nature Reviews Genetics
Modulation of cardiometabolic disease markers by type I interferon inhibition in systemic lupus erythematosus (2020) Casey KA, Smith MA, Sinibaldi D, Seto NL, Playford MP, Wang X, Carlucci PM, Wang L, Illei G, Yu B, Wang S, Remaley AT, Mehta NH, Kaplan MJ, White WI Arthritis Rheumatology
Inflammatory pathway analytes predicting rapid cognitive decline in MCI stage of Alzheimer's disease (2020) Pillai JA, Bena J, Bebek Gurkan, Bekris LM, Bonner-Jackson A, Kou L, Pai A, Sorensen L, Neilsen M, Rao SM, Chance M, Lamb BT, Leverenz JB, Alzheimer's Disease Neuroimaging Initiative Annals of Clinical and Translational Neurology
HepatoScore-14: Measures of biological heterogeneity significantly improve prediction of hepatocellular carcinoma risk (2020) Morris JS, Hassan MM, Zohner YE, Wang Z, Xiao L, Rashid A, Haque A, Abdel-Wahab R, Mohamed YA, Ballard KL, Wolff RA, George B, Li L, Allen G, Weylandt M, Li D, Wang W, Raghav K, Yao J, Amin HM, Kaseb AO Heptology
Exploration of biomarkers to predict clinical improvement of atopic dermatitis in patients treated with dupilumab - a study protocol (2020) Takeshi N, Kenji I, Daisuke O, Satoshi N, Risa TM, Koji M, Susumu I, Hidehisa S, Yudai K, Riichiro A, Mamitaro O, Koji K, Tatsuro O, Tomomitsu M, Yozo I, Akihiko a, Hiroshi K, Keiji T, Hiroshi M, Tatsuyoshi K, Takuya T, Masashi A, Emi N, Akimchi M, Kyoko t, Yukinobu N, Koji S, Chicharu T, YOko K, Rai F, Sakae K, Eishin M, Akio T, Mchihiro H, Natsuko A, Shigetoshi S, Haruna M, Yutaka H, Motoi T, Hiroyuki M, Norito K, Masutaka F Medicine
Neuroinflammation trajectories precede cognitive impairment after experimental meningitis-evidence from an in vivo PET study. (2020) Giridharan VV, Collodel A, Generoso JS, Scaini G, Wassather R, Selvaraj S, Hasbun R, Dal-Pizzol F, Petronilho F, Barichello T Journal of Neuroinflammation
First-in-human, single- and multiple-ascending dose studies in healthy subjects to assess pharmacokinetics, pharmacodynamics, and safety/tolerability of iberdomide, a novel cereblon E3 ligase modulator (2020) Ye Y, Gaudy A, Schafer P, Thomas M, Weiss D, Chen N, Liu L, Xue Y, Carayannopoulos L, Palmisano M Clinical Pharmacology in Drug Development
Comparison of serum and urinary biomarker panels with albumin/creatinine ratio in the prediction of renal function decline in type 1 diabetes. (2020) Colombo M, McGurnaghan SJ, Blackbourn LAK, Dalton RN, Dunger D, Bell S, Petrie JR, Green F, MacRury S, McKnight JA, Chalmers J, Collier A, McKeigue PM, Colhoun HM, Scottish Diabetes Research Network (SDRN) Type 1 Bioresource Investigators Diabetologia
Deciphering heterogeneity of septic shock patients using immune functional assays: a proof of concept study (2020) Albert Vega C, Oriol G, Bartolo F, Lopez J, Pachot A, Rimmele T, Venet F, Leray V, Monneret G, Delwarde B, Brengel-Pesce K, Textoris J, Mallet F, Trouillet-Assant S Scientific Reports
Filgotinib, a JAK1 Inhibitor, Modulates Disease-Related Biomarkers in Rheumatoid Arthritis: Results from Two Randomized, Controlled Phase 2b Trials. (2020) Tarrant JM, Galien R, Li W, Goyal L, Pan Y, Hawtin R, Zhang W, Van der Aa A, Taylor PC Rheumatol Ther
Immune profiling enables stratification of patients with active TB disease or M. tuberculosis infection (2020) Duffy D, Nemes E, Llibre A, Rouilly V, Musvosvi M, Smith N, Filander E, Africa H, Mabwe S, Jaxa L, Charbit B, Mulenga H, the Milieu Interieur Consortium, Tameris M, Walzl G, Malherbe S, Thomas S, Hatherill M, Bilek N, Scriba TJ, Albert ML Clinical Infectious Diseases
Systems biology methods applied to blood and tissue for comprehensive analysis of immune response to hepatitis B vaccine in adults (2020) Ben-Othman R, Cai B, Liu AC, Varankovich N, He D, Blimkie TM, Lee AH, Gill EE, Novotny M, Aevermann B, Drissler s, Shannon CP, McCann S, Marty K, Bjornson G, Edgar RD, Lin DTS, Gladish N, MacIsaac J, Amenyogbe N, Chan Q, Libre A, Collin J, Landais, E, Le K, Reiss SM, Koff WC, Havenar-Daughton C, Heran M, Sangha B, Walt D, Krajden M, Crotty S, Sok D, Briney B, Burton DR, Duffy D, Foster LJ, Mohn WW, Kobor MS, Tebbutt SJ, Brinkman RR, Scheuermann RH, Hancock REW, Kollmann TR, Sadarangani M Frontiers in Immunology
Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis. (2020) Herster F, Bittner Z, Archer NK, Dickhofer S, Eisel D, Eigenbrod T, Knorpp T, Schneiderhan-Marra N, Loffler MW, Kalbacher H, Vierbuchen T, Heine H, Miller LS, Hartl D, Freund L, Schakel K, Heister M, Ghoreschi K, Weber ANR Nature Communications
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals (2020) Fokersen L, Gustafsson S, Qang Q, Hansen DH, Hedman AK, Schork A, Page K, Zhernakova DV, Wu Y, Peteres J, Eriksson N, Bergen SE, Boutin TS, Bretherick AD, Entroth S, Kalnapenkis A, Gadin JR, Suur BE, Chen Y, Matic L, Gale JD, Lee J, Zhang W, Quazi A, Ala-Korpela M, Choi SH, Claringbould A, Danesh J, Smith GD, de Masi F, Elmstahl S, Engstrom G, Fauman E, Fernandez C, Franke L, Franks PW, Giedraitis V, Haley C, Hamsten A, Ingason A, Johansson A, Joshi PK, Lind L, Lindgren CM, Lubitz S, Palmer T, Macdonald-Dunlop E, Magnusson M, Melander O, Michaelsson K, Morris AP, Magi R, Nagle MW, Nilsson PM, Nilsson J, Orho-Melander M, Polasek O, Prins B, Palsson E, Qi T, Sjogren M, Sundstrom J, Surendran P, Vosa U, Werge T, Wernersson R, Westra HJ, Yang J, Zhernakova A, Arnlov J, Fu J, Smith JG, Esko T, Hayward C, Gyllensten U, Landen M, Siegbahn A, Wilson JF, Wallentin L, Butterworth AS, Homes MV, Ingelsson E, Malarstig A Nature Metabolism
Nasal Microbiota Modifies the Effects of Particulate Air Pollution on Plasma Extracellular Vesicles. (2020) Mariana J, Favero C, Carungno M, Pergoli L, Ferrari L, Bonzini M, Cattaneo A, Pesatori AC, Bollati V International Journal of Environmental Research and Public Health
Transcutaneous auricular vagus nerve stimulation reduces pain and fatigue in patients with systemic lupus erythematosus: a randomised, double-blind, sham-controlled pilot trial (2020) Aranow C, Atish-Fregoso Y, Lesser M, Mackay M, Anderson E, Chavan S, Zanos TP, Datta-Chaundhuri T, Bouton C, Tracey KJ, Diamond B Annals of the rheumatic diseases
Dynamic Aspects of Associations in Coronary Artery Disease: From Intracoronary Imaging to Blood Biomarkers (2020) Buljubasic, N. Erasmus University Rotterdam
Methamphetamine increases the proportion of SIV-infected microglia/macrophases, alters metabolic pathways, and elevates cell death pathways: a single-cell analysis (2020) Niu M, Morsey B, Lamberty BG, Emanuel K, Yu F, Leon-Rivera R, Berman JW, Gaskill PJ, Matt SM, Ciborowski PS, Fox HS Viruses
Association of occupational exposures with ex vivo functional immune response in workers handling carbon nanotubes and nanofibers (2020) Schubauer-Berigan MK, Dahm MM, Toennis CA, Sammons DL, Eye T, Kodali V, Zeidler-Erdely PC, Erdely A Nanotoxicology
Efficacy and safety of abatacept in active primary Sjögren's syndrome: results of a phase III, randomised, placebo-controlled trial (2020) Baer AN, Gottenberg JE, St Clair EW, Sumida T, Takeuchi T, Seror R, Foulks G, Nys M, Mukherjee S, Wong R, Ray N, Boothsma H Annals of the Rheumatic Disease
ACE and Type 2 Diabetes Risk: A Mendelian Randomization Study. (2020) Pigeyre M, Sjaarda J, Chong M, Hess S, Bosch J, Yusuf S, Gerstein H, Pare G Diabetes Care
Basal forebrain degeneration and cortisol as biomarkers mediating Alzheimer's disease pathology: a machine learning approach (2020) Nakirikanti AS Research Thesis
Application of the TruCulture® whole blood stimulation system for immune response profiling in cattle (2020) O'Brien MB, McLoughlin RM, Meade KG Veterinary Immunology and Immunopathology
The utility of novel urinary biomarkers in mice for drug development studies (2020) Adedeji AO, Gu YZ, Pourmohamad T, Kanerva J, Chen Y, Atabakhsh E, Tackett MR, Chen F, Bhatt B, Gury T, Dorchies O, Sonee M, Morgan M, Burkey J, Gautier JC, McDuffie JE International Journal of Toxicology
Influence of Genetic Ancestry on Human Serum Proteome (2020) Sjaarda J, Gerstein HC, Kutalik Z, Mohammadi-Shemirani P, Pigeyre M, Hess S, Pare G The American Journal of Human Genetics
Left and right atrial biomarker analysis in atrial fibrillation (2020) Goldberger JJ, Green D, Ringwala S, Andrei AC, Xu Y, Passman R JACC Clinical Electrophysiology
Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia (2020) Narayanan P, Curtis BR, Shen L, Schneider E, Tami JA, Paz S, Burel SA, Tai LJ, Machemer T, Kwoh TJ, Xia S, Shattil SJ, Witztum JL, Engelhardt JA, Henry SP, Monia BP, Hughes SG Nucleic Acid Therapeutics
Immune response profiling of patients with spondyloarthritis reveals signalling networks mediating TNF-blocker function in vivo (2020) Menegatti S, Guillemot V, Latis E, Yahia-Cherbal H, Mittermuller D, Rouilly V, Mascia E, Rosine N, Koturan S, Millot G, Leloup C, Duffy D, Gleizes A, Hacein-Bey-Abina S, Milieu interieur Consortium, Sellam J, Berenbaum F, Miceli C, Dougados M, Bianchi E, Rogge L Ann Rheum Dis
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2019
Early changes in immune, coagulation, and organ function after clinical and experimental polytrauma (2019) Halbgbauer Repositorium der Universität Ulm
TGFb receptor inhibitor galunisertib is linked to inflammation- and remodeling-related proteins in patients with pancreatic cancer (2019) Melisi D, Garcia-Carbonero R, Macarulla T, Pezet D, Deplangue G, Fuchs M, Trojan J, Kozloff M, Simionato F, Cleverly A, Smith C, Wang S, Man M, Driscoll KE, Estrem ST, Lahn MMF, Benhadji KA, Tabernero J Cancer Chemotherapy and Pharmacology
A blood-based signature of cerebrospinal fluid Aß1-42 status (2019) Goudey B, Fung BJ, Schieber C, Faux NG, Alzheimer's Disease Metabolomics Consortium, Alzheimer's Disease Neuroimaging Initiative Scientific Reports
Exploring and redefining Autoimmune polyendocrine syndrome type 1 (2019) Bruserud Skipnes Kommunikasjon, University of Bergen
A randomized, controlled trial on the effects of almonds on lipoprotein response to a higher carbohydrate, lower fat diet in men and women with abdominal adiposity (2019) Williams PT, Bergeron N, Chiu S, Krauss RM Lipids in Health and Disease
External Validation of a Pre-Transplant Biomarker Model (REVERSE) Predictive of Renal Recovery after Liver Transplantation (2019) Levitsky J, Asrani SK, Abecassis M, Ruiz R, Jennings LW, Klintmalm G Hepatology
Biomarkers of Community-Acquired Pneumonia: A Key to Disease Diagnosis and Management (2019) Savvateeva EN, Rubina AY, Gryadunov DA BioMed Research International
Maternal deprivation increases microglial activiation and neuroinflammatory markers in the prefrontal cortex and hippocampus of infant rats (2019) Giridharan VV, Gislaine ZR, Selvaraj S, Scaini G, Barichello T, Quevedo J Journal of Psychiatric Research
Performance of a clinical/proteomic panel to predict obstructive peripheral artery disease in patients with and without diabetes (2019) McCarthy CP, Shrestha S, Ibrahim N, van Kimmenade RRJ, Gaggin HK, Mukai R, Magaret C, Barnes G, Rhyne R, Garasic JM, Januzzi JL Open Heart
VEGF-A from Granuloma Macrophages Regulates Granulomatous Inflammation by a Non-angiogenic Pathway during Mycobacterial Infection (2019) Harding JS, Herbath M, Chen Y, Rayasam A, Ritter A, Csoka B, Hasko G, Michael IP, Faby Z, Nagy A, Sandor M Cell Reports
Synovial fluid biomarkers associated with osteoarthritis severity reflect macrophage and neutrophil related inflammation. (2019) Haraden CA, Huebner JL, Hsueh MF, Li YJ, Kraus VB Arthritis Research & Therapy
Applying modern Omic technologies to the Neuronal Ceroid Lipofuscinoses. (2019) Kline RA, Wishart TM, Mills K, Heywood WE BBA - Molecular Basis of Disease
Increased serum levels of leptin and insulin in both schizophrenia and major depressive disorder: A cross-disorder proteomics analysis (2019) Cakici N, Bot M, Lamers F, Janssen T, van der Haan L, Bahn S, Penninx BWJH, van Beveren NJM European Neuropsychopharmacology
Biomarker panels associated with progression of renal disease in type 1 diabetes. (2019) Colombo M, Valo E, McGurnaghan SJ, Sandholm N, Blackbourn LAK, Dalton RN, Dunger D, Groop PH, McKeigue PM, Forsblom C, Colhoun HM Diabetologia
Novel Drug Targets for Ischemic Stroke Identified Through Mendelian Randomization Analysis of the Blood Proteome. (2019) Chong M, Sjaarda J, Pigeyre M, Mohammadi-Shemirani P, Lali R, Shoamanesh A, Gerstein HC, Pare G Circulation
Identification of Novel Causal Blood Biomarkers Linking Metabolically Favorable Adiposity With Type 2 Diabetes Risk (2019) Pigeyre M, Sjaarda J, Mao S, Chong M, Hess S, Yusuf S, Gerstein H, Pare G Diabetes Care
Immune function as predictor of infectious complications and clinical outcome in patients undergoing solid organ transplantation (the ImmuneMo:SOT study): a prospective non-interventional observational trial. (2019) Drabe CH, Sorensen SS, Rasmussen A, Perch M, Gustafsson F, Rezahosseini O, Lundgren JD, Osrowski SR, Nielson SD BMC Infectious Diseases
Key inflammatory pathway activations in the MCI stage of Alzheimer's disease (2019) Pillai JA, Maxwell S, Bena J, Bekris LM, Rao SM, Chance M, Lamb BT, Leverenz JB Annals of Clinical and Translational Neurology
IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion. (2019) Chan LC, Li CW, Xia W, Hsu JM, Lee HH, Cha JH, Wang HL, Yang WH, Yen EY, Chang WC, Zha Z, Lim SO , Lai YJ, Liu C, Liu J, Dong Q, Yang Y, Sun L, Wei Y, Nie L, Hsu JL, Li H, Ye Q, Hassan MM, Amin HM, Kaseb AO, Lin X, Wang SC, Hung MC The Journal of Clinical Investigation
Plasma cortisol is associated with cerebral hypometabolism across the Alzheimer’s disease spectrum (2019) Wirth M, Lange C, Huijbers W, for the Alzheimer's Disease Neuroimaging Initiative Neurobiology of Aging
Hypothesis: cerebrospinal fluid protein markers suggest a pathway toward symptomatic resilience to AD pathology (2019) Meyer PF, Savard M, Poirier J, Morgan D, Breitner J, for the Alzheimer's Disease Neuroimaging Initiative Alzheimer's & Dementia
T cell phenotypes are associated with serum IgE levels in Amish and Hutterite children (2019) Hrusch CL, Stein MM, Gozdz J, Holbreich M, Von Mutius E, Vercelli D, Ober C, Sperling AI Journal of Allergy and Clinical Immunology
Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6-blockade-refractory idiopathic multicentric Castleman disease. (2019) Fajgenbaum DC, Langan RA, Sada Japp A, Patridge HL, Pierson SK, Singh A, Arenas DJ, Ruth JR, Nabel CS, Stone K, Okumura M, Schwarer A, Jose FF, Hamerschlak N, Wertheim GB, Jordan MB, Cohen AD, Krymskaya V, Rubenstein A, Betts MR, Kambayashi T, van Rhee F, Uldrick TS The Journal of Clinical Investigation
Impaired kidney structure and function in spinal muscular atrophy (2019) Nery FC, Siranosian JJ, Rosales I, Deguise MO, Sharma A, Muhtaseb AW, Nwe P, Johnstone AJ, Zhang R, Fatouraei M, Huemer N, Alves CRR, Kothary R, Swoboda KJ Neurology Genetics
The systemic exercise-released chemokine lymphotactin/XCL1 modulates in vitro adult hippocampal precursor cell proliferation and neuronal differentiation. (2019) Leiter O, Bernas SN, Seidemann S, Overall RW, Horenburg C, Kowal S, Kempermann G, Walker TL Scientific Reports
Morphological and Molecular Changes in Juvenile Normal Human Fibroblasts Exposed to Simulated Microgravity. (2019) Buken C, Sahana J, Corydon TJ, Melnik D, Bauer J, Wehland M, Kruger M, Balk S, Abuagela N, Infanger M, Grimm D Scientific Reports
Targeting the CD40-CD154 Signaling Pathway for Treatment of Autoimmune Arthritis. (2019) Lai JH, Luo SF, Ho LJ Cells
Major depression and enhanced molecular senescence abnormalities in young and middle-aged adults. (2019) Diniz BS, Reynolds Iii CF, Sibille E, Bot M, Penninx BWJH Translational Psychiatry
Type I Interferon Predicts an Alternate Immune System Phenotype in Systemic Lupus Erythematosus (2019) Thanarajasingam U, Muppirala AN, Jensen MA, Ghodke-Puranik Y, Dorschner JM, Vsetecka DM, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold TB ACR Open Rheumatology
Innate Immune Cells and C-Reactive Protein in Acute First-Episode Psychosis and Schizophrenia: Relationship to Psychopathology and Treatment (2019) Steiner J, Frodl T, Schiltz K, Dobrowolny H, Jacobs R, Fernandes BS, Guest PC, Meyer-Lotz G, Borucki K, Bahn S, Bogerts B, Falkai P, Bernstein HG Schizophrenia Bulletin
Plasma total fibroblast growth factor 23 levels are associated with acute kidney injury and mortality in children with acute respiratory distress syndrome. (2019) Hanudel MR, Zinter MS, Chen L, Gala K, Lim M, Guglielmo M, Deshmukh T, Vangala S, Matthay M, Sapru A PLoS One
Amygdalar activity predicts future incident diabetes independently of adiposity (2019) Osborne MT, Ishai A, Hammad B, Tung B, Wang Y, Baruch A, Fayad ZA, Giles JT, Lo J, Shin LM, Grinspoon SK, Koenen KC, Pitman RK, Tawakol A Psychoneuroendocrinology
Therapy with 2'O methly phosphorothioate antisense oligonucleotides causes reversible proteinuria by inhibiting renal protien reabsorption (2019) Janssen MJ, Nieskens TTG, Steevels TAM, Caetano-Pinto P, den Braanker D, Mulder M, Ponstein Y, Jones S, Masereeuw R, den Besten C, Wilmber MJ Molecular Therapy Nucleic Acids
Apremilast Mechanism of Efficacy in Systemic-Naive Patients With Moderate Plaque Psoriasis: Pharmacodynamic Results From the UNVEIL Study (2019) Strober B, Alikhan A, Lockshin B, Shi R, Cirulli J, Schafer P Journal of Dermatological Science
Discovery and validation of a biomarker model (preserve) predictive of renal outcomes after liver transplantation (2019) Levitsky J, Asrani SK, Klintmalm G, Schiano T, Moss A, Chavin K, Miller C, Guo K, Zhao L, Jennings LW, Brown M, Armstrong B, Abecassis M Hepatology
Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab. (2019) Hotchkiss RS, Colston E, Yende S, Crouser ED, Martin GS, Alberson T, Bartz RR, Brakenridge SC, Delano MJ, Park PK, Donnino MW, Tidswell M, Mayr FB, Angus DC, Coopersmith CM, Moldawer LL, Catlett IM, Girgis IG, Ye J, Grasela DM Intensive Care Med
SLE Plasma Profiling Identifies Unique Signatures of Lupus Nephritis and Discoid Lupus (2019) Smith MA, Henault J, Karnell JL, Parker ML, Riggs JM, Sinibaldi D, Taylor DK, Ettinger R, Grant EP, Sanjuan MA, Kolbeck R, Petri MA, Casey KA Scientific Reports
Extracorporeal apheresis therapy for Alzheimer disease-targeting lipids, stress, and inflammation (2019) Bornstein SR, Voit-Bak K, Rosenthal P, Tselmin S, Julius U, Schatz U, Boehm BO, Thuret S, Kempermann G, Reichmann H, Chrousos GP, Licinio J, Wong ML, Schally AV, Straube R Molecular Psychiatry
Functional immune monitoring in severely injured patients - a pilot study. (2019) Halbgebauer R, Kllermann S, Schafer F, Weckbach S, Weiss M, Barth E, Bracht H, Kalbitz M, Gebhard F, Huber-Lang MS, Perl M Scandinavian Journal of Immunology
Large-scale Analyses of Disease Biomarkers and Apremilast Pharmacodynamic Effects (2019) Medvedeva IV, Stokes ME, Eisinger D, LaBrie ST, Ai J, Trotter MWB, Schafer P, Yang R Scientific Reports
A rapid triage test for active pulmonary tuberculosis in adult patients with persistent cough. (2019) Ahmad R, Xie L, Pyle M, Suarez MF, Broger T, Steinberg D, Ame SM, Lucero MG, Szucs MJ, MacMullan M, Berven FS, Dutta A, Sanvictores DM, Tallo VL, Bencher R, Eisinger DP, Dhingra U, Deb S, Ali SM, Mehta S, Fawzi WW, Riley ID, Sazawal S, Premji Z, Black R, Murray CJL, Rodriguez B, Carr SA, Walt DR, Gillette MA Science Translational Medicine
Tumor immune microenvironment and genomic evolution in a patient with metastatic triple negative breast cancer and a complete response to atezolizumab. (2019) Molinero L, Li Y, Chang CW, Maund S, Berg M, Harrison J, Fasso M, O'Hear C, Hedge P, Emens LA Journal for ImmunoTherapy of Cancer
Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors (2019) Piha-Paul SA, Hann CL, French CA, Cousin S, Brana I, Cassier PA, Moreno V, de Bono JS, Duckworth Harward S, Ferron-Brady G, Barbash O, Wyce A, Wu Y, Horner T, Annan M, Parr NJ, Prinjha RK, Carpenter CL, Hilton J, Hong DS, Hass NB, Markowski MC, Dhar A, O'Dwyer PJ, Shapiro GI JNCI Cancer Spectrum
Spebrutinib (CC-292) Affects Markers of B Cell Activation, Chemotaxis, and Osteoclasts in Patients with Rheumatoid Arthritis: Results from a Mechanistic Study. (2019) Schafer PH, Kivitz AJ, Ma J, Korish S, Sutherland D, Li L, Azaryan A, Kosek J, Adams M, Capone L, Hur EM, Hough DR, Ringheim GE Rheumatology and Therapy
Methionine restriction delays aging-related urogenital diseases in male Fischer 344 rats. (2019) Komninou D, Malloy VL, Zimmerman JA, Sinha R, Richie JP Jr GeroScience
A Machine-Learning Approach to Identify a Prognostic Cytokine Signature That Is Associated With Nivolumab Clearance in Patients With Advanced Melanoma. (2019) Wang R, Shao X, Zheng J, Saci A, Qian X, Pak I, Roy A, Bello A, Rizzo JI, Hosein F, Moss RA, Wind-Rotolo M, Feng Y Clinical Pharmacology and Therapeutics
A new synthetic toll-like receptor 1/2 ligand is an efficient adjuvant for peptide vaccination in a human volunteer. (2019) Rammensee HG, Wiesmuller KH, Chandran PA, Zelba H, Rusch E, Gouttefangeas C, Kowalewski DJ, Di Marco M, Haen SP, Walz JS, Gloria YC, Bodder J, Schertel JM, Tunger A, Muller L, Kiebler M, Wehner R, Schmitz M, Jakobi M, Schneiderhan-Marra N, Klein R, Laske K, Artzner K, Backert L, Schuster H, Schwenck J, Weber ANR, Pichler BJ, Kneilling M, la Fougere C, Forchhammer S, Metzler G, Bauer J, Weide B, Schippert W, Stevanovic S, Loffler MW Journal for ImmunoTherapy of Cancer
Novel Biomarkers for Change in Renal Function in People With Dysglycemia. (2019) Gerstein HC, Pare G, McQueen MJ, Lee SF, Bangdiwala SI, Kannt A, Hess A, ORIGIN Trial Investigators Diabetes Care
Blood-based protein mediators of senility with replications across biofluids (2019) Royall DR, Palmer RF, The Alzheimer's Disease Neuroimaging Initiative Brain Communications
Development of a prognostic composite cytokine signature based on the correlation with nivolumab clearance: translational PK/PD analysis in patients with renal cell carcinoma. (2019) Wang R, Zheng J, Shao X, Ishii Y, Roy A, Bello A, Lee R, Zhang J, Wind-Rotolo M, Feny Y Journal for ImmunoTherapy of Cancer
Serum Alpha-1 Antitrypsin Levels and the Clinical Course of Chronic Obstructive Pulmonary Disease (2019) Takei N, Suzuki M, Makita H, Konno S, Shimizu K, Kumura H, Kumura H, Nishimura M International Journal of Chronic Obstructive Pulmonary Disease
Vaccine Protection against Multidrug-Resistant Klebsiella pneumoniae in a Nonhuman Primate Model of Severe Lower Respiratory Tract Infection (2019) Malachowa N, Kobayashi SD, Porter AR, Freedman B, Hanley PW, Lovaglio J, Saturday GA, Gardner DJ, Scott DP, Griffin A, Cordova K, Long D, Rosenke R, Sturdevant DE, Bruno D, Martens C, Kreiswirth BN, DeLeo FR mBio
Autoinflammatory disease with corneal and mucosal dyskeratosis caused by a novel NLRP1 variant (2019) Herlin T, Jorgensen SE, Host C, Mitchell PS, Christensen MH, Lausten M, Larsen DA, Schmidt FI, Christiansen M, Mogensen TH Rheumatology
Adjustment of the multi-biomarker disease activity score to account for age, sex and adiposity in patients with rheumatoid arthritis (2019) Curtis JR, Flake DD 2nd, Weinblatt ME, Shadick NA, Ostergaard M, Hetland ML, Brahe CH, Hwang YG, Furst DE, Strand V, Etzel CJ, Pappas DA, Wang X, Hwang CC, Sasso EH, Gutin A, Hitraya E, Lanchbury JS Rheumatology
Plasma sex hormone-binding globulin predicts neurodegeneration and clinical progression in prodromal Alzheimer's disease (2019) Wu W, Su BJ, Shen XN, Bi YL, Tan CC, Li JQ, Dong Q, Tan L, Alzheimer's Disease Neuroimaging Initiative, Yu JT Cognitive Neuroscience
Metabolomic analyses reveal lipid abnormalities and hepatic dysfunction in non-human primate model for Yersinia pestis (2019) Gautam A, Muhie S, Cakraborty N, Hoke A, Donohue D, Miller SA, Hammamieh R, Jett M Metabolomics
Cortisol associated with hypometabolism across the Alzheimer's disease (2019) Wirth M, Huijbers W, Lange C bioRxiv
Modulation of blood inflammatory markers by benralizumab in patients with eosinophilic airway diseases (2019) Sridhar S, Liu H, Damera G, Newbold P Respiratory Research
SOMAscan-based proteomic measurements of plasma brain natriuretic peptide are decreased in mild cognitive impairment and in Alzheimer's dementia patients (2019) Begic E, Hadzidedic S, Kulaglic A, Ramic-Brkic B, Begic Z, Causevic M PLoS One
VaccHemInf Project: protocol for a prospective cohort study of efficacy, safety and characterisation of immune functional response to vaccinations in haematopoietic stem cell transplant recipients (2019) Conrad A, Boccard M, Valour F, Alcazer V, Tovar Sanchez AT, Chidiac C, Laurent F, Vanhems P, Salles G, Brengel-Pesce K, Meunier B, Trouillet-Assant S, Ader F, Lyyon HEMINF Study Group BMJ Journals
Social history and exposure to pathogen signals modulate social status effects on gene regulation in rhesus macaques (2019) Sanz J, Maurizio PL, Snyder-Mackler N, Simons ND, Voyles T, Kohn J, Michopoulos V, Wilson M, Tung J, Barreiro LB bioRxiv
Inflammatory parameters associated with systemic reactogenicity following vaccinatino with adjuvanted hepatitis B vaccines in humans (2019) Burny W, Marchant A, Herve C, Callegaro A, Caubet M, Fissette L, Gheyle L, Legrand C, Ndour C, Tavares Da Silva F, van der Most R, Willems F, Didierlaurent AM, Yarzabal J, ECR-008 study group Vaccine
Citrulline protects mice from experimental cerebral malaria by ameliorating hypoargininemia, urea cycle changes and vascular leak (2019) Gramaglia I, Velez J, Chang YS, Caparros-Wanderley W, Combes V, Grau G, Stins MF, van der Heyde HC PLoS One
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2018
Evaluation of plasma biomarkers of inflammation in patients with maple syrup urine disease (2018) Scaini G, Tonon T, Moura de Souza CF, Schuck PF, Ferreira GC, Quevedo J, Seda Neto J, Amorim T, Camelo Jr JS, Vitoria Barban Margutti A, Hencke Tresbach R, Sperb-Ludwig F, Boy R, V. de Medeiros PF, Schwards IVD, Luiz Streck E Journal of Inherited Metabolic Disease
Association between IL-6 production in synovial explants from rheumatoid arthritis patients and clinical and imaging response to biologic treatment: A pilot study (2018) Andersen M, Boesen M, Ellegaard K, Soderstrom K, Soe NH, Spee P, Morch UGW, Torp-Pedersen S, Bartels EM, Danneskiold-Samsoe B, Karlsson L, Bliddal H Plos One
Anemia and Adverse Outcomes in a Chronic Obstructive Pulmonary Disease Population with a High Burden of Comorbidities (2018) Putcha N, Fawzy A, Paul GG, Lambert AA, Psoter KJ, Sidhaye VK, Woo J, Wells JM, Labaki WW, Doerschuk CM, Kanner RE, Han MK, Martinez C, Paulin LM, Martinez FJ, Wise RA, O'Neal WK, Barr RG, Hansei NN AnnalsATS
NT-proBNP in stable COPD and future exacerbation risk: Analysis of the SPIROMICS cohort (2018) Labaki WW, Xia M, Murray S, Curtis JL, Barr RG, Bhatt SP, Bleecker ER, Hansel NN, Cooper CB, Dransfield MT, Wells JM, Hoffman EA, Kanner RE, Paine III R, Ortega VE, Peters SP, Krishnan JA, Bowler RP Respiratory Medicine
IL-17 blockade with secukinumab in peripheral spondyloarthritis impacts synovial immunopathology without compromising systemic immune responses (2018) van Mens LJJ, van de Sande MGH, Menegatti S, Chen S, Blijdorp ICP, de Jong HM, Fluri IA, Latuhihin TE, van Kuijk AWR, Rogge L, Yeremenko NG, Baeten DLP Arthritis Rheumatol
Networks of blood proteins in the neuroimmunology of schizophrenia (2018) Jeffries CD, Perkins DO, Fournier M, Do KQ, Cuenod M, Khadimallah I, Domenici E, Addington J, Bearden CE, Cadenhead KS, Cannon TD, Cornblatt BA, Mathalon DH, McGlashan TH, Seidman LJ, Tsuang M, Walker EF, Woods SW Transl Psychiatry
A clinical and proteomics approach to predict the presense of obstructive peripheral arterial disease (From CASABLANCA) (2018) McCarthy CP, Ibrahim NE, van Kimmenade RRJ, Gaggin HK, Simon ML, Gandhi P, Kelly N, Motiwala SR, Mukai R, Magaret CA, Barnes G, Rhyne RF, Garasic JM, Januzzi JL Jr Clin Cardiol
Synergistic Cytokine Effects as Apremilast Response Predictors in Patients With Psoriasis (2018) Garcet S, Nograles K, Correa da Rosa J, Schafer PH, Krueger JG Journal of Allergy and Clinical Immunology
Cellular toxicity of silicon carbide nanomaterials as a function of morphology (2018) Chen F, Li G, Zhao ER, Li J, Hableel G, Lemaster JE, Bai Y, Sen GL, Jokerst JV Biomaterials
Cereblon modulator iberdomide induces degradation of the transcription factor Ikaros and Aiolos: immunomodulation in healthy volunteers and relevance to systemic lupus erythematosus (2018) Schafer PH, Ye Y, Wu L, Kosek J, Ringheim G, Yang Z, Liu L, Thomas M, Palmisano M, Chopra R Ann Rheum Dis
IL-23 secreted by myeloid cells drives castration-resistant prostate cancer (2018) Calcinottoa A, Spataro C, Zagato E, Di Mitri D, Gil V, Crespo M, De Bernardis G, Losa M, Mirenda M, Pasquini E, Rinaldi A, Sumanasuriya S, Lambros MB, Neeb A, Luciano R, Bravi CA, Nava-Rodriques D, Dolling D, Prayer-Galetti T, Ferreira A, Briganti A, Esposito A, Barry S, Yuan W, Sharp A, de Bono J, Alimonti A Nature
Standardized Immunomonitoring: Separating the Signals from the Noise (2018) Duffy D Trends in Biotechnology
Proteomic biomarkers of cognitive impairment in obstructive sleep apnea syndrome (2018) Lal C, Hardiman G, Kumbhare S, Strange C Sleep and Breathing
Effects of an FcyRIIA polymorphism on leukocyte gene expression and cytokine responses to anti-CD3 and anti-CD28 antibodies (2018) Stein MM, Hrusch CL, Sperling AI, Ober C Genes and Immunity
Blood CSF1 and CXCL12 as Causal Mediators of Coronary Artery Disease (2018) Sjaarda J, Gerstein H, Chong M, Yusuf S, Meyre D, Anand SS, Hess S, Pare G Journal of the American College of Cardiology
Identifying the etiology and pathophysiology underlying stunting and environmental enteropathy: study protocol of the AFRIBIOTA project (2018) Vonaesch P, Randremanana R, Gody JC, Collard JM, Giles-Vernick T, Doria M, Vigan-Womas I, Rubbo PA, Etienne A, Andriatahirintsoa EJ, Kapel N, Brown E, Huus KE, Duffy D, Finlay BB, Hasan M, Hunald FA, Robinson A, Manirakiza A, Wegener-Parfrey L, Vray M, Sansonetti PJ BMC Pediatrics
Association between Cytokines and Functional, Hemodynamic Parameters, and Clinical Outcomes in Pulmonary Arterial Hypertension (2018) Joshi AA, Davey RA, Rao Y, Shen K, Benza R, Raina A Pulmonary Circulation
Proteomics in Chronic Arthritis - Will We Finally Have Useful Biomarkers? (2018) Kessel C, McArdle A, Verweyen E, Weinhage T, Wittkowski H, Pennington SR, Foell D Current Rheumatology Reports
Testing a multivariate proteomic panel for TBI biomarker discovery: A track-TBI pilot study (2018) Huie JR, Diaz-Arrastia R, Yue JK, Sorani M, Puccio A, Okonkwo DO, Manley GT, Ferguson AR Journal of Neurotrauma
Early Plasma Matrix Metalloproteinase Profiles: A Novel Pathway in Pediatric Acute Respiratory Distress Syndrom (2018) Zinter MS, Delucchi KL, Kong MY, Orwoll BE, Spicer AS, Lim MJ, Alkhouli MF, Ratiu AE, McKenzie AV, McQuillen PS, Dvorak CC, Calfee CS, Matthay MA, Sapru A American Journal of Respiratory and Critical Care Medicine
Von Willebrand factor and ADAMTS13 activity in relation to risk of dementia: a population-based study (2018) Wolters F, Boender J, de Vries P, Sonneveld M, Koudstaal P, de Maat M, Franco O, Ikram M, Leebeek F, Ikram MA Scientific Reports 2018 Apr
Circulating biomarkers from the phase I trial of sirolimus and autophagy inhibition for patients with lymphangioleiomyomatosis (SAIL). (2018) Lamattina AM, Taveira-Dasilva A, Goldberg HJ, Bagwe S, Cui Y, Rosas IO, Moss J, Henske EP, El-Chemaly S Chest Journal
Altered regulation of the T-cell system in patients with CRPS (2018) Heyn J, Azad SC, Luchting B Inflammation Research
A Multi-site In-depth Evaluation of the Qunaterix Simoa from a User's Perspective (2018) Chunyk A, Joyce A, Fischer S, Dysinger M, Mikulskis A, Jeromin A, Lawrence-Henderson R, Baker D, Yeung D The AAPS Journal 2018
Flares in Rheumatoid Arthritis Patients with Low Disease Activity: Predictability and Association with Worse Clinical Outcomes. (2018) Bechman K, Tweehuysen L, Garrood T, Scott DL, Cope AP, Galloway JB, Ma MHY The Journal of Rheumatology
Determination of the minimally important difference (MID) in multi-biomarker disease activity (MBDA) test scores: impact of diurnal and daily biomarker variation patterns on MBDA scores (2018) Chernoff D, Scott Eastman P, Hwang CC, Flake DD 2nd, Wang X, Kivitz A, Curtis JR Clinical Rheumatology
Comparison of a microsphere-based platform with a multiplex flow cytometric assay for determination of circulating cytokines in the mouse (2018) Stricker-Krongrad A, Shoemake C, Zhong M, Liu J, Bouchard G BMC Clinical Pathology Jan 2018
A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial of BMS-986020, a Lysophosphatidic Acid Receptor Antagonist for the Treatment of Idiopathic Pulmonary Fibrosis (2018) Palmer SM, Snyder L, Todd JL, Soule B, Christian R, Anstrom K, Luo Y, Gagnon R, Rosen G Chest Journal
The association of basal insulin treatment versus standard care with outcomes in anti-GAD positive and -negative subjects. A post-hoc analysis of the ORIGIN-trial (2018) Birkeland KI, Grill V, Wium C, McQueen MJ, Lopez-Jaramillo P, Lee SF, Gerstein HC Diabetes, Obesity and Metabolism
A decade of research on the 17q12-21 asthma locus: Piecing together the puzzle (2018) Stein MM, Thempson EE, Schoettler N, Helling BA, Magnaye KM, Stanhope C, Igartua C, Morin A, Washinton C, Nicolae D, Bonnelykke K, Ober C J Allergy Clin Immunol 2018
Parent of origin gene expression in a founder population identifies two new candidate imprinted genes at known imprinted regions (2018) Mozaffari SV, Stein MM, Magnaye KM, Nicolae DL, Ober C PLoS One
Associations of 26 Circulating Inflammatory and Renal Biomarkers with Near-Infrared Spectroscopy and Long-term Cardiovascular Outcome in Patients Undergoing Coronary Angiography (ATHEROREMO-NIRS Substudy) (2018) Anroedh SS, Akkerhuis KM, Oemrawsingh RM, Garcia-Garcia HM, Brankovic M, Regar E, van Geuns RJ, Serruys PW, Daemen J, Van Mieghem NM, Boersma E, Kardys I Current Atherosclerosis Reports
Blockade of placental growth factor reduces vaso-occlusive complications in murine models of sickle cell disease (2018) Gu JM, Yuam S, Sim D, Abe K, Liu P, Rosenbruch M, Bringmann P, Kauser K Experimental Hematology 2018
Adiponectin in Relation to Coronary Plaque Characteristics on Radiofrequency Intravascular Ultrasound and Cardiovascular Outcome (2018) Marino BCA, Buljubasic N, Akkerhuis M, Cheng JM, Garcia-Garcia HM, Regar E, van Guens RJ, Serruys PW, Boersma E, Kardys I Sociedade Brasileira De Cardiologia
Identifying the molecular and cellular signature of cardiac dilation following myocardial infarction (2018) Lindsey ML, Ma Y, Flynn ER, Winniford MD, Hall ME, DeLeon-Pennell KY BBA - Molecular Basis of Disease
Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury (2018) Proudfood A, Bayliffe A, O'Kane C, Wright T, Serone A, Bareille P, Brown V, Hamid U, Chen Y, Wilson R, Cordy J, Morley P, de Wildt Ruud, Elborn S, Hind M, Chilvres E, Griffiths M, Summers C, McAuley D Thorax
Dose escalation results from a first-in-human, phase I study of glucocorticoid-induced TNF receptor-related protein agonist AMG 228 in patients with advanced solid tumors (2018) Tran B, Carvajal RD, Marabelle A, Patel SP, LoRusso PM, Rasmussen E, Juan G, Upreti VV, Beers C, Ngarmchamnanrith G, Schoffski P Journal for ImmunoTherapy of Cancer
Dendritic cell immunotherapy followed by cART interruption during HIV-1 infection induces plasma protein markers of cellular immunity and neutrophil recruitment (2018) van den Ham HJ, Cooper J, Tomasik J, Bahn S, Aerts J, Oseterhaus A, Gruters R, Andeweg A PLoS One
Clinical pharmacokinetics, pharmacodynamics, safety, and tolerability of JNJ-54175446, a brain permeable P2X7 antagonist, in a randomised single-ascending dose study in healthy participants (2018) Timmers M, Ravenstijn P, Xi L, Triana-Baltzer G, Furey M, Van Hemelryck S, Biewenga J, Ceusters M, Bhattacharya A, van den Boer M, van Nueten L, de Boer P Journal of Psychopharmacology
Peripheral immune system in aging and Alzheimer's disease. (2018) Cao W, Zheng H Molecular Neurodegeneartion
Key Proteins Involed in Spheroid Formation and Angiogenesis in Endothelial Cells After Long-Term Exposure to Simulated Microgravity (2018) Dittrich A, Grimm D, Sahana J, Bauer J, Kruger M, Infanger M, Magnusson N Cellular Physiology and Biochemistry 2018
Serum kidney injury molecule 1 and B2-microglobulin perform as well as larger biomarker panels for prediction of rapid decline in renal function in type 2 diabetes (2018) Colombo M, Looker HC, Farran B, Hess S, Groop L, Palmer CNA, Brosnan MJ, Dalton RN, Wong M, Turner C, Ahlqvist E, Dunger D, Agakov F, Durrington P, Livingstone S, Betteridge J, McKeigue PM, Colhoun HM Diabetologia
Medial Forebrain Bundle Deep Brain Stimulation Reverses Anhedonic-Like Behavior in a Chronic Model of Depression: Importance of BDNF and Inflammatory Cytokines (2018) Dandekar MP, Saxena A, Scaini G, Shin JH, Migut A, Giridharan VV, Zhou Y, Barichello T, Soares JC, Quevedo J, Fenoy AJ Molecular Neurobiology
Allostatic load is associated with psychotic symptoms and decreases withantipsychotic treatment in patients with schizophrenia and ?rst-episodepsychosis (2018) Berger M, Juster RP, Westphal S, Amminger P, Bogerts B, Schiltz K, Bahn S, Steiner J, Sarnyai Z Psychoneuroendocrinology
Phase I study of BNC105P, carboplatin and gemcitabine in partially platinum-sensitive ovarian cancer patients in first or second relapse (ANZGOG-1103) (2018) Lindemann K, Beale PJ, Rossi E, Goh JC, Vaughan MM, Tenney ME, Martyn JK, Sommeijer D, Iglesias JL, Kremmidiotis G, Simpson J, Doolin E, Lavranos TC, Veillard AS, Espinoza D, Stockler MR, Rischin D Cancer Chemotherapy and Pharmacology
Multiple biomarker panel to screen for severe aortic stenosis: results from the CASABLANCA study (2018) Elmariah S, McCarthy C, Ibrahim N, Furman D, Mukai R, Magaret C, Rhyne R, Barnes G, van Kimmenade RRJ, Januzzi Jr JL Open Heart
Phase Ib Study of Glasdegib, A Hedgehog Pathway Inhibitor, in (2018) Savona M, Pollyea D, Stock W, Oehler V, Schroeder MA, Lancet J, McCloskey J, Kantarigian H, Ma WW, Shaik MN, Laird AD, Zeremski M, O'Connell A, Chan G, Cortes JE Clinical Cancer Research
Phase I/II trial of combination of anti-CD3/CD7 immunotoxins for steroid-refractory acute graft-versus-host disease (2018) Groth C, van Groningen LFJ, Matos TR, Bremmers ME, Preijers FWMB, Dolstra H, Reicherts C, Schaap NPM, van Hooren EHG, IntHout J, Masereeuw R, Netea MG, Levine JE, Morales G, Ferrara JL, Blijlevens NMA, van Oosterhout YVJM, Stelljes M, van der Velden WJFM Biology of Blood and Marrow Transplantation
PEGylated IL-10 (Pegilodecakin) Induces Systemic Immune Activation, CD8+ T Cell Invigoration and Polyclonal T Cell Expansion in Cancer Patients (2018) Naing A, Infante JR, Papadopoulos KP, Chan IH, Shen C, Ratti NP, Autio KA, Wong DJ, Patel MR, Ott PA, Falchook GS, Pant S, Hung A, Pekarek KL, Wu V, Adamow M, McCauley S, Mumm JB, Wong P, Van Vlasselaer P, Levegue J, Tannir NM, Oft M Cancer Cell
Embelin and its derivatives unravel the signaling, proin?ammatoryand antiatherogenic properties of GPR84 receptor (2018) Gaidarov I, Anthony T, Gatlin J, Chen X, Mills D, Solomon M, Han S, Semple G, Unett DJ Pharmacological Research
Elevated circulating MMP-9 is linked to increased COPD exacerbation in SPIROMICS and COPDGene (2018) Wells JM, Parker MM, Oster RA, Bowler RP, Dransfield MT, Bhatt SP, Cho MH, Kim V, Curtis JL, Martinez FJ, Paine R 3rd, O'Neal W, Labaki WW, Kaner RJ, Barjaktarevic I, Han MK, Silverman EK, Crapo JD, Barr RG, Woodruff P, Castaldi PJ, Gaggar A JCI Insight
Type I interferon receptor blockade with anifrolumab corrects innate and adaptive immune perturbations of SLE (2018) Casey KA, Guo X, Smith MA, Wang S, Sinibaldi D, Sanjuan MA, Wang L, Illei GG, White WI Lupus Science and Medicine
Biomarkers of diabetic kidney disease (2018) Colhoun HM, Marcovecchio ML Diabetologia
Association of baseline inflammatory markers and the development of negative symptoms in individuals at clinical high risk for psychosis (2018) Goldsmith DR, Haroon E, Miller AH, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Mathalon D, McGlashan T, Seidman L, Tsunag M, Woods SW, Walker EF, Perkins DO Brain, Behavior, and Immunity
Pegbelfermin (BMS-986036), PEGlyated FGF21, in Patients with Obesity and Type 2 Diabetes: Results from a Randomized Phase 2 Study (2018) Charles ED, Neuschwander-Tetri BA, Pablo Frias J, Kundu S, Luo Y, Tirucherai GS, Christrian R Obesity (Silver Spring)
Effects of canagliflozin versus glimepiride on adipokines and in inflammatory biomarkers in type 2 diabetes (2018) Garvey WT, Van Gaal L, Leiter LA, Vijapurkar U, List J, Cuddihy R, Ren J, Davies M Metabolism Clinical and Experimenta
Serum Apolipoprotein E and Other Inflammatory Markers Can Identify Non-Responding Patients to a Dendritic Cell Vaccine (2018) Leeman H, Kaminska E, Green D, Bodman-Smith M, Gravett A, Bodman-Smith K, Copier J, Coulton G, Fusi A, Dalgleish AG Translational Oncology
Serum IP-10 levels and increased DPPIV activity are linked to circulating CXCR3+ T cells in cholestatic HCV patients (2018) Rau M, Schmitt J, Berg T, Kremer AE, Stieger B, Spanaus K, Bengsch B, Romero MR, Marin JJ, Keitel V, Klinker H, Tony HP, Mullhaupt B, Geier A PLoS One
Idiopathic Pulmonary Fibrosis: Prospective, Case-Controlled Study of Natural History and Circulating Biomarkers (2018) Raghu G, Richeldi L, Jagerschmidt A, Martin V, Subramaniam A, Ozoux ML, Esperet CA, Soubrane C Chest
Dominace rank-associated gene expression is widespread, sex-specific, and a precursor to high social status in wild male baboons (2018) Lea AJ, Akinyi MY, Nyakundi R, Mareri P, Kariuki T, Alberts SC, Archie EA, Tung J PNAS
S100A12 and S100A8/9 proteins are biomarkers of articular disease activity in Blau syndrome (2018) Wang L, Rose CD, Foley KP, Anton J, Bader-Meunier B, Brissaud P, Chedeville G, Cimaz R, Fernandez-Martin J, Guly C, Hachulla E, Harjacek M, Mackensen F, Merino R, Modesto C, Hernandez A, Pajot C, Ramanan A, Thatayatikom A, Thomee C, Vastert S, Votta B, Bertin J, Wouters CH Rheumatology
Targeting the CD40-CD40L pathway in autoimmune diseases: Humoral immunity and beyond (2018) Karnell JL, Amcaoglu Rider S, Ettinger R, Kolbeck R Advanced Drug Delivery Reviews
Centrilobular emphysema and coronary artery calcification: mediation analysis in the SPIROMICS cohort (2018) Bhatt SP, Nath HP, Kim YI, Ramachandran R, Watts JR, Terry NLJ, Sonavane S, Deshmane SP, Woodruff PG, Oelsner EC, Bodduluri S, Han MK, Labaki WW, Michael Wells J, Martinez FJ, Barr RG, Dransfield MT, SPIROMICS investigators Respiratory Research
Testosterone, sex hormone-binding globulin and risk of cardiovascular events: A report from the Outcome Reduction with an Initial Glargine Intervention trial (2018) Wang A, Arver S, Boman K, Gerstein HC, Fu Lee S, Hess S, Ryden L, Mellbin LG Preventive Cardiology
RNA-antimicrobial peptide complexes fuel a TLR- and NETosis-mediated inflammatory cycle of neutrophil activation in psoriasis (2018) Herster F, Bittner Z, Dickhoefer S, Eisel D, Eigenbrod T, Knorpp T, Schneiderhan-Marra N, Loeffler MW, Hartl D, Freund L, Schaekel K, Heiser M, Ghoreschi K, Weber ANR bioRxiv
Toxoplasma gondii inactivates human plasmacytoid dendritic cells by functional mimicry of IL-10 (2018) Piotr L, Zhao Y, Singh S, Dai J, Yap GS, Fitzgerald-Bocarsly P The Journal of Immunology
Drug-induced Obstructive and Retrograde Nephropathy Associated with a2u-globulin in Male Rats (2018) Jacobsen B, Freichel C, Eichinger-Chapelon A, Brink A, Hoflack JC, Albassam M, Lenz B Toxocologic Pathology
Pharmacokinetics of Telavancin at Fixed Doses in Normal-Body-Weight and Obese (Classes I, II and III) Adult Subjexts (2018) Bunnell KL, Pai MP, Sikka M, Bleasdale S, Wenzler E, Danziger LH, Rodvold KA Antimicrobial Agents and Chemotherapy
PF-04447943, a Phosphodiesterase 9A Inhibitor, in Stable Sickle Cell Disease Patients: A Phase Ib Randomized, Placebo-Controlled Study (2018) Charnigo RJ, Beidler D, Rybin D, Pittman DD, Tan B, Howard J, Michelson AD, Frelinger AL II, Clark N Clinical and Translational Science
Lower serum IgA is associated with COPD exacerbation risk in SPIROMICS (2018) Putcha N, Paul GG, Azar A, Wise RA, O'Neal WK, Dransfield MT, Woodruff PG, Curtis JL, Comellas AP, Drummond MB, Lambert AA, Paulin LM, Fawzy A, Kanner RE, Paine R 3rd, Han MK, Martinez FJ, Bowler RP, Barr RG, Hansel NN, SPIROMICS investigators PLoS One
Carbon nanotube and nanofiber exposure and sputum and blood biomarkers of early effect among U.S. workers (2018) Beard JD, Erdely A, Dahm MM, de Perio MA, Birch ME, Evans DE, Fernback JE, Eye T, Kodali V, Mercer RR, Bertke SJ, Schubauer-Berigan MK Environmental Internation 116 (2018)
Digital Health: a new dimension in rheumatology patient care (2018) Kataria S, Ravindran V Rheumatology International
CSF1R+ macrophages sustain pancreatic tumor growth through T cell suppression and maintenance of key gene programs that define the squamous subtype (2018) Candido J, Morton JP, Bailey P, Barry ST, Balkwill FR, Sansom OJ Cell Reports
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2017
Three-dimensional growth of human endothelial cells in an automated cell culture experiment container during the SpaceX CR-8 ISS space mission - The SPHEROIDS project. (2017) Pietsch J, Gass S2, Nebuloni S, Echegoyen D, Riwaldt S, Baake C, Bauer J, Corydon TJ, Egli M, Infanger M, Grimm D Biomaterials
Prophylactic Treatment with Cerium Oxide Nanoparticles Attenuate Hepatic Ischemia Reperfusion Injury in Sprague Dawley Rats. (2017) Manne NDPK, Arvapalli R, Graffeo VA, Bandarupalli VVK, Shokuhfar T, Patel S, Rice KM, Ginjupalli GK, Blough ER Cell Physiol Biochem
Toxicity of the main electronic cigarette components, propylene glycol, glycerin, and nicotine, in Sprague-Dawley rats in a 90-day OECD inhalation study complemented by molecular endpoints. (2017) Phillips B, Titz B, Kogel U, Sharma D, Leroy P, Xiang Y, Vuillaume G, Lebrun S, Sciuscio D2, Ho J, Nury C2, Guedj E, Elamin A, Esposito M, Krishnan S, Schlage WK, Veljkovic E, Ivanov NV, Martin F, Peitsch MC, Hoeng J, Vanscheeuwijck P Food Chem Toxicol.
The role of anxious distress in immune dysregulation in patients with major depressive disorder. (2017) Gaspersz R, Lamers F, Wittenberg G, Beekman ATF, van Hemert AM, Schoevers RA, Penninx BWJH Transl Psychiatry
CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN. (2017) Fardo DW, Katsumata Y, Kauwe JS, Deming Y, Harari O, Cruchaga C; Alzheimer's Disease Neuroimaging Initiative, Nelson PT Exp Gerontol
Clinical Features of Psoriatic Arthritis: a Comprehensive Review of Unmet Clinical Needs. (2017) McArdle A, Pennington S, FitzGerald O Clin Rev Allergy Immunol.
Inflammatory profile analysis reveals differences in cytokine expression between smokers, moist snuff users, and dual users compared to non-tobacco consumers. (2017) Sgambato JA, Jones BA, Caraway JW, Prasad GL Cytokine
The impact of micronutrient status on health: correlation network analysis to understand the role of micronutrients in metabolic-inflammatory processes regulating homeostasis and phenotypic flexibility. (2017) van den Broek TJ, Kremer BH, Marcondes Rezende M, Hoevenaars FP, Weber P, Hoeller U, van Ommen B, Wopereis S Genes Nutr
Peripheral biomarkers of major depression and antidepressant treatment response: Current knowledge and future outlooks (2017) Gadad BS, Jha MK, Czysz A, Furman JL, Mayes TL, Emslie MP, Trivedi MH J Affect Disord
Soluble intercellular adhesion molecule-1: a potential biomarker for pain intensity in chronic pain patients. (2017) Luchting B, Hinske LC, Rachinger-Adam B, Celi LA, Kreth S, Azad SC Biomark Med
Serum proteins mediate depression’s association with dementia (2017) Royall DR, Al-Rubaye S, Bishnoi R, Palmer RF Plos One
In Vivo Toxicity Assessment of Occupational Components of the Carbon Nanotube Life Cycle To Provide Context to Potential Health Effects. (2017) Bishop L, Cena L, Orandle M, Yanamala N, Dahm MM, Birch ME, Evans DE, Kodali VK, Eye T1, Battelli L, Zeidler-Erdely PC, Casuccio G, Bunker K, Lupoi JS, Lersch TL, Stefaniak AB, Sager T, Afshari A, Schwegler-Berry D, Friend S, Kang J, Siegrist KJ, Mitchell CA, Lowry DT, Kashon ML, Mercer RR, Geraci CL, Schubauer-Berigan MK, Sargent LM, Erdely A. ACS Nano.
Effects of Traumeel (Tr14) on recovery and inflammatory immune response after repeated bouts of exercise: a double-blind RCT. (2017) Muders K, Pilat C, Deuster V, Frech T, Krüger K, Pons-Kuhnemann J, Mooren FC Eur J Appl Physiol.
Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy (2017) Gnjatic S, Bronte V, Brunet LR, Butler MO, Disis ML, Galon J, Hakansson LG, Hanks BA, Karanikas V, Khleif SN, Kirkwood JM, Miller LD, Schendel DJ, Tanneau I, Wigginton JM and Butterfield LH J Immunother Cancer
Effect of DHA supplementation on oxylipin levels in plasma and immune cell stimulated blood. (2017) Schuchardt JP, Ostermann AI, Stork L, Fritzsch S, Kohrs H, Greupner T, Hahn A, Schebb NH Prostaglandins Leukot Essent Fatty Acids
Homeobox, Wnt, and Fibroblast Growth Factor Signaling is Augmented During Alveogenesis in Mice Lacking Superoxide Dismutase 3, Extracellular (2017) Thimraj TA, Birru RL, Mitra A, Schulz H, Leikauf GD, Ganguly K Lung
The REAnimation Low Immune Status Markers (REALISM) project: a protocol for broad characterisation and follow-up of injury-induced immunosuppression in intensive care unit (ICU) critically ill patients (2017) Rol ML, Venet F, Rimmele T, Moucadel V, Cortez P, Quemeneur L, Gardiner D, Griffiths A, Pachot A, Textoris J, Monneret G, On behalf of the REALISM study group BMJ Open
A multivariate predictive modeling approach reveals a novel CSF peptide signature for both Alzheimer ’s Disease state classification and for predicting future disease progression (2017) Llano DA, Bundela S, Mudar RA, Devanarayan V Plos One
PH20 is not expressed in murine CNS and oligodendrocyte precursor cells (2017) Marella M, Ouyang J, Zombeck J, Zhao C, Huang L, Connor RJ, Phan KB, Jorge MC, Printz MA, Paladini RD, Gelb AB, Huang Z, Frost GI, Sugarman BJ, Steinman L, Wei G, Shepard HM, Maneval DC, Lapinskas PJ Ann Clin Transl Neurol
Novel inflammatory markers for incident pre-diabetes and type 2 diabetes: the Rotterdam Study (2017) Brahimaj A, Ligthart S, Ghanbari M, Ikram MA, Hofman A, Franco OH, Kavousi M, Dehghan A Eur. J. Epidemiol.
The AT04A vaccine against proprotein convertase subtilisin/kexin type 9 reduces total cholesterol, vascular inflammation, and atherosclerosis in APOE*3Leiden. CETP mice (2017) Landlinger C, Pouwer MG, Juno C, van der Hoorn J, Pieterman EJ, Jukema JW, Staffler G, Princen H, and Galabova, G Eur. Heart J.
Standardized whole blood stimulation improves immunomonitoring of induced immune responses in multi-center study (2017) Duffy D, Rouilly V, Braudeau C, Corbière V, Djebali R, Ungeheuer MN, Josien R, LaBrie ST, Lantz O, Louis D, Martinez-Caceres E, Mascart F, Ruiz de Morales JG, Ottone C, Redjah L, Guen N, Savenay A, Schmolz M, Toubert A, Albert ML Clin Immunol
Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment. (2017) Steggerda SM, Bennett MK, Chen J, Emberley E, Huang T, Janes JR, Li W, MacKinnon AL, Makkouk A, Marguier G, Murray PJ, Neou S, Pan A, Parlati F, Rodriguez MLM, Van de Velde LA, Wang T, Works M, Zhang J, Zhang W, Gross MI J Immunother Cancer
Few serum proteins mediate APOE’s association with dementia. (2017) Royall DR, Al-Rubaye S, Bishnoi R, Raymond PF PLOS ONE
Human umbilical cord plasma proteins revitalize hippocampal function in aged mice. (2017) Castellano JM, Mosher KI, Abbey RJ, McBride AA, James ML, Berdnik D, Shen JC, Zou B, Xie XS, Tingle M, Hinkson IV, Angst MS, Wyss-Coray T Nature
The impact of antiretroviral therapy on iron homeostasis and inflammation markers in HIV-infected patients with mild anemia. (2017) Quiros-Roldan E, Castelli F, Lanza P, Pezzoli C, Vezzoli M; Inflammation in HIV Study Group, Biasiotto G, Zanella I J Transl Med.
Dietary Buglossoides Arvensis Oil Increases Circulating n-3 Ployunsaturated Fatty Acids in a Dose Dependent Manner and Enhances Lipopolysaccharide-Stimulated Whole Blood Interleukin-10-A Randomized Placebo-Controlled Trial. (2017) Lefort N, LeBlanc R, Surette M Nutrients
Serum thyroid-stimulating hormone and interleukin-8 levels in boys with autism spectrum disorder (2017) Singh S, Yazdani U, Gadad B, Zaman S, Hynan LS, Roatch N, Schutte C, Marti CN, Hewitson L and German DC J. Neuroinflammation
Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges. (2017) Piasecka B, Duffy D, Urrutia A, Quach H, Patin E, Posseme C, Bergstedt J, Charbit B, Rouilly V, MacPherson CR, Hasan M, Albaud B, Gentien D, Fellay J, Albert ML, Quintana-Murci L, Milieu Intérieur Consortium Proc Natl Acad Sci U S A
Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study. (2017) Steele NZ, Carr JS, Bonham LS, Geier EG, Damotte V, Miller ZA, Desikan RS, Boehme KL, Mukherjee S, Crane PK, Kauwe JS, Kramer JH, Miller BL, Coppola G, Hollenbach JA, Huang Y, Yokoyama JS PloS Med.
Cigarette smoke disrupts monolayer integrity by altering epithelial cell-cell adhesion and cortical tension. (2017) Nishida K, Brune KA, Putcha N, Mandke P, O'Neal WK, Shade D, Srivastava V, Wang M, Lam H, An SS, Drummond MB, Hansel NN, Robinson DN, Sidhaye VK. Am J Physiol Lung Cell Mol Physiol
Relation of antioxidant capacity of diet and markers of oxidative status with C-reactive protein and adipocytokines: a prospective study. (2017) Stringa N, Brahimaj A, Zaciragic A, Dehghan A, Ikram MA, Hofman A, Muka T, Kiefte-de Jong JC, Franco OH Metab.
Do single or sequential measurements of leptin and adiponectin in plasma have prognostic value in pulmonary arterial hypertension? (2017) Tonelli AR, Fares WH, Dakkak W, Rao Y, Zhou X, Dweik RA Pulm Circ
Impact of Maternal antibodies and infant gut microbiota on the immunogenicity of rotacirus vaccines in African, Indian, and European infants: protocol for a prospective cohort study. (2017) Sindhu KN, Cunliffe N, Peak M, Turner M, Darby A, Grassly N, Gordon M, Dube Q, Babji S, Praharaj I, Verghese V, Iturriza-Gomara M, Kang G BMJ
Altered Expression of MicroRNAs in Rheumatoid Arthritis (2017) Tavasolian E, Abdollahi E, Rezaei R, Momtazi AA, Henrotin Y, Sahebkar A J. Cell. Biochem.
Immunodepression after CPB: Cytokine dynamics and clinics after pediatric cardiac surgery – A prospective trial (2017) Justus G, Walker C, Rosenthal LM, Berger F, Miera O, Schmitt KR Cytokine
Vitamin D-deficiency and sex-specific dysregulation of placental inflammation (2017) Liu NQ, Larner DP, Yao Q, Chun RF, Ouyang Y, Zhou R, Tamblyn JA, Wagner CL, Hewison M J Steroid Biochem Mol Biol.
Usefulness of Multiple Biomarkers for Predicting Incident Major Adverse Cardiac Events in Patients Undergoing Diagnostic Coronary Angiography (From the Catheter Sampled Blood Archive in Cardiovascular Diseases [CASABLANCA] Study) (2017) McCarthy CP, Van Kimmenade R, Gaggin HK, Simon ML, Ibrahim NE, Gandhi P, Kelly N, Motiwala SR, Belcher AM, Harisiades J, Magaret CA, Rhyne RF, Januzzi Jr. JL Am J Cardiol
Exploring hepsin functional genetic variation association with disease specific protein expression in bipolar disorder: Applications of a proteomic informed genomic approach (2017) Nassan M, Jia Y, Jenkins G, Colby C, Feeder S, Choi D, Veldic M, McElroy SL, Bond DJ, Weinshilboum R, Biernacka JM, Frye MA J Psychiatr Res
A Multi-Biomarker Disease Activity Score and the Choice of Second-Line Therapy in Early Rheumatoid Arthritis after Methotrexate Failure (2017) Hambardzumyan K, Saevarsdottir S, Forslind K, Petersson IF, Wallman JK, Ernestam S, Bolce RJ, van Vollenhoven RF Arthritis Rheumatol
Neuronal Pentraxin 2 predicts medial temporal atrophy and memory decline across the Alzheimer's disease spectrum. (2017) Swanson A, Willette AA; Alzheimer’s Disease Neuroimaging Initiative. Brain Behav Immun.
Complexity of Macrophage Migration Inhibitory Factor (MIF) and Other Angiogenic Biomarkers Profiling in Pulmonary Arterial Hypertension. (2017) Marshall JD, Sauler M, Tonelli A, Rao Y, Bucala R, Lee P, Fares W Pulm Circ.
Changes in IL-17A, macrophage-derived chemokine and adiponectin following treatment of psoriasis with calcipotriol plus betamethasone dipropionate aerosol foam: results from the PSO-ABLE study. (2017) Røpke M, Bulai Livideanu C, Kaldate R, Snel A, Paul C Br J Dermatol.
Altered Immune Activation and IL-23 Signaling in Response to Candida albicans in Autoimmune Polyendocrine Syndrome Type 1 (2017) Bruserud O, Bratland E, Hellesen A, Delaleu N, Reikvam H, Oftedal BE, and Wolff A Front Immunol.
A randomised, placebo-controlled trial of anti-interleukin-1 receptor 1 monoclonal antibody MEDI8968 in chronic obstructive pulmonary disease. (2017) Calverley PMA, Sethi S, Dawson M, Ward CK, Finch DK, Penney M, Newbold P, van der Merwe R Respir Res.
Inflammatory proteins in nasal lavage of workers exposed to occupational agents. (2017) Castano R, Yucesoy B, Johnson VJ, Castellanos L, Cartier A Clin Exp Allergy
Nintedanib macrophage activation and ameliorates vascular and fibrotic manifestations in the Fra2 mouse model of systemic sclerosis (2017) Huang J, Maier C, Zhang Y, Soare A, Dees C, Beyer C, Harre U, Chen CW, Distler O, Schett G, Wollin L, Distler JHW Ann Rheum Dis.
Intrathecal 2-hydroxypropyl-ß-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1-2 trial. (2017) Ory DS, Ottinger EA, Farhat NY, King KA, Jiang X, Weissfeld L, Berry-Kravis E, Davidson CD, Bianconi S, Keener LA, Rao R, Soldatos A, Sidhu R, Walters KA, Xu X, Thurm A, Solomon B, Pavan WJ, Machielse BN, Kao M, Silber SA, McKew JC, Brewer CC, Vite CH, Walkley SU, Austin CP, Porter FD Lancet
The Orally Available Selective Axl Inhibitor BGB324 Induces Diversification of the Immune Repertoire and Specific Changes in Plasma Biomarker Profiles (2017) Loges S, Gjertsen BT, Heuser M, Chromik J, Ben-Batalla I, Akyuz N, Micklem D, Brown A, Lorens J, Yule M, Kebenko M, Janning M, Binder M, Fiedler W, Cortes J Blood
Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons. (2017) Parviainen L, Dihanich S, Anderson GW, Wong AM, Brooks HR, Abeti R, Rezaie P, Lalli G, Pope S, Heales SJ, Mitchison HM, Williams BP, Cooper JD Acta Neuropathol Commun.
A Multibiomarker Disease Activity Score for Rheumatoid Arthritis Predicts Radiographic Joint Damage in the BeSt Study (2017) Markusse IM, Dirven L, van den Broek M, Bijkerk C, Han K.H, Ronday H.K, Bolce R, Sasso E, Kerstens P, Lems WF, Huizinga T, and Allaart CF J Rheumatol.
Assessing biological and technological variability in protein levels measured in pre-diagnostic plasma samples of women with breast cancer. (2017) Yeh CY, Adusumilli R, Kullolli M, Mallick P, John EM, Pitteri SJ Biomark Res.
An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study (2017) Maher TM, Oballa E, Simpson JK, Porte J, Habgood A, Fahy WA, Flynn A, Monlyneaux PL, Braybrooke R, Divyateja H, Parfrey H, Rassl D, Russell AM, Saini G, Renzoni EA, Duggan AM, Hubbard R, Wells AU, Lukey PT, Marshall RP, Jenkins RG Lancet Respir Med
Cytokine Release and Focal Adhesion Proteins in Normal Thyroid Cells Cultured on the Random Positioning Machine. (2017) Warnke E, Pietsch J, Kopp S, Bauer J, Sahana J, Wehland M, Krüger M, Hemmersbach R, Infanger M, Lützenberg R, Grimm D Cell Physiol Biochem.
Perspectives on using a multiplex human kidney safety biomarker panel to detect cisplatin-induced tubular toxicity in male and female Cynomolgus monkeys. (2017) Chen Y, Dale Thurman J, Kinter LB, Bialecki R, Eric McDuffie J Toxicol Appl Pharmacol.
Biomarker-guided stratification of autoimmune patients for biologic therapy. (2017) Ivison S, Des Rosiers C, Lesage S, Rioux JD, Levings MK. Curr Opin Immunol.
Exercise training reverses inflammation and muscle wasting after tobacco smoke exposure. (2017) Krüger K, Seimetz M, Ringseis R, Wilhelm J, Pichl A, Couturier A, Eder K, Weissmann N, Mooren FC Am J Physiol Regul Integr Comp Physiol.
IL-18 associated with lung lymphoid aggregates drives IFN? production in severe COPD. (2017) Briend E, Ferguson GJ, Mori M, Damera G, Stephenson K, Karp NA, Sethi S, Ward CK, Sleeman MA, Erjefält JS, Finch DK Respir Res.
Randomized clinical study of safety, pharmacokinetics, andpharmacodynamics of RIPK1 inhibitor GSK2982772 in healthyvolunteers (2017) Weisel K, Scott NE, Tompson DJ, Votta BJ, Madhavan S, Povey K, Wolstenholme A, Simeoni M, Rudo T, Richards-Peterson L, Sahota T, Wang JE, Lich J, Finger J, Verticelli A, Reilly M, Gough PJ, Harris PA, Bertin J, Wang M Pharmacol Res Perspect.
Inflammatory profile discriminates clinical subtypes in LRRK2-associated Parkinson's disease (2017) Brockmann K, Schulte C, Schneiderhan-Marra N, Apel A, Pont-Sunyer C, Vilas D, Ruiz-Martinez J, Langkamp M, Corvol JC, Cormier F, Knorpp T, Joos TO, Bernard A, Gasser T, Marras C, Schule B, Aasly JO, Foroud T, Marti-Masso JF, Brice A, Tolosa E, Berg D, Maetzler W. Eur J Neurol
Protein Biomarker Druggability Profiling (2017) Mani S, Cannon D, Ohls R, Oprea T, Mathias S, Ballard K, Ursu O, Bologa C J Biomed Inform
Proteomics to predict the response to tumour necrosis factor-a inhibitors in rheumatoid arthritis using a supervised cluster-analysis based protein score (2017) Cuppen BVJ, Fritsch-Stork RDE, Eekhout, W de Jager I, Marijnissen AC, Bijlsma JWJ, Custers M, Van Laar JM, Lafeber FPJG, Welsing PMJ & on behalf of all Society for Rheumatology Research Utrecht (SRU) investigators Scand J Rheumatol
Assessment of Proteomic Measures Across Serious Psychiatric Illness. (2017) Schulz SC, Overgaard S, Bond DJ, Kaldate R. Clin Schizophr Relat Psychoses
Biosynthesis of cerium oxide nanoparticles and their effect on lipopolysaccharide (LPS) induced sepsis mortality and associated hepatic dysfunction in male Sprague Dawley rats. (2017) Chen G, Xu Y Mater Sci Eng C Mater Biol Appl.
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2016
Assessment of Urine Proteomics in Type 1 Primary Hyperoxaluria*American Journal of Nephrology (2016) Brooks ER, Hoppe B, Milliner DS, Salido E, Rim J, Krevitt LM, Olson JB, Price HE, Vural G, Langman CB American Journal of Nephrology
Safety, Antitumor Activity, and Immune Activation of Pegylated Recombinant Human Interleukin-10 (Am0010) in Patients with Advanced Solid Tumors (2016) Naing A, Papadopoulos KP, Autio KA, Ott PA, Patel MR, Wong DJ, Falchook GS, Pant S, Whiteside M, Rasco DR, Mumm JB, Chan IH, Bendell JC, Bauer TM, Colen RR, Hong DS, Van Vlasselaer P, Tannir NM, Oft M, Infante JR Journal of Clinical Oncology
Altered Cerebrospinal Fluid Proteins in Smith–Lemli– (2016) Cologna SM, Shieh C, Toth CL, Cougnoux A, Burkert KR, Bianconi SE, Wassif CA, Porter FD American Journal of Medical Genetics Part A
Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses (2016) Urrutia A, Duffy D, Rouilly V, Posseme C, Djebali R, Illanes G, Libri V, Albaud B, Gentien D, Piasecka B, Hasan M, Fontes M, Quintana-Murci L, Albert Matthew l, Abel L, Alcover A, Astrom K, Bousso P, Bruhns P, Cumano A, Demangel C, Deriano L, Di santo J, Dromer F, Eberl G, Enninga J, Fellay J, Freitas A, Gelpi O, Gomperts-Boneca I, Hercberg S, Lantz O, Leclerc C, Mouquet H, Pellegrini S, Pol S, Rogge L, Sakuntabhai A, Schwartz O, Schwikowski B, Shorte S, Soumelis V, Tangy F, Tartour E, Toubert A, Ungeheuer M-N, Quintana-Murci L, Albert Matthew Cell Reports
Predictors of Asthma Following Severe Respiratory Syncytial Virus (Rsv) Bronchiolitis in Early Childhood (2016) Lu S, Hartert TV, Everard ML, Giezek H, Nelsen L, Mehta A, Patel H, Knorr B, Reiss TF Pediatric Pulmonology
Blood-based immune-endocrine biomarkers of treatment response in depression (2016) Chan MK, Cooper JD, Bot M, Birkenhanger TK, Bergink V, Drexhage HA, Steiner J, Rothermundt M, Penninx BWJH, Bahn S Journal of Psychiatric Research
Effects of Repeated Complement Activation Associated with Chronic Treatment of Cynomolgus Monkeys with 2'-O-Methoxyethyl Modified Antisense Oligonucleotide (2016) Shen L, Engelhardt JA, Hung G, Yee J, Kikkawa R, Matson J, Tayefeh B, Machemer T, Giclas PC, Henry SP Nucleic Acid Therapeutics
Towards a Blood-Based Diagnostic Panel for Bipolar Disorder (2016) Haenisch F, Cooper JD, Reif A, Kittel-Schneider S, Steiner J, Leweke FM, Rothermundt M, Van Beveren NJM, Crespo-Facorro B, Niebuhr DW, Cowan DN, Weber NS, Yolken RH, Penninx BWJH, Bahn S Brain, Behavior, and Immunity
The Different Effects of Strength and Endurance Exercise Training on Cox-2 and Mpges-Expression in Mouse Brain Are Independent of Peripheral Inflammation (2016) Krüger K, Bredehöft J, Mooren FC, Rummel C Journal of Applied Physiology
Phase 1 study of the anti-vascular endothelial growth factor receptor 3 monoclonal antibody LY3022856/IMC-3C5 in patients with advanced and refractory solid tumors and advanced colorectal cancer (2016) Saif MW, Knost JA, Chiorean EG, Kambhampati SR, Yu D, Pytowski B, Qin A, Kauh JS, O'Neil BH Cancer Chemother Pharmacol
Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant (2016) Felsky D, De Jager PL, Schneider JA, Arfanakis K, Fleischman DA, Arvanitakis Z, Honer WG, Pouget JG, Mizrahi R, Pollock BG, Kennedy JL, Bennett DA, Voineskos AN J Cereb Blood Flow Metab
Type I Ifns Regulate Inflammation, Vasculopathy, and Fibrosis in Chronic Cutaneous Graft-Versus-Host Disease (2016) Delaney TA, Morehouse C, Brohawn PZ, Groves C, Colonna M, Yao, Y, Sanjuan M, Coyle AJ The Journal of Immunology
Variation in Serum Biomarkers with Sex and Female Hormonal Status: Implications for Clinical Tests (2016) Ramsey JM, Cooper JD, Penninx BWJH, Bahn S Scientific Reports
Plasma cystatin C and neutrophil gelatinase-associated lipocalin in relation to coronary atherosclerosis on intravascular ultrasound and cardiovascular outcome: Impact of kidney function (ATHEROREMO-IVUS study). (2016) Brankovic M, Akkerhuis KM, Buljubasic N, Cheng JM, Oemrawsingh RM, Garcia-Garcia HM, Regar E, Serruys PW, van Geuns RJ, Boersma E, Kardys I. Atherosclerosis
Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits (2016) Deming Y, Xia J, Cai Y, Lord J, Del-Aguila JL, Fernandez MV, Carrell D, Black K, Budde J, Ma S, Saef B, Howells B, Bertelsen S, Bailey M, Ridge PG, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Holtzman D, Morris JC, Bales K, Pickering EH, Lee J, Heitsch L, Kauwe J, Goate A, Piccio L, Cruchaga C Scientific Reports
Inflammatory Profile in Lrrk2-Associated Prodromal and Clinical Pd (2016) Brockmann K, Apel A, Schulte C, Schneiderhan-Marra N, Pont-Sunyer C, Vilas D, Ruiz-Martinez J, Langkamp M, Corvol J-C, Cormier F, Knorpp T, Joos TO, Gasser T, Schüle B, Aasly JO, Foroud T, Marti-Masso JF, Brice A, Tolosa E, Marras C, Berg D, Maetzler W Journal of Neuroinflammation
Enhanced Molecular Aging in Late-Life Depression: the Senescent Associated Secretory Phenotype (2016) Diniz BS, Reynolds III CF, Sibille E, Lin C, Tseng G, Lotrich F, Aizenstein HJ, Butters MA The American Journal of Geriatric Psychiatry
Pre-vaccination inflammation and B-cell signalling predict age-related hyporesponse to hepatitis B vaccination (2016) Fourati S, Cristescu R, Loboda A, Talla A, Filali A, Railkar R, Schaeffer AK, Favre D, Gagnon D, Peretz Y, Wang IM, Beals CR, Casimiro DR, Carayannopoulos LN, Sékaly RP Nat Commun. 2016 Jan 8;7:10369
Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma (2016) Choueiri TK, Fishman M, Escudier B, McDermott DF, Drake CG, Kluger HM, Stadler WM, Perez-Gracia JL, McNeel DG, Curti BD, Harrison MR, Plimack ER, Appleman L, Fong L, Albiges L, Cohen LJ, Young TC, Chasalow SD, Ross-MacDonald P, Srivastava S, Jure-Kunkel M, Kurland JF, Simon JS, Sznol M Clinical Cancer Research
Behavioural Traits Propagate across Generations Via Segregated Iterative-Somatic and Gametic Epigenetic Mechanisms (2016) Mitchell E, Klein SL, Argyropoulos KV, Sharma A, Chan RB, Toth JG, Barboza L, Bavley C, Bortolozzi A, Chen Q, Liu B, Ingenito J, Mark W, Dudakov J, Gross S, Di Paolo G, Artigas F, Van Den Brink M, Toth M Nature Communications
Pathogen and Host Response Dynamics in a Mouse Model of Borrelia hermsii Relapsing Fever (2016) Crowder CD, Langeroudi AG, Estabragh AS, Lewis ERG, Marcsisin RA, Barbour AG Veterinary Sciences
A Randomized Trial Evaluating Various Administration Routes of Natalizumab in Multiple Sclerosis (2016) Plavina T, Fox EJ, Lucas N, Muralidharan KK, Mikol D J Clin Pharmacol
Amyloid Proteotoxicity Initiates an Inflammatory Response Blocked by Cannabinoids (2016) Currais A, Quehenberger O, Armando AM, Daugherty D, Maher P, Schubert D NPJ Aging and Mechanisms of Disease
Biomarkers Predictive of Exacerbations in the SPIROMICS and COPDGene Cohorts. (2016) Keene JD, Jacobson S, Kechris K, Kinney GL, Foreman MG, Doerschuk CM, Make BJ, Curtis JL, Rennard SI, Barr RG, Bleecker ER, Kanner RE, Kleerup EC, Hansel NN, Woodruff PG, Han MK, Paine Iii R, Martinez FJ, Bowler RP, O'Neal WK; for COPDGene and SPIROMICS Investigators. Am J Respir Crit Care Med.
Baseline results of the NeuroNEXT spinal muscular atrophy infant biomarker study (2016) Kolb SJ, Coffey CS, Yankey JW, Krosschell K, Arnold WD, Rutkove SB, Swoboda KJ, Reyna SP, Sakonju A, Darras BT, Shell R, Kuntz N, Castro D, Iannaccone ST, Parsons J, Connolly AM, Chiriboga CA, McDonald C, Burnette WB, Werner K, Thangarajh M, Shieh PB, Finanger E, Cudkowicz ME, McGovern MM, McNeil DE, Finkel R, Kaye E, Kingsley A, Renusch SR, McGovern VL, Wang X, Zaworski PG, Prior TW, Burghes AH, Bartlett A, Kissel JT Ann Clin Transl Neurol
Tenascin-C drives persistence of organ fibrosis (2016) Bhattacharyya S, Wang W, Morales-Nebreda L, Feng G, Wu M, Zhou X, Lafyatis R, Lee J, Hinchcliff M, Feghali-Bostwick C, Lakota K, Budinger GRS, Raparia K, Tamaki Z, Varga J Nature Communications
A phase 2 study of dalantercept, an activin receptor-like kinase-1 ligand trap, in patients with recurrent or metastatic squamous cell carcinoma of the head and neck. (2016) Jimeno A, Posner MR, Wirth LJ, Saba NF, Cohen RB, Popa EC, Argiris A, Grossmann KF, Sukari A, Wilson D, Zhang X, Sun J, Glasser C, Attie KM, Sherman ML, Pandya SS, Weiss J. Cancer
Serum apolipoprotein E is associated with long-term risk of Alzheimer's disease: the Rotterdam Study (2016) Wolters FJ, Koudstaal PJ, Hofman A, Duijn CM, Ikram MA. Neurosci Lett
Plasma proteomics in CML patients before and after initiation of tyrosine kinase inhibitor therapy reveals induced Th1 immunity and loss of angiogenic stimuli. (2016) Söderlund S, Christiansson L, Persson I, Hjorth-Hansen H, Richter J, Simonsson B, Mustjoki S, Olsson-Strömberg U, Loskog A. Leuk Res
Predicting Progression from Mild Cognitive Impairment to Alzheimer's Dementia Using Clinical, MRI, and Plasma Biomarkers via Probabilistic Pattern Classification (2016) Korolev IO, Symonds LL, Bozoki AC; Alzheimer's Disease Neuroimaging Initiative PLoS One
Endometriosis Leads to an Increased Trefoil Factor 3 Concentration in the Peritoneal Cavity but Does Not Alter Systemic Levels (2016) Henze D, Doecke W-D, Hornung D, Agueusop I, Von Ahsen O, Machens K, Schmitz AA, Gashaw I Reproductive Sciences
Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis. (2016) Amalakuhan B, Habib SA, Mangat M, Reyes LF, Rodriguez AH, Hinojosa CA, Soni NJ, Gilley RP, Bustamante CA, Anzueto A, Levine SM, Peters JI, Aliberti S, Sibila O, Chalmers JD, Torres A, Waterer GW, Martin-Loeches I, Bordon J, Blanquer J, Sanz F, Marcos PJ, Rello J, Ramirez J, Solé-Violán J, Luna CM, Feldman C, Witzenrath M, Wunderink RG, Stolz D, Wiemken TL, Shindo Y, Dela Cruz CS, Orihuela CJ, Restrepo MI. Cytokine
Dynamic Macrophage Polarization-Specific miRNA Patterns Reveal Increased Soluble VEGF Receptor 1 by miR-125a-5p Inhibition. (2016) Melton DW, Lei XF, Gelfond JAL, Shireman PK Physiological Genomics
Do Single or Sequential Measurements of Leptin and Adiponectin in Plasma Have Prognostic Value in Pulmonary Arterial Hypertension? (2016) Tonelli AR, Fares WH, Dakkak W, Rao Y, Dweik RA Pulmonary Circulation
Roflumilast combined with montelukast versus montelukast alone as add-on treatment in patients with moderate-to-severe asthma (2016) Bateman ED, Goehring UM, Richard F, Watz H Journal of Allergy and Clinical Immunology
Comprehensive Systems Biology Analysis of a 7-Month Cigarette Smoke Inhalation Study in C57bl/6 (2016) Ansari S, Baumer K, Boué S, Dijon S, Dulize R, Ekroos K, Elamin A, Foong C, Guedj E, Hoeng J, Ivanov NV, Krishnan S, Leroy P, Martin F, Merg C, Peck MJ, Peitsch MC, Phillips B, Schlage WK, Schneider T, Talikka M, Titz B, Vanscheeuwijck P, Veljkovic E, Vihervaara T, Vuillaume G, Woon CQ Scientific Data
Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with cigarette smoke (2016) Wong ET, Kogel U, Veljkovic E, Martin F, Xiang Y, Boue S, Vuillaume G, Leroy P, Guedj E, Rodrigo G, Ivanov NV, Hoeng J, Peitsch MC, Vanscheeuwijck P. Regul Toxicol Pharmacol.
Coordinated Activation of Toll-Like Receptor8 (TLR8) and NLRP3 by the TLR8 Agonist, VTX-2337, Ignites Tumoricidal Natural Killer Cell Activity (2016) Dietsch GN, Lu H, Yang Y, Morishima C, Chow LQ, Disis ML, Hershberg RM PLoS ONE
A Potential Endophenotype for Alzheimer's Disease: Cerebrospinal Fluid Clusterin (2016) Deming Y, Xia J, Cai Y, Lord J, Holmans P, Bertelsen S, Holtzman D, Morris JC, Bales K, Pickering EH, Kauwe J, Goate A, Cruchaga C Neurobiology of Aging
Primary Analysis Of A Phase II Open-Label Trial Of INCB039110, A Selective JAK1 Inhibitor, In Patients With Myelofibrosis (2016) Mascarenhas JO, Talpaz M, Gupta V, Foltz LM, Savona MR, Paquette R, Turner AR, Coughlin P, Winton E, Burn TC, O'Neill P, Clark J, Hunter D10, Assad A, Hoffman R, Verstovsek S Haematologica
2. Plasma insulin-like growth factor I levels are higher in depressive and anxiety disorders, but lower in antidepressant medication users (2016) Bot M, Milaneschi Y, Penninx BWJH, Drent ML Psychoneuroendocrinology
Biological stress systems, adverse life events and the improvement of chronic multi-site musculoskeletal pain across a 6-year follow-up. (2016) Generaal E, Vogelzangs N, Macfarlane GJ, Geenen R, Smit JH, de Geus EJ, Dekker J, Penninx BW. J Pain
1. Macrophage Galactose-Type Lectin-1 Deficiency Is Associated with Increased Neutrophilia and Hyperinflammation in Gram-Negative Pneumonia (2016) Jondle CN, Sharma A, Simonson TJ, Larson B, Mishra BB, Sharma J Journal of Immunology
Evaluation of the Tobacco Heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a mentholated version compared with mentholated and non-mentholated cigarette smoke (2016) Oviedo A, Lebrun S, Kogel U, Ho J, Tan WT, Titz B, Leroy P, Vuillaume G, Bera M, Martin F, Rodrigo G, Esposito M, Dempsey R, Ivanov NV, Hoeng J, Peitsch MC, Vanscheeuwijck P. Regul Toxicol Pharmacol.
Biomarkers in Rheumatoid Arthritis, what is new? (2016) Gavrila BI, Ciofu C, and Stoica V J Med Life
Thrombopoietin is associated with d's intercept, and only in Non-Hispanic Whites (2016) Royall DR, Palmer RF Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
Insulin-like growth factor binding protein-2 interactions with Alzheimer's disease biomarkers. (2016) Lane EM, Hohman TJ, Jefferson AL; Alzheimer’s Disease Neuroimaging Initiative. Brain Imaging Behav
Association of the multi-biomarker disease activity score with joint destruction in patients with rheumatoid arthritis receiving tumor necrosis factor-alpha inhibitor treatment in clinical practice (2016) Hirata S, Li W, Kubo S, Fukuyo S, Mizuno Y, Hanami K, Sawamukai N, Yamaoka K, Saito K, Defranoux NA, Tanaka Y Mod Rheumatol
The dipeptidyl peptidase inhibitor linagliptin and the angiotensin II receptor blocker telmisartan show renal benefit by different pathways in rats with 5/6 nephrectomy (2016) Tsuprykov O, Ando R, Reichetzeder C, von Websky K, Antonenko V, Sharkovska Y, Chaykovska L, Rahnenführer J, Hasan AA, Tammen H, Alter M, Klein T, Ueda S, Yamagishi S, Okuda S, Hocher B Kidney International
Selective p38a MAP kinase/MAPK14 inhibition in enzymatically-modified LDL-stimulated human monocytes: implications for atherosclerosis. (2016) Cheng F, Twardowski L, Fehr S, Aner C, Schaeffeler E, Joos T, Knorpp T, Dorweiler B, Laufer S, Schwab M, Torzewski M. FASEB J
Association of a multibiomarker disease activity score at multiple time-points with radiographic progression in rheumatoid arthritis: results from the SWEFOT trial (2016) Hambardzumyan K, Bolce RJ, Saevarsdottir S, Forslind K, Wallman JK, Cruickshank SE, Sasso E, Chernoff D and Van Vollenhoven R RMD
Immune Monitoring Technology Primer: Immunoprofiling of Antigen-Stimulated Blood (2016) Brunet LR, LaBrie S, Hagemann T Journal for Immunotherapy of Cancer
Least absolute shrinkage and selection operator type methods for the identification of serum biomarkers of overweight and obesity: simulation and application. (2016) Vasquez MM, Hu C, Roe DJ, Chen Z, Halonen M, Guerra S BMC Med Res Methodol
System-Based Proteomic and Metabonomic Analysis of the Df(16)a+/- Mouse Identifies Potential Mir-185 Targets and Molecular Pathway Alterations (2016) Wesseling H, Xu B, Want EJ, Holmes E, Guest PC, Karayiorgou M, Gogos JA, Bahn S Molecular Psychiatry
A Sputum Proteomic Signature That Associates with Increased Il-1? Levels and Bacterial Exacerbations of COPD (2016) Damera G, Pham T-H, Zhang J, Ward CK, Newbold P, Ranade K, Sethi S Lung
The Relationship between Complement Factor C3, Apoe ?4, Amyloid and Tau in Alzheimer’s Disease (2016) Bonham LW, Desikan RS, Yokoyama JS Acta Neuropathologica Communications
Investigative Nonclinical Cardiovascular Safety and Toxicology Studies with BMS-986094, an NS5b RNA-Dependent RNA Polymerase Inhibitor (2016) Gill M, Horn K, Hennan J, White R, Bounous D, Clark S, Megill JR, Janovitz E, Davies M, Sanderson T, Graziano M. Toxicol Sci
Evaluation of Novel Biomarkers of Nephrotoxicity in Cynomolgus Monkeys Treated with Gentamicin (2016) Gautier J-C, Zhou X, Yang Y, Gury T, Qu Z, Palazzi X, Léonard J-F, Slaoui M, Veeranagouda Y, Guizon I, Boitier E, Filali-Ansary A, van den Berg BHJ, Poetz O, Joos T, Zhang T, Wang J, Detilleux P, Li B Toxicology and Applied Pharmacology
Variants in Ccl16 Are Associated with Blood Plasma and Cerebrospinal Fluid Ccl16 Protein Levels (2016) Ebbert MTW, Staley LA, Parker J, Parker S, Bailey M, Ridge PG, Goate AM, Kauwe JSK BMC Genomics
Social status alters immune regulation and response to infection in macaques (2016) Snyder-Mackler N, Sanz J, Kohn JN, Brinkworth JF, Morrow S, Shaver AO, Grenier JC, Pique-Regi R, Johnson ZP, Wilson ME, Barreiro LB, Tung J Science
Noninvasive Transcutaneous Vagus Nerve Stimulation Decreases Whole Blood Culture-Derived Cytokines and Chemokines: A Randomized, Blinded, Healthy Control Pilot Trial (2016) Lerman I, Hauger R, Sorkin L, Proudfoot J, Davis B, Huang A, Lam K, Simon B, Baker DG Neuromodulation: Technology at the Neural Interface
Blood Biomarkers of Chronic Inflammation in Gulf War Illness (2016) Johnson GJ, Slater BCS, Leis LA, Rector TS, Bach RR PLoS ONE
Exercise-induced cytokine changes in antigen stimulated whole-blood cultures compared to serum (2016) Pilat C, Krüger K, Frech T, Mooren FC J Immunol Methods.
Plasma Egf and Cognitive Decline in Parkinson's Disease and Alzheimer's Disease (2016) Lim NS, Swanson CR, Cherng H-R, Unger TL, Xie SX, Weintraub D, Marek K, Stern MB, Siderowf A, Pars Investigators, Alzheimer's Disease Neuroimaging Initiative, Trojanowski JQ, Chen-Plotkin AS Annals of Clinical and Translational Neurology
Sjögren’s Syndrome Patients with Ectopic Germinal Centers Present with a Distinct Salivary Proteome (2016) Delaleu N, Mydel P, Brun JG, Jonsson MV, Alimonti A, Jonsson R Rheumatology
Identification of Plexin A4 as a Novel Clusterin Receptor Links Two Alzheimer's Disease Risk Genes (2016) Kang SS, Kurti A, Wojtas A, Baker KE, Liu CC, Kanekiyo T, Deming Y, Cruchaga C, Estus S, Bu G, Fryer JD Human Molecular Genetics
Oxidative stress in drug-naïve first episode patients with schizophrenia and major depression: effects of disease acuity and potential confounders (2016) Jordan W, Dobrowolny H, Bahn S, Bernstein HG, Brigadski T Eur Arch Psychiatry Clin Neurosci
Effect of Low-Magnitude, High-Frequency Mechanical Stimulation on Bmd among Young Childhood Cancer Survivors: A Randomized Clinical Trial (2016) Mogil RJ, Kaste SC, Ferry Jr RJ, Hudson MM, Mulrooney DA, Howell CR, Partin RE, Srivastava DK, Robison LL, Ness KK JAMA Oncology
Vagus Nerve Stimulation Inhibits Cytokine Production and Attenuates Disease Severity in Rheumatoid Arthritis (2016) Koopman FA, Chavan SS, Miljko S, Grazio S, Sokolovic S, Schuurman PR, Mehta AD, Levine YA, Faltys M, Zitnik R, Tracey KJ, Tak PP PNAS
Serum protein mediators of dementia and aging proper (2016) Royall DR, Al-Rubaye S, Bishnoi R, Palmer RF Aging
A Novel Approach for Emerging and Antibiotic Resistant Infections: Innate Defense Regulators as an Agnostic Therapy (2016) North JR, Takenaka S, Rozek A, Kielczewska A, Opal S, Morici LA, Finlay BB, Schaber CJ, Straube R, Donini O Journal of Biotechnology
Effects of Traumeel (Tr14) on Exercise-Induced Muscle Damage Response in Healthy Subjects: A Double-Blind RCT (2016) Muders K, Pilat C, Deuster V, Frech T, Kruger K, Pons-Kuhnemann J, Mooren F-C Mediators of Inflammation
Pentraxin-2 suppresses c-Jun/AP-1 signaling to inhibit progressive fibrotic disease (2016) Nakagawa N, Barron L, Gomez IG, Johnson BG, Roach AM, Kameoka S, Jack RM, Lupher ML, Gharib SA, Duffield JS JCI Insight
Apolipoprotein a-I and Paraoxonase-1 Are Potential Blood Biomarkers for Ischemic Stroke Diagnosis (2016) Walsh KB, Hart K, Roll S, Sperling M, Unruh D, Davidson WS, Lindsell CJ, Adeoye O Journal of Stroke and Cerebrovascular Diseases
Characterizing the Inflammatory Response in Esophageal Mucosal Biopsies in Children with Eosinophilic Esophagitis (2016) Sayej WN, Menoret A, Maharjan AS, Fernandez M, Wang Z, Balarezo F, Hyams JS, Sylvester FA, Vella AT Clinical & Translational Immunology
Growth Differentiation Factor 15 as a Novel Biomarker for Metformin (2016) Gerstein HC, Pare G, Hess S, Ford RJ, Sjaarda J, Raman K, McQueen M, Lee S, Haenel H, Steinberg GR; ORIGIN Investigators. Diabetes Care
Genome-Wide Association Study of Prolactin Levels in Blood Plasma and Cerebrospinal Fluid (2016) Staley LA, Ebbert MTW, Parker S, Bailey M, Ridge PG, Goate AM, Kauwe JSK BMC Genomics
Mindfulness-Based Cognitive Therapy Associated with Decreases in C-Reactive Protein in Major Depressive Disorder: A Pilot Study (2016) Eisendrath SJ, Gillung E, Hartzler A, James-Myers M, Wolkowitz O, Sipe W, Ramanatham D, Delucchi K J. Altern. Complement. Med.
High false-positive rate of a putative biomarker test to aid in the diagnosis of schizophrenia (2016) Wehler CA, Preskorn, SH Journal of Clinical Psychiatry
A Semi-Mechanism Approach Based on Mri and Proteomics for Prediction of Conversion from Mild Cognitive Impairment to Alzheimer’s Disease (2016) Liu H, Zhou X, Jiang H, He H, Liu X Scientific Reports
Serum Proteomic Profiles of Depressive Subtypes (2016) Lamers F, Bot M, Jansen R, Chan MK, Cooper JD, Bahn S, Penninx BWJH Translational Psychiatry
Serum biomarkers and changes in clinical/MRI evidence of golimumab-treated patients with ankylosing spondylitis: results of the randomized, placebo-controlled GO-RAISE study (2016) Inman RD, Baraliakos X, Hermann KA, Braun J, Deodhar A, Heijde D, Xu S, and Hsu B Arthritis Res Ther.
A multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of treatment with sirukumab (CNTO 136) in patients with active lupus nephritis (2016) Rovin B, van Vollenhoven R, Aranow C, Wagner C, Gordon R, Zhuang Y, Belkowski S, Hsu B Arthritis & Rheumatology
Circulating Biomarkers and Outcome from a Randomised Phase Ii Trial of Sunitinib Vs Everolimus for Patients with Metastatic Renal Cell Carcinoma (2016) Voss MH, Chen D, Marker M, Hakimi AA, Lee C-H, Hsieh JJ, Knox JJ, Voi M, Motzer RJ British Journal of Cancer
Early Role of Vascular Dysregulation on Late-Onset Alzheimer's Disease Based on Multifactorial Data-Driven Analysis (2016) Iturria-Medina Y, Sotero RC, Toussaint PJ, Mateos-Perez JM, Evans AC, The Alzheimer's Disease Neuroimaging Initiative Nature Communications
Peripheral Blood Cell Gene Expression Diagnostic for Identigying Symptomatic Transthyretin Amyloidosis Patients: Male and Female Specific Signatures (2016) Kurian SM, Novais M, Whisenant T, Gelbart T, Buxbaum JN, Kelly JW, Coelho T, Salomon DR Theranostics
Serum Levels of Apolipoproteins and Incident Type 2 Diabetes: A Prospective Cohort Study (2016) Brahimaj A, Ligthart S, Ikram MA, Hofman A, Franco OH, Sijbrands EJ, Kavousi M, Dehghan A Diabetes Care
Cytokine Production Capacity in Depression and Anxiety (2016) Vogelzangs N, De Jonge P, Smit JH, Bahn S, Penninx BW Translational Psychiatry
Loss of Immune Tolerance Is Controlled by Icos in Sle1 Mice (2016) Mittereder N, Kuta E, Bhat G, Dacosta K, Cheng LI, Herbst R, Carlesso G Journal of Immunology
Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children (2016) Stein MM, Hrusch CL, Gozdz J, Igartua C, Pivniouk V, Murray SE, Ledford JG, Marques Dos Santos M, Anderson RL, Metwali N, Neilson JW, Maier RM, Gilbert JA, Holbreich M, Thorne PS, Martinez FD, Von Mutius E, Vercelli D, Ober C, Sperling AI New England Journal of Medicine
Differential expression of P2X7 receptor and IL-1ß in nociceptive and neuropathic pain. (2016) Luchting B, Heyn J, Woehrle T, Rachinger-Adam B, Kreth S, Hinske LC, Azad SC J Neuroinflammation
Effects of Acute Endurance Exercise on Plasma Protein Profiles of Endurance-Trained and Untrained Individuals over Time (2016) Schild M, Eichner G, Beiter T, Zuegel M, Niess AM, Steinacker JM, Mooren FC Mediators of Inflammation
Contribution of Staphylococcus Aureus Coagulases and Clumping Factor a to Abscess Formation in a Rabbit Model of Skin and Soft Tissue Infection (2016) Malachowa N, Kobayashi SD, Porter AR, Braughton KR, Scott DP, Gardner DJ, Missiakas DM, Schneewind O, Deleo FR PLoS ONE
Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD (2016) Sun W, Kechris K, Jacobson S, Drummond MB, Hawkins GA, Yang J, Chen T-H, Quibrera PM, Anderson W, Barr RG, Basta PV, Bleecker ER, Beaty T, Casaburi R, Castaldi P, Cho MH, Comellas A, Crapo JD, Criner G, Demeo D, Christenson SA, Couper DJ, Curtis JL, Doerschuk CM, Freeman CM, Gouskova NA, Han MK, Hanania NA, Hansel NN, Hersh CP, Hoffman EA, Kaner RJ, Kanner RE, Kleerup EC, Lutz S, Martinez FJ, Meyers DA, Peters SP, Regan EA, Rennard SI, Scholand MB, Silverman EK, Woodruff PG, O’neal WK, Bowler RP, Group SR, Investigators CO PLOS Genetics
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2015
Plasma BDNF levels associate with Pittsburgh Compound B binding in the brain. (2015) Hwang KS, Lazaris AS, Eastman JA, Teng E, Thompson PM, Gylys KH, Cole GM, Apostolova LG, for the Alzheimers Dement (Amst) 2015 Apr 22. [Epub ahead of print]
A Subset of Cerebrospinal Fluid Proteins from a Multi-Analyte Panel Associated with Brain Atrophy, Disease Classification and Prediction in Alzheimer's Disease. (2015) Khan W, Aguilar C, Kiddle SJ, Doyle O, Thambisetty M, Muehlboeck S, Sattlecker M, Newhouse S, Lovestone S, Dobson R, Giampietro V, Westman E, Simmons A PLoS One
Feasibility of investigating differential proteomic expression in depression: implications for biomarker development in mood disorders (2015) Frye MA, Nassan M, Jenkins GD, Kung S, Veldic M, Palmer BA, Feeder SE, Tye SJ, Choi DS and Biernacka HM Translational Psychiatry
Development of a Blood-Based Molecular Biomarker Test for Identification of Schizophrenia before Disease Onset (2015) Chan MK, Krebs MO, Cox D, Guest PC, Yolken RH, Rahmoune H, Rothermundt M, Steiner J, Leweke FM, Van Beveren NJM, Niebuhr DW, Weber NS, Cowan DN, Suarez-Pinilla P, Crespo-Facorro B, Mam-Lam-Fook C, Bourgin J, Wenstrup RJ, Kaldate RR, Cooper JD, Bahn S Translational Psychiatry
Biological stress systems, adverse life events and the onset of chronic multisite musculoskeletal pain: a 6-year cohort study. (2015) Generaal E, Vogelzangs N, Macfarlane GJ, Geenen R, Smit JH, de Geus EJ, Penninx BW, Dekker J. Ann Rheum Dis. 2015 Apr 22. pii: annrheumdis-2014-206741. doi: 10.1136/annrheumdis-2014-206741. [Epub ahead of print]
Multianalyte markers of schizophrenia and bipolar disorder: A preliminary study. (2015) Dickerson F, Schroeder J, Stallings C, Origoni A, Bahn S, Yolken R Schizophr Res.
Prognostic and predictive biomarkers of AAA growth rate. (2015) Deeg MA, Meijer CA, Chan LS, Shen L, Lindeman JH. Curr Med Res Opin
Progressive Reduction in Cortical Thickness as Psychosis Develops: A Multisite Longitudinal Neuroimaging Study of Youth at Elevated Clinical Risk (2015) Cannon TD, Chung Y, He G, Sun D, Jacobson A, Van Erp TGM, Mcewen S, Addington J, Bearden CE, Cadenhead K, Cornblatt B, Mathalon DH, Mcglashan T, Perkins D, Jeffries C, Seidman LJ, Tsuang M, Walker E, Woods SW, Heinssen R Biological Psychiatry
Bone Marrow from Blotchy Mice Is Dispensable to Regulate Blood Copper and Aortic Pathologies but Required for Inflammatory Mediator Production in Ldlr-Deficient Mice During Chronic Angiotensin Ii Infusion (2015) Harris D, Liang Y, Chen C, Li S, Patel O, Qin Z Annals of Vascular Surgery
CHOP Links Endoplasmic Reticulum Stress to NF-kB Activation in the Pathogenesis of Nonalcoholic Steatohepatitis. (2015) Willy JA, Young SK, Stevens JL, Masuoka HC, Wek RC. Mol Biol Cell. 2015 Apr 22. pii: mbc.E15-01-0036. [Epub ahead of print]
PA401, a novel CXCL8-based biologic therapeutic with increased glycosaminoglycan binding, reduces bronchoalveolar lavage neutrophils and systemic inflammatory markers in a murine model of LPS-induced lung inflammation. (2015) Adage T, Del Bene F, Fiorentini F, Doornbos RP, Zankl C, Bartley MR, Kungl AJ Cytokine
Self-reactive IgE exacerbates interferon responses associated with autoimmunity (2015) Henault J, Riggs JM, Karnell JL, Liarski VM, Li J, Shirinian L, Xu L, Casey KA, Smith MA, Khatry DB, Izhak L, Clarke L, Herbst R, Ettinger R, Petri M, Clark MR, Mustelin T, Kolbeck R, Sanjuan MA Nat Immunol.
Discovery of serum biomarkers predicting development of a subsequent depressive episode in social anxiety disorder. (2015) Gottschalk MG, Cooper JD, Chan MK, Bot M, Penninx BW, Bahn S. Brain Behav Immun. 2015 Apr 28. pii: S0889-1591(15)00118-X. doi: 10.1016/j.bbi.2015.04.011. [Epub ahead of print]
Toxicity of aerosols of nicotine and pyruvic acid (separate and combined) in Sprague–Dawley rats in a 28-day OECD 412 inhalation study and assessment of systems toxicology (2015) Phillips B, Esposito M, Verbeeck J, Boué S, Iskandar A, Vuillaume G, Leroy P, Krishnan S, Kogel U, Utan A, Schlage WK, Bera M, Veljkovic E, Hoeng J, Peitsch MC, Vanscheeuwijck P Inhal Toxicol.
Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges (2015) O'Bryant SE, Listac S, Rissman RA, Edwards M, Zhang F, Hall J, Zetterberg H, Lovestone S, Gupta V, Graff-Radford N, Martins R, Jeromin A, Waring S, Oh E, King M, Baker L, Hampel H Alzheimers Dement (2015) 1-8
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The Pharmacodynamic Impact of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, on Circulating Levels of Inflammatory Biomarkers in Patients with Psoriatic Arthritis: Substudy Results From a Phase 3, Randomized, Placebo-Controlled Trial (PALACE 1). (2015) Schafer P, Chen P, Fang L, Wang A, Chopra R. J Immunol Res 2015 Jan 10 [Epub ahead of print]
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A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression (2015) Cho HS, Shin HM, Haberstock-Debic H, Xing Y, Owens TD, Funk JO, Hill RJ, Bradshaw JM, Berg LJ J Immunol.
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Responses to Bacteria, Virus and Malaria Distinguish the Etiology of Pediatric Clinical Pneumonia (2015) Valim C, Ahmad R, Lanaspa M, Tan Y, Acácio S, Gillette MA, Almendinger KD, Milner DA Jr, Madrid L, Pellé K, Harezlak J, Silterra J, Alonso PL, Carr SA, Mesirov JP, Wirth DF, Wiegand RC, Bassat Q Am J Respir Crit Care Med.
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Suppression of T Cell Activation and Collagen Accumulation by an Anti-Type I Interferon Receptor Monoclonal Antibody in Adult Patients with Systemic Sclerosis. (2015) Guo X, Higgs BW, Bay-Jensen AC, Karsdal MA, Yao Y, Roskos LK, White WI. J Invest Dermatol. 2015 May 20. doi: 10.1038/jid.2015.188. [Epub ahead of print]
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A Phase I/Ii Trial of Bnc105p with Everolimus in Metastatic Renal Cell Carcinoma (2015) Pal S, Azad A, Bhatia S, Drabkin H, Costello B, Sarantopoulos J, Kanesvaran R, Lauer R, Starodub A, Hauke R, Sweeney CJ, Hahn NM, Sonpavde G, Richey S, Breen T, Kremmidiotis G, Leske A, Doolin E, Bibby DC, Simpson J, Iglesias J, Hutson T Clinical Cancer Research
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Plasma Inflammatory Factors Are Associated with Anxiety, Depression, and Cognitive Problems in Adults with and without Methamphetamine Dependence: An Exploratory Protein Array Study (2015) Huckans M, Fuller BE, Chalker ALN, Adams M, Loftis JM Frontiers in Psychiatry
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Phase II Evaluation of IPI-926, an Oral Hedgehog Inhibitor, in Patients with Myelofibrosis. (2015) Sasaki K, Gotlib JR, Mesa RA, Newberry KJ, Ravandi F, Cortes JE, Kelly P, Kutok JL, Kantarjian HM, Verstovsek S. Leuk Lymphoma. 2015 Feb 2:1-20. [Epub ahead of print]
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Time Course of Cigarette Smoke-Induced Changes of Systemic Inflammation and Muscle Structure (2015) Krüger K, Dischereit G, Seimetz M, Wilhelm J, Weissmann N, Mooren FC American Journal of Physiology - Lung Cellular and Molecular Physiology
Multibiomarker disease activity score and C-reactive protein in a cross-sectional observational study of patients with rheumatoid arthritis with and without concomitant fibromyalgia (2015) Lee YC, Hackett J, Frits M, Iannaccone C, Shadick N, Weinblatt M, Segurado O and Sasso E Rheumatology
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Plasma Angiopoietin-2 Outperforms Other Markers of Endothelial Injury in Prognosticating Pediatric ARDS Mortality (2015) Zinter MS, Spicer A, Orwoll BO, Alkhouli M, Dvorak CC, Calfee CS, Matthay MA, Sapru A American Journal of Physiology - Lung Cellular and Molecular Physiology
Enhancement of Patient Recruitment in Rheumatoid Arthritis Clinical Trials Using a Multi-Biomarker Disease Activity Score as an Inclusion Criterion (2015) Van Vollenhoven R, Bolce R, Hambardzumyan K, Saevarsdottir S, Forslind K, Petersson I, Sasso E, Hwang C, Segurado O, and Geborek P Arthritis & Rheumatol
Protein biomarkers for the prediction of cardiovascular disease in type 2 diabetes. (2015) Looker HC, Colombo M, Agakov F, Zeller T, Groop L, Thorand B, Palmer CN, Hamsten A, de Faire U, Nogoceke E, Livingstone SJ, Salomaa V, Leander K, Barbarini N, Bellazzi R, van Zuydam N, McKeigue PM, Colhoun HM; on behalf of the SUMMIT Investigators. Diabetologia. 2015 Mar 5. [Epub ahead of print]
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An Adaptive Genetic Algorithm for Selection of Blood-Based Biomarkers for Prediction of Alzheimer's Disease Progression (2015) Vandewater L, Brusic V, Wilson W, Macaulay L, Zhang P BMC Bioinformatics
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The Tyrosine Kinase Inhibitors Imatinib and Dasatinib Reduce Myeloid Suppressor Cells and Release Effector Lymphocyte Responses. (2015) Christiansson L, Soderlund S, Mangsbo SM, Hjorth-Hansen H, Höglund M, Markevarn B, Richter J, Stenke L, Mustjoki S, Loskog A, Olsson-Stromberg U. Mol Cancer Ther. 2015 Mar 11. pii: molcanther.0849.2014. [Epub ahead of print]
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Identifying amyloid pathology–related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study (2015) Leung YY, Toledo JB, Nefedov A, Polikar R, Raghavan N, Xie SX, Farnum M, Schultz T, Baek Y, Deerlin VV, Hu WT, Holtzman DM, Fagan AM, Perrin RJ, Grossman M, Soares HD, Kling MA, Mailman M, Arnold SE, Narayan VA, Lee VMY, Shaw LM, Baker D, Wittenberg GM, Trojanowski JQ, Wang LS Alzheimer's & Dementia
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Phase I Trial of the Pan-Pi3k Inhibitor Pilaralisib (Sar245408/Xl147) in Patients with Chronic Lymphocytic Leukemia (Cll) or Relapsed/Refractory Lymphoma (2015) Brown JR, Davids MS, Rodon J, Abrisqueta P, Kasar SN, Lager J, Jiang J, Egile C, Awan FT American Association for Cancer Research
Interpreting the multi-biomarker disease activity score in the context of tocilizumab treatment for patients with rheumatoid arthritis (2015) Reiss WG, Devenport JN, Low JM, Wu G, Sasso E Rheumatol Int
Lack of an association of BDNF Val66Met polymorphism and plasma BDNF with hippocampal volume and memory. (2015) Kim A, Fagan AM, Goate AM, Benzinger TL, Morris JC, Head D; Alzheimer’s Disease Neuroimaging Initiative. Cogn Affect Behav Neurosci. 2015 Mar 18. [Epub ahead of print]
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Detection of Rheumatoid Arthritis-Interstitial Lung Disease is Enhanced by Serum Biomarkers. (2015) Doyle TJ, Patel AS, Hatabu H, Nishino M, Wu G, Osorio JC, Golzarri MF, Traslosheros A, Chu SG, Frits ML, Iannaccone CK, Koontz D, Fuhrman C, Weinblatt ME, El-Chemaly SY, Washko GR, Hunninghake GM, Choi AM, Dellaripa PF, Oddis CV, Shadick NA, Ascherman DP, Rosas IO. Am J Respir Crit Care Med. 2015 Mar 30. [Epub ahead of print]
Late Stage Cancer Patients Remain Highly Responsive to Immune Activation by the Selective TLR8 Agonist Motolimod (VTX-2337) (2015) Dietsch GN, Randall TD, Gottardo R, Northfelt DW, Ramanathan RK, Cohen PA, Manjarrez KL, Newkirk M, Bryan JK, Hershberg RM Clinical Cancer Research
Identification of an age-dependent biomarker signature in children and adolescents with autism spectrum disorders (2015) Ramsey JM, Guest PC, Broek JA, Glennon JC, Rommelse N, Franke B, Rahmoune H, Buitelaar JK, Bahn S. Mol Autism
Dysregulation of Serum Gamma Interferon Levels in Vascular Chronic Q Fever Patients Provides Insights into Disease Pathogenesis (2015) Pennings JLA, Kremers MNT, Hodemaekers HM, Hagenaars JCJP, Koning OHJ, Renders NHM, Hermans MHA, De Klerk A, Notermans DW, Wever PC, Janssen R Clinical and Vaccine Immunology
The long-acting ß2-agonist olodaterol attenuates pulmonary inflammation. (2015) Wex E, Kollak I, Duechs MJ, Naline E, Wollin L, Devillier P. Br J Pharmacol. 2015 Mar 30. doi: 10.1111/bph.13143. [Epub ahead of print]
A phase 2 randomized dose-ranging study of the JAK2-selective inhibitor fedratinib (SAR302503) in patients with myelofibrosis (2015) Pardanani A, Tefferi A, Jamieson C, Gabrail NY, Lebedinsky C, Gao G, Liu F, Xu C, Cao H and Talpaz M Blood Cancer Journal
Novel first-dose adverse drug reactions during a phase I trial of olipudase alfa (recombinant human acid sphingomyelinase) in adults with Niemann-Pick disease type B (acid sphingomyelinase deficiency). (2015) McGovern MM, Wasserstein MP, Kirmse B, Duvall WL, Schiano T, Thurberg BL, Richards S, Cox GF. Genet Med. 2015 Apr 2. doi: 10.1038/gim.2015.24. [Epub ahead of print]
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Integrative proteomic analysis of the NMDA NR1 knockdown mouse model reveals effects on central and peripheral pathways associated with schizophrenia and autism spectrum disorders. (2015) Wesseling H, Guest PC, Lee CM, Wong EH, Rahmoune H, Bahn S Mol Autism.
A 7-month cigarette smoke inhalation study in C57BL/6 mice demonstrates reduced lung inflammation and emphysema following smoking cessation or aerosol exposure from a prototypic modified risk tobacco product. (2015) Phillips B, Veljkovic E, Peck MJ, Buettner A, Elamin A, Guedj E, Vuillaume G, Ivanov NV, Martin F, Bouéb S, Schlage WK, Schneider T, Titz B, Talikka M, Vanscheeuwijck P, Hoeng J, Peitsch MC. Food Chem Toxicol. 2015 Apr 2. pii: S0278-6915(15)00088-5. doi: 10.1016/j.fct.2015.03.009. [Epub ahead of print]
Identification of plasma biomarker concentration changes resulting from the administration of the Vascular Disrupting Agent BNC105 across 3 clinical trials in mesothelioma, ovarian and renal cancer (2015) Kremmidiotis G, Leske A, Simpson J, Doolin E, Iglesias J AACR 2015
Systems Biology Reveals Cigarette Smoke-Induced Concentration-Dependent Direct and Indirect Mechanisms That Promote Monocyte-Endothelial Cell Adhesion. (2015) Poussin C, Laurent A, Peitsch MC, Hoeng J, De Leon H Toxicol Sci.
Cd4+ T-Cell Profiles and Peripheral Blood Ex-Vivo Responses to T-Cell Directed Stimulation Delineate Copd Phenotypes (2015) Roberts MEPH, Brandon W.; Brohawn, Philip; Pilataxi, Fernanda; Guo, Xiang; Kuziora, Michael; Bowler, Russell P.; White, Wendy I. Chronic Obstructive Pulmonary Diseases
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MEDI-551 Treatment Effectively Depletes B Cells and Reduces Serum Titers of Autoantibodies in Sle1-Human CD19 Transgenic Mice. (2015) Gallagher S, Yusuf I, McCaughtry TM, Turman S, Sun H, Kolbeck R, Herbst R, Wang Y Arthritis Rheumatol.
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Novel data-mining approach identifies biomarkers for diagnosis of Kawasaki disease (2015) Tremoulet AH, Dutkowski J, Sato Y, Kanegaye JT, Ling XB, Burns JC Pediatr Res.
Leptin, BMI, and a Metabolic Gene Expression Signature Associated with Clinical Outcome to VEGF Inhibition in Colorectal Cancer (2015) Pommier AJC, Farren M, Patel B, Wappett M, Michopoulos F, Smith NR, Kendrew J, Frith J, Huby R, Eberlein C, Campbell H, Womack C, Smith PD, Robertson J, Morgan S, Critchlow SE, Barry ST Cell Metabolism
Mechanism-based combination treatment dramatically increases therapeutic efficacy in murine globoid cell leukodystrophy. (2015) Hawkins-Salsbury JA, Shea L, Jiang X, Hunter DA, Guzman AM, Reddy AS, Qin EY, Li Y, Gray SJ, Ory DS, Sands MS. J Neurosci. 2015 Apr 22;35(16):6495-505. doi: 10.1523/JNEUROSCI.4199-14.2015.
Common Effects on Cancer Cells Exerted by a Random Positioning Machine and a 2D Clinostat (2015) Svejgaard B, Wehland M, Ma X, Kopp S, Sahana J, Warnke E, Aleshcheva G, Hemmersbach R, Hauslage J, Grosse J, Bauer J, Corydon TJ, Islam T, Infanger M, Grimm D PLoS One
Characterization of Renal Biomarkers for Use in Clinical Trials: Effect of Preanalytical Processing and Qualification Using Samples from Subjects with Diabetes (2015) Brott DA, Furlong ST, Adler SH, Hainer JW, Arani RB, Pinches M, Rossing P, Chaturvedi N Drug Design, Development and Therapy
Alarmin function of galectin-9 in murine respiratory tularemia. (2015) Steichen AL, Simonson TJ, Salmon SL, Metzger DW, Mishra BB, Sharma J. PLoS One. 2015 Apr 21;10(4):e0123573. doi: 10.1371/journal.pone.0123573. eCollection 2015.
Central and peripheral changes underlying susceptibility and resistance to social defeat stress – a proteomic profiling study (2015) Stelzhammer V, Ozcan S, Gottschalk MG, Steeb H, Hodes GE, Guest PC, Rahmoune H, Wong EHF, Russo SJ, Bahn S Diagnostics in Neuropsychiatry
Systems toxicology-based assessment of the candidate modified risk tobacco product THS2.2 for the adhesion of monocytic cells to human coronary arterial endothelial cells (2015) Poussin C, Laurent A, Peitsch MC, Hoeng J, and De Leon H Toxicology
The Effect Trial: Evaluating Exacerbations, Biomarkers, and Safety Outcomes with Two Dose Levels of Fluticasone Propionate/Formoterol in Copd (2015) Papi A, Jones PW, Dalvi PS, Mcaulay K, Mciver T, Dissanayake S International Journal of COPD
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2014
Cytokine alterations in first-episode schizophrenia patients before and after antipsychotic treatment (2014) de Witte L, Tomasik J, Schwarz E, Guest PC, Rahmoune H, Kahn RS, Bahn S Schizophr Res. 2014 Feb 26. pii: S0920-9964(14)00071-1
Inflammatory Molecular Signature Associated With Infectious Agents in Psychosis (2014) Hayes LN, Severance EG, Leek JT, Gressitt KL, Rohleder C, Coughlin JM, Leweke FM, Yolken RH, Sawa A Schizophr Bull. 2014 Apr 17. [Epub ahead of print]
Circulating chemokines in relation to coronary plaque characteristics on radiofrequency intravascular ultrasound and cardiovascular outcome. (2014) Cheng JM, Oemrawsingh RM, Akkerhuis KM, Garcia-Garcia HM, de Boer SP, Battes LC, Buljubasic N, Lenzen MJ, de Jaegere PP, van Geuns RJ, Serruys PW, Kardys I, Boersma E. Informa Healthcare Biomarkers 2014 Sep 8:1-9. [Epub ahead of print]
Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction. (2014) Bär C, de Jesus BB, Serrano R, Tejera A, Ayuso E, Jimenez V, Formentini I, Bobadilla M, Mizrahi J, de Martino A, Gomez G, Pisano D, Mulero F, Wollert KC, Bosch F, Blasco MA. Nat Commun. 2014 Dec 18;5:5863. doi: 10.1038/ncomms6863.
Molecular Neuropsychology: Creation of Test-Specific Blood Biomarker Algorithms (2014) O'Bryant SE, Xiao G, Barber R, Cullum CM, Weiner M, Hall J, Edwards M, Grammas P, Wilhelmsen K, Doody R, Diaz-Arrastia R Dementia and Geriatric Cognitive Disorders
Effect of ozone exposure and infection on bronchoalveolar lavage: Sex differences in response patterns (2014) Mikerov AN, Phelps DS, Gan X, Umstead TM, Haque R, Wang G, Floros J Toxicol Lett. 2014 Apr 21. pii: S0378-4274(14)00167-2
Fat Quality and Incident Cardiovascular Disease, All-Cause Mortality and Cancer Mortality (2014) Rosenquist KJ, Massaro JM, Pedley A, Long MT, Kreger BE, Vasan RS, Murabito JM, Hoffmann U, Fox CS. Journal of Clinical Endocrinology & Metabolism 2014 Sep 16:jc20134296. [Epub ahead of print]
Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-ß receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced cancer. (2014) Rodón J, Carducci M, Sepulveda-Sánchez JM, Azaro A, Calvo E, Seoane J, Braña I, Sicart E, Gueorguieva I, Cleverly A, Pillay NS, Desaiah D, Estrem ST, Paz-Ares L, Holdhoff M, Blakeley J, Lahn MM, Baselga J. Invest New Drugs. 2014 Dec 23. [Epub ahead of print]
A phase I study of the human monoclonal anti-NRP1 antibody MNRP1685A in patients with advanced solid tumors (2014) Weekes CD, Beeram M, Tolcher AW, Papadopoulos KP, Gore L, Hegde P, Xin Y, Yu R, Shih LM, Xiang H, Brachmann RK, Patnaik A Invest New Drugs. 2014 Mar 7. [Epub ahead of print]
Aliskiren and valsartan mediate left ventricular remodeling post-myocardial infarction in mice through MMP-9 effects (2014) Ramirez TA, Iyer RP, Ghasemi O, Lopez EF, Levin DB, Zhang J, Zamilpa R, Chou YM, Jin YF, Lindsey ML J Mol Cell Cardiol. 2014 Apr 22. pii: S0022-2828(14)00118-7
Cerium oxide nanoparticles attenuate monocrotaline induced right ventricular hypertrophy following pulmonary arterial hypertension (2014) Kolli MB, Manne ND, Para R, Nalabotu SK, Nandyala G, Shokuhfar T, He K, Hamlekhan A, Ma JY, Wehner PS, Dornon L, Arvapalli R, Rice KM, Blough ER. Biomaterials. 2014 Sep 12. pii: S0142-9612(14)00962-4. doi: 10.1016/j.biomaterials.2014.08.037. [Epub ahead of print]
High fidelity between saliva proteomics and the salivary glands' biological state defines biomarker-signatures for primary Sjögren's syndrome. (2014) Delaleu N, Mydel P, Kwee I, Brun JG, Jonsson MV, Jonsson R. Arthritis Rheumatol. 2014 Dec 29. doi: 10.1002/art.39015. [Epub ahead of print]
Apolipoprotein H Expression Is Associated with Il28b Genotype and Viral Clearance in Hepatitis C Virus Infection (2014) Laird ME, Mohsen A, Duffy D, Mamdouh R, Lefouler L, Casrouge A, El-Daly M, Rafik M, Abdel-Hamid M, Soulier A, Pawlotsky J-M, Hézode C, Rosa I, Renard P, Mohamed MK, Bonnard P, Izopet J, Mallet V, Pol S, Albert ML, Fontanet A Journal of Hepatology
Multiplex Screen of Serum Biomarkers in (2014) Statlanda J, Donlin-Smithb CM, Tapscottc SJ, van der Maarel S, Tawil, R Journal of Neuromuscular Diseases DOI 0.3233/JND-140034
CXCR4 promotes renal tubular cell survival in male diabetic rats: implications for ligand inactivation in the human kidney. (2014) Siddiqi FS, Chen L, Advani SL, Thai K, Batchu SN, Alghamdi TA, White KE, Sood MM, Gibson IW, Connelly KA, Marsden PA, Advani A. Endocrinology. 2014 Dec 30:en20141650. [Epub ahead of print]
Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study (2014) O'Neal WK, Anderson W, Basta PV, Carretta EE, Doerschuk CM, Barr RG, Bleecker ER, Christenson SA, Curtis JL, Han MK, Hansel NN, Kanner RE, Kleerup EC, Martinez FJ, Miller BE, Peters SP, Rennard SI, Scholand MB, Tal-Singer R, Woodruff PG, Couper DJ, Davis SM J Transl Med. 2014 Jan 8;12(1):9
Plasma S100A12 is associated with functional outcome after ischemic stroke: Research for Biomarkers in Ischemic Stroke (2014) Wakisakaa Y, Agoa T, Kamouchib M, Kurodaa J, Matsuoa R, Hataa J, Gotoha S, Isomurad T, Awanod H, Suzukid, K, Fukudaa K, Okadaf Y, Kiyoharac Y, Ooboshig H, Kitazonoa T, on behalf of the REBIOS Investigators Journal of the Neurological Sciences 04 Mar 2014
A phase I dose-escalation study to a predefined dose of a transforming growth factor-ß1 monoclonal antibody (TßM1) in patients with metastatic cancer (2014) Cohn A, Lahn MM, Williams KE, Cleverly AL, Pitou C, Kadam SK, Farmen MW, Desaiah D, Raju R, Conkling P, Richards D International Journal of Oncology 10.3892/ijo.2014.2679
Targeting glycosaminoglycans in the lung by an engineered CXCL8 as a novel therapeutic approach to lung inflammation (2014) Adage T, Konya V, Weber C, Strutzmann E, Fuchs T, Zankl C, Gerlza T, Jeremic D, Heinemann A, Kungl AJ. Eur J Pharmacol. 2014 Dec 29. pii: S0014-2999(14)00889-9. doi: 10.1016/j.ejphar.2014.12.019. [Epub ahead of print]
Significance of plasma adiponectin for diagnosis, neurological severity and functional outcome in ischemic stroke - Research for Biomarkers in Ischemic Stroke (REBIOS) (2014) Matsuo R, Ago T, Kamouchi M, Kuroda J, Kuwashiro T, Hata J, Sugimori H, Fukuda K, Gotoh S, Makihara N, Fukuhara M, Awano H, Isomura T, Suzuki K, Yasaka M, Okada Y, Kiyohara Y, Kitazono T BMC Neurol. 2013 Apr 8;13:32
An Anti-Neuroinflammatory That Targets Dysregulated Glia Enhances the Efficacy of CNS-Directed Gene Therapy in Murine Infantile Neuronal Ceroid Lipofuscinosis. (2014) Macauley SL, Wong AMS, Shyng C, Augner DP, Dearborn JT, Pearse Y, Roberts MS, Fowler SC, Cooper JD, Watterson DM, Sands MS Journal of Neuroscience 2014 Sep 24;34(39):13077-82. doi: 10.1523/JNEUROSCI.2518-14.2014.
Basal inflammation and innate immune response in chronic multisite musculoskeletal pain. (2014) Generaal E, Vogelzangs N, Macfarlane GJ, Geenen R, Smit JH, Dekker J, Penninx BW. Pain. 2014 Aug;155(8):1605-12. doi: 10.1016/j.pain.2014.05.007. Epub 2014 May 9.
Discovery of Emphysema Relevant Molecular Networks from an A/J Mouse Inhalation Study Using Reverse Engineering and Forward Simulation (REFS™) (2014) Xiang Y, Kogel U, Gebel S, Peck MJ, Peitsch MC, Akmaev VR, Hoeng J Gene Regul Syst Bio. 2014 Feb 19;8:45-61
A Phase 1 Dose-Finding Study of the Novel Toll-like Receptor 8 Agonist VTX 2337 in Adult Subjects with Advanced Solid Tumors or Lymphoma (2014) Northfelt DW, Ramanathan RK, Cohen PA, Von Hoff DD, Weiss GJ, Dietsch GN, Manjarrez KL, Randall TD, Hershberg RM Clin Cancer Res. 2014 May 7
Efficacy, safety, pharmacokinetics and pharmacodynamics of SAR245409 (XL765), an orally administered PI3K/mTOR inhibitor: a phase 1 expansion cohort in patients with relapsed or refractory lymphoma. (2014) Papadopoulos KP, Egile C, Ruiz-Soto R, Jiang J, Shi W, Bentzien F, Rasco D, Abrisqueta P, Vose JM, Tabernero J. Informa Healthcare Leuk Lymphoma. 2014 Oct 10:1-32. [Epub ahead of print]
The role of endogenous epidermal growth factor receptor ligands in mediating corneal epithelial homeostasis. (2014) Peterson JL, Phelps ED, Doll MA, Schaal S, Ceresa BP. Invest Ophthalmol Vis Sci. 2014 May 1;55(5):2870-80. doi: 10.1167/iovs.13-12943.
Synovial explant inflammatory mediator production corresponds to rheumatoid arthritis imaging hallmarks: a cross sectional study (2014) Andersen, M., Boesen, M., Ellegaard, K., Christensen, R., Söderström, K., Søe, N., & Bliddal, H Arthritis Research & Therapy, 16(3), R107
Proteomic changes in serum of first onset, antidepressant drug-naïve major depression patients. (2014) Stelzhammer V, Haenisch F, Chan MK, Cooper JD, Steiner J, Steeb H, Martins-de-Souza D, Rahmoune H, Guest PC, Bahn S. Int J Neuropsychopharmacol. 2014 Oct;17(10):1599-608. doi: 10.1017/S1461145714000819. Epub 2014 Jun 5.
CSF Apo-E levels associate with cognitive decline and MRI changes (2014) Toledo JB, Da X, Weiner MW, Wolk DA, Xie SX, Arnold SE, Davatzikos C, Shaw LM, Trojanowski JQ; For the Alzheimer’s Disease Neuroimaging Initiative Acta Neuropathol. 2014 Jan 3. [Epub ahead of print]
Reduction of pro-inflammatory cytokines in rats following 7-day oral supplementation with a proprietary eggshell membrane-derived product (2014) Ruff KJ, DeVore DP Modern Research in Inflammation, 3, 19-25
Spheroid formation of human thyroid cancer cells (2014) Warnke E, Pietsch J, Wehland M, Bauer J, Infanger M, Görög M, Hemmersbach R, Braun M, Ma X, Sahana J, Grimm D Cell Communication and Signaling 2014, 12:32
The association of plasma biomarkers with computed tomography-assessed emphysema phenotypes (2014) Carolan BJ, Hughes G, Morrow J, Hersh CP, O'Neal WK, Rennard S, Pillai SG, Belloni P, Cockayne DA, Comellas AP, Han M, Zemans RL, Kechris K, Bowler RP. Respiratory Research 2014 Oct 12;15(1):127. doi: 10.1186/s12931-014-0127-9.
Effects of Ruxolitinib Treatment on Metabolic and Nutritional Parameters in Patients With Myelofibrosis From COMFORT-I. (2014) Mesa RA, Verstovsek S, Gupta V, Mascarenhas J, Atallah E, Burn T, Sun W, Sandor V, Gotlib J. Clin Lymphoma Myeloma Leuk [Epub ahead of print]
Regional Neurovascular Inflammation and Apoptosis Are Detected after Electrical Contact Injury (2014) Prindeze NJ, Jo DY, Paul DW, Ortiz RT, Carney BC, Bullock RM, Moffatt LT, Shupp JW Journal of Burn Care & Research
Nonclinical Safety Profile of BMS-986001, a Nucleoside Transcriptase Inhibitor for Combination Retroviral Therapy (2014) Mausumee G, Frank S, Shawn C, Dara H, Zhao Y, Soleil PM, Sanderson TP, Michael G, Marc D Int J Toxicol. 2014 May 20;33(3):204-218
Predicting therapeutic efficacy of intravenous immunoglobulin (IVIG) in individual patients with relapsing remitting multiple sclerosis (RRMS) by functional genomics (2014) Berger T, Jacob C, Haas J, Ransmayr G, Guger M, Zettl UK, Di Pauli F, Taumberger B, Wietek S, Meuer S, Reindl M, Giese T Journal of Neuroimmunology DOI: 10.1016/j.jneuroim.2014.10.001
Cardiac aging is initiated by matrix metalloproteinase-9-mediated endothelial dysfunction. (2014) Yabluchanskiy A, Ma Y, Chiao YA, Lopez EF, Voorhees AP, Toba H, Hall ME, Han HC, Lindsey ML, Jin YF. Am J Physiol Heart Circ Physiol. 2014 May 15;306(10):H1398-407. doi: 10.1152/ajpheart.00090.2014. Epub 2014 Mar 21.
Development, manufacturing and characterization of a highly purified, liquid immunoglobulin g preparation from human plasma. (2014) Laursen IA, Blou L, Sullivan JS, Bang P, Balstrup F, Houen G. Transfus Med Hemother. 2014 Jun;41(3):205-12. doi: 10.1159/000357982. Epub 2014 Apr 14.
Significance of Plasma Adiponectin for Diagnosis, Neurological Severity and Functional Outcome in Ischemic Stroke — Research for Biomarkers in Ischemic Stroke (Rebios) (2014) Kuwashiro T, Ago T, Kamouchi M, Matsuo R, Hata J, Kuroda J, Fukuda K, Sugimori H, Fukuhara M, Awano H, Isomura T, Suzuki K, Yasaka M, Okada Y, Kiyohara Y, Kitazono T Metabolism
The application of multiple reaction monitoring and multi-analyte profiling to HDL proteins (2014) Yassine HN, Jackson AM, Borges CR, Billheimer D, Koh H, Smith D, Reaven P, Lau SS, Borchers CH Lipids Health Dis. 2014 Jan 8;13(1):8
The Impact of APOE Status on Relationship of Biomarkers of Vascular Risk and Systemic Inflammation to Neuropsychiatric Symptoms in Alzheimer's Disease (2014) Hall JR, Wiechmann AR, Johnson LA, Edwards M, Barber RC, Cunningham R, Singh M, O'Bryant SE J Alzheimers Dis. 2014 Feb 20. [Epub ahead of print]
A prospective assessment of the effect of aminophylline therapy on urine output and inflammation in critically ill children (2014) Tamburro RF, Thomas NJ, Ceneviva GD, Dettorre MD, Brummel GL, Lucking SE Front. Pediatr. 2:59
Towards a Psychosis Risk Blood Diagnostic for Persons Experiencing High-Risk Symptoms: Preliminary Results From the NAPLS Project. (2014) Perkins DO, Jeffries CD, Addington J, Bearden CE, Cadenhead KS, Cannon TD, Cornblatt BA, Mathalon DH, McGlashan TH, Seidman LJ, Tsuang MT, Walker EF, Woods SW, Heinssen R. Schizophr Bull. 2014 Aug 6. pii: sbu099. [Epub ahead of print]
A Phase 2, Randomized, Double-blind, Multicenter Study Comparing Siltuximab Plus Best Supportive Care With Placebo Plus Best Supportive Care in Anemic Patients With International Prognostic Scoring System Low- or Intermediate-1–Risk Myelodysplastic Syndrome (2014) Garcia-Manero G, Gartenberg G, Steensma DP, Schipperus MR, Breems DA, de Paz R, Valcárcel D, Kranenburg B, Reddy M, Komrokji RS Am J Hematol. 2014 May 31
Plasma biosignature and brain pathology related to persistent cognitive impairment in late-life depression. (2014) Diniz BS, Sibille E, Ding Y, Tseng G, Aizenstein HJ, Lotrich F, Becker JT, Lopez OL, Lotze MT, Klunk WE, Reynolds CF, Butters MA. Mol Psychiatry. 2014 Aug 5. doi: 10.1038/mp.2014.76. [Epub ahead of print]
Pharmacologic inhibition of S-nitrosoglutathione reductase protects against experimental asthma in BALB/c mice through attenuation of both bronchoconstriction and inflammation (2014) Blonder JP, Mutka SC, Sun X, Qiu J, Green LH, Mehra NK, Boyanapalli R, Suniga M, Look K, Delany C, Richards JP, Looker D, Scoggin C, Rosenthal GJ BMC Pulm Med. 2014 Jan 10;14(1):3
MRI signal and texture features for the prediction of MCI to Alzheimer's disease progression (2014) Martínez -Torteya A, Rodríguez-Rojas J, Celaya-Padilla JM, Galván-Tejada JI, Treviño V, Tamez-Peña JG Proc. SPIE 9035
Altered microglial response to Aß plaques in APPPS1-21 mice heterozygous for TREM2 (2014) Ulrich JD, Finn MB, Wang Y, Shen A, Mahan TE, Jiang H, Stewart FR, Piccio L, Colonna M, Holtzman DM Mol Neurodegener. 2014 Jun 3;9(1):20
Oxidative stress and reduced responsiveness of challenged circulating leukocytes following pulmonary instillation of metal-rich particulate matter in rats. (2014) Erdely A, Antonini JM, Young SH, Kashon ML, Gu JK, Hulderman T, Salmen R, Meighan T, Roberts JR, Zeidler-Erdely PC. Part Fibre Toxicol. 2014 Aug 15;11:34. doi: 10.1186/s12989-014-0034-8.
Exploring effects of a natural combination medicine on exercise-induced inflammatory immune response: A double-blind RCT (2014) Pilat C, Frech T, Wagner A, Krüger K, Hillebrecht A, Pons-Kühnemann J, Scheibelhut C, Bödeker RH, Mooren FC Scand J Med Sci Sports. 2014 Jun 12
Genome-Wide Association Study of CSF Levels of 59 Alzheimer's Disease Candidate Proteins: Significant Associations with Proteins Involved in Amyloid Processing and Inflammation (2014) Kauwe JS, Bailey MH, Ridge PG, Perry R, Wadsworth ME, Hoyt KL, Staley LA, Karch CM, Harari O, Cruchaga C, Ainscough BJ, Bales K, Pickering EH, Bertelsen S; Alzheimer's Disease Neuroimaging Initiative, Fagan AM, Holtzman DM, Morris JC, Goate AM PLoS Genet
The Use of Multiplex Platforms for Absolute and Relative Protein Quantification of Clinical Material (2014) Christiansson L, Mustjoki S, Simonsson B, Olsson-Strömberg U, Loskog ASI, Mangsbo SM EuPA Open Proteomics
Implementing lessons learned from previous bronchial biopsy trials in a new randomized controlled COPD biopsy trial with roflumilast (2014) Barnes NC, Saetta M, Rabe KF BMC Pulm Med. 2014 Jan 31;14(1):9
Carlumab, an anti-C-C chemokine ligand 2 monoclonal antibody, in combination with four chemotherapy regimens for the treatment of patients with solid tumors: an open-label, multicenter phase 1b study (2014) Brana I, Calles A, LoRusso PM, Yee LK, Puchalski TA, Seetharam S, Zhong B, de Boer CJ, Tabernero J, Calvo E Target Oncol. 2014 Jun 15
Bone marrow from blotchy mice is nonessential to regulate blood copper and aortic pathologies in LDLR deficient mice during chronic angiotensin II infusion (2014) Harris D, Liang Y, Chen C, Li S, Patel O, Qin Z Annals of Vascular Surgery
Candidate Blood Proteome Markers of Alzheimer's Disease Onset and Progression: A Systematic Review and Replication Study (2014) Kiddle SJ, Sattlecker M, Proitsi P, Simmons A, Westman E, Bazenet C, Nelson SK, Williams S, Hodges A, Johnston C, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Newhouse S, Lovestone S, Dobson RJ Journal of Alzheimer's Disease
Effects of an Anti-Tslp Antibody on Allergen-Induced Asthmatic Responses (2014) Gauvreau GM, O'byrne PM, Boulet L-P, Wang Y, Cockcroft D, Bigler J, Fitzgerald JM, Boedigheimer M, Davis BE, Dias C, Gorski KS, Smith L, Bautista E, Comeau MR, Leigh R, Parnes JR New England Journal of Medicine
Low levels of cerebrospinal fluid complement 3 and factor H predict faster cognitive decline in mild cognitive impairment (2014) Toledo JB, Korff A, Shaw LM, Trojanowski JQ, Zhang J Alzheimer's Research & Therapy 2014, 6:36
TRAMP Prostate Tumor Growth Is Slowed by Walnut Diets Through Altered IGF-1 Levels, Energy Pathways, and Cholesterol Metabolism (2014) Kim H, Yokoyama W, Davis PA. J Med Food. 2014 Oct 29. [Epub ahead of print]
Clinical and Preclinical Characterization of the Histamine H4 Receptor Antagonist Jnj-39758979 (2014) Thurmond RL, Chen B, Dunford PJ, Greenspan AJ, Karlsson L, La D, Ward P, Xu XL Journal of Pharmacology and Experimental Therapeutics
Serum proteomic analysis identifies sex-specific differences in lipid metabolism and inflammation profiles in adults diagnosed with Asperger syndrome (2014) Steeb H, Ramsey JM, Guest PC, Stocki P, Cooper JD, Rahmoune H, Ingudomnukul E, Auyeung B, Ruta L, Baron-Cohen S, Bahn S Mol Autism. 2014 Jan 27;5(1):4
Functional Analysis via Standardized Whole-Blood Stimulation Systems Defines the Boundaries of a Healthy Immune Response to Complex Stimuli (2014) Duffy D, Rouilly V, Libri V, Hasan M, Beitz B, David M, Urrutia A, Bisiaux A, LaBrie ST, Dubois A, Boneca IG, Delval C, Thomas S, Rogge L, Schmolz M, Quintana-Murci L, Albert ML Immunity Volume 40, Issue 3, 20 March 2014, Pages 436–450
CD47 Blockade Reduces Ischemia-Reperfusion Injury and Improves Outcomes in a Rat Kidney Transplant Model (2014) Lin Y, Manning PT, Jia J, Gaut JP, Xiao Z, Capoccia BJ, Chen CC, Hiebsch RR, Upadhya G, Mohanakumar T, Frazier WA, Chapman WC Transplantation. 2014 Jun 30. [Epub ahead of print]
Plasma leptin levels are not predictive of dementia in patients with mild cognitive impairment. (2014) Oania R, McEvoy LK. Age Ageing. 2014 Oct 27. pii: afu160. [Epub ahead of print]
The Application of Multiple Reaction Monitoring to Assess Apoa-I Methionine Oxidations in Diabetes and Cardiovascular Disease (2014) Yassine HN, Jackson AM, Reaven PD, Nedelkov D, Nelson RW, Lau SS, Borchers CH Translational Proteomics
Vectra DA for the objective measurement of disease activity in patients with rheumatoid arthritis. (2014) Segurado OG, Sasso EH. Clin Exp Rheumatol.
Total Cholesterol and Neuropsychiatric Symptoms in Alzheimer's Disease: The Impact of Total Cholesterol Level and Gender (2014) Hall JR, Wiechmann AR, Johnson LA, Edwards M, Barber RC, Cunningham R, Singh M, O'Bryant SE Dementia and Geriatric Cognitive Disorders Vol. 38, No. 5-6, 2014
Lower leptin/adiponectin ratio and risk of rapid lung function decline in chronic obstructive pulmonary disease. (2014) Suzuki M, Makita H, Ostling J, Thomsen LH, Konno S, Nagai K, Shimizu K, Pedersen JH, Ashraf H, Bruijnzeel PL, Maciewicz RA, Nishimura M; for the Hokkaido COPD cohort study and DLCST investigators. Ann Am Thorac Soc. 2014 Nov 5. [Epub ahead of print]
Immunomodulatory Activities of a Concentrated Fruit and Vegetable Juice Tested in a Randomized, Placebo-Controlled, Double-Blind Clinical Trial in Healthy Volunteers (2014) Schmolz M, März RW, Schaudt M, Schaudt C, Lauster C Food and Nutrition Sciences, Vol. 5 No. 4, 2014, pp. 341-350
Normal Ranges and Variability of Novel Urinary Renal Biomarkers in Sprague-Dawley Rats (2014) Gautier JC, Gury T, Guffroy M, Khan-Malek R, Hoffman D, Pettit S, Harpur E Toxicol Pathol. 2014 Apr 7. [Epub ahead of print]
Combination treatment with oncolytic Vaccinia virus and cyclophosphamide results in synergistic antitumor effects in human lung adenocarcinoma bearing mice (2014) Hofmann E, Weibel S, Szalay AA Journal of Translational Medicine 2014 Jul 17;12:197. doi: 10.1186/1479-5876-12-197
Circulating acute phase proteins in relation to extent and composition of coronary atherosclerosis and cardiovascular outcome: results from the ATHEROREMO-IVUS study (2014) Battes LC, Akkerhuis KM, Cheng JM, Garcia-Garcia HM, Oemrawsingh RM, de Boer SPM, Reger E, van Geuns R-J, Serruys PW, Boersma E, Kardys I International Journal of Cardiology
Vitamin D Binding Protein as a Serum Biomarker of Alzheimer's Disease. (2014) Bishnoi RJ, Palmer RF, Royall DR. Journal of Alzheimer's Disease 2014 Jul 30. [Epub ahead of print]
A targeted multiplexed proteomic investigation identifies ketamine-induced changes in immune markers in rat serum and expression changes in protein kinases/phosphatases in rat brain. (2014) Wesseling H, Rahmoune H, Tricklebank M, Guest PC, Bahn S. J Proteome Res. 2014 Nov 2. [Epub ahead of print]
Altered Macrophage-Phenotype Transition Impairs Skeletal Muscle Regeneration (2014) Wang H, Melton D, Porter L, Sarwar ZU, McManus LM, Shireman PK Am J Pathol. 2014 Feb 10. pii: S0002-9440(14)00025-X
Truncated CXCL10 is associated with failure to achieve spontaneous clearance of acute hepatitis C infection (2014) Riva A, Laird M, Casrouge A, Ambrozaitis A, Williams R, Naoumov NV, Albert ML, Chokshi S Hepatology. 2014 Mar 26
Plasma protein biomarkers enhance the clinical prediction of kidney injury recovery in patients undergoing liver transplantation. (2014) Levitsky J, Baker TB, Jie C, Ahya S, Levin M, Friedewald J, Al-Saden P, Salomon DR, Abecassis MM. Hepatology 2014 Jul 31. doi: 10.1002/hep.27346. [Epub ahead of print]
Multiplexed protein profiling after aneurysmal subarachnoid hemorrhage: Characterization of differential expression patterns in cerebral vasospasm. (2014) Walcott BP, Patel AP, Stapleton CJ, Trivedi RA, Young AM, Ogilvy CS. J Clin Neurosci. 2014 Jul 28. pii: S0967-5868(14)00318-X. doi: 10.1016/j.jocn.2014.06.004. [Epub ahead of print]
Brown Norway Chromosome 1 Congenic Reduces Symptoms of Renal Disease in Fatty Zucker Rats (2014) Warden CH, Slupsky C, Griffey SM, Bettaieb A, Min E, Le A, Fisler JS, Hansen S, Haj F, Stern JS PLoS ONE
Ethnicity Moderates Dementia's Biomarkers. (2014) Royall DR, Palmer RF Journal of Alzheimer's Disease 2014 Jul 30. [Epub ahead of print]
FASTKD2 is associated with memory and hippocampal structure in older adults. (2014) Ramanan VK, Nho K, Shen L, Risacher SL, Kim S, McDonald BC, Farlow MR, Foroud TM, Gao S, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Aisen PS, Petersen RC, Jack CR Jr, Shaw LM, Trojanowski JQ, Weiner MW, Green RC, Toga AW, De Jager PL, Yu L, Bennett DA, Saykin AJ. Mol Psychiatry. 2014 Nov 11. doi: 10.1038/mp.2014.142. [Epub ahead of print]
Distinctive Colonic Mucosal Cytokine Signature in New-Onset, Untreated Pediatric Crohn Disease (2014) Sylvester FA, Draghi A, Menoret A, Fernandez ML, Wang Z, Vella AT Journal of Pediatric Gastroenterology and Nutrition
Oxidative Stress, Testosterone, and Cognition among Caucasian and Mexican-American Men with and without Alzheimer's Disease (2014) Cunningham RL1, Singh M1, O'Bryant SE2, Hall JR3, Barber RC J Alzheimers Dis. 2014 Feb 4. [Epub ahead of print]
Rapid Onset Clinical and Mechanistic Effects of anti-C5aR Treatment in the Mouse Collagen Induced Arthritis Model (2014) Andersson C, Wenander CS, Usher PA, Hebsgaard JB, Sondergaard BC, Rønø B, Mackay C, Friedrichsen B, Chang C, Tang R, Hornum L Clin Exp Immunol. 2014 Mar 25
Neutrophils release extracellular DNA traps in response to exercise. (2014) Beiter T, Fragasso A, Hudemann J, Schild M, Steinacker J, Mooren FC, Niess AM. Journal of Applied Physiology 2014 Aug 1;117(3):325-33. doi: 10.1152/japplphysiol.00173.2014
First-in-Human Phase I Study of the Liposomal RNA Interference Therapeutic Atu027 in Patients With Advanced Solid Tumors. (2014) Schultheis B, Strumberg D, Santel A, Vank C, Gebhardt F, Keil O, Lange C, Giese K, Kaufmann J, Khan M, Drevs J. J Clin Oncol. 2014 Nov 17. pii: JCO.2013.55.0376. [Epub ahead of print]
Effects of alcohol and polyphenols from beer on atherosclerotic biomarkers in high cardiovascular risk men: a randomized feeding trial (2014) Chiva-Blancha G, Magraner E, Condines X, Valderas-Martínez P, Roth I, Arranz S, Casa R, Navarro M, Hervas A, Sisó A, Martínez-Huélamo M, Vallverdú-Queralt A, Quifer-Rada P, Lamuela-Raventos R-M, Estruch R Elsevier - Nutrition, Metabolism and Cardiovascular Diseases 2014 Aug 2; doi: 10.1016/j.numecd.2014.07.008
Multi-analyte profiling of inflammatory mediators in COPD sputum – The effects of processing (2014) Pedersen F, Holz O, Lauer G, Quintini G, Kiwull-Schone H, Kirsten A-M, Magnussen H, Rabe KF, Goldmann T, Watz H Cytokine. 2014 Nov 15. doi:10.1016/j.cyto.2014.10.008
C-terminal region of teneurin-1 co-localizes with the dystroglycan complex in adult mouse testes and regulates testicular size and testosterone production (2014) Chand D, Colacci M, Dixon K, Kollara A, Brown TJ, Lovejoy DA Histochem Cell Biol. 2014 Feb;141(2):191-211
Phosphorylated tau-Aß42 Ratio as a Continuous Trait for Biomarker Discovery for Early-Stage Alzheimer's Disease in Multiplex Immunoassay Panels of Cerebrospinal Fluid. (2014) Harari O, Cruchaga C, Kauwe JS, Ainscough BJ, Bales K, Pickering EH, Bertelsen S, Fagan AM, Holtzman DM, Morris JC, Goate AM; Alzheimer’s Disease Neuroimaging Initiative Biol Psychiatry. 2014 Jan 19. pii: S0006-3223(14)00018-3
The Human Salivary Proteome is Radiation Responsive (2014) Moore HD, Ivey RG, Voytovich UJ, Lin C, Stirewalt DL, Pogosova-Agadjanyan EL, Paulovich AG Radiat Res. 2014 Apr 10. [Epub ahead of print]
Are Blood-Based Protein Biomarkers for Alzheimer's Disease also Involved in Other Brain Disorders? A Systematic Review (2014) Chiam JTW, Dobson RJB, Kiddle SJ, Sattlecker M Journal of Alzheimer's Disease 2014 Aug 5; 1875-8908 doi:10.3233/JAD-140816
Deferasirox effect on renal haemodynamic parameters in patients with transfusion-dependent ß thalassaemia. (2014) Piga A, Fracchia S, Lai ME, Cappellini MD, Hirschberg R, Habr D, Wegener A, Bouillaud E, Forni GL. Br J Haematol. 2014 Nov 17. doi: 10.1111/bjh.13217. [Epub ahead of print]
A multi-biomarker disease activity score tracks clinical response consistently in patients with rheumatoid arthritis treated with different anti-tumor necrosis factor therapies: A retrospective observational study (2014) Hirata S, Li W, Defranoux N, Cavet G, Bolce R, Yamaoka K, Saito K & Tanaka Y Mod Rheumatol.
An integrated omics analysis: impact of microgravity on host response to lipopolysaccharide in vitro (2014) Chakraborty N, Gautam A, Muhie S, Miller SA, Jett M, Hammamieh R. BMC Genomics 2014 Aug 7;15(1):659. [Epub ahead of print]
MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer. (2014) Powles T, Eder JP, Fine GD, Braiteh FS, Loriot Y, Cruz C, Bellmunt J, Burris HA, Petrylak DP, Teng SL, Shen X, Boyd Z, Hegde PS, Chen DS, Vogelzang NJ. Nature. 2014 Nov 26;515(7528):558-62. doi: 10.1038/nature13904.
Circulating Cytokines in Relation to the Extent and Composition of Coronary Atherosclerosis: Results from the Atheroremo-Ivus Study (2014) Battes LC, Cheng JM, Oemrawsingh RM, Boersma E, Garcia-Garcia HM, De Boer SPM, Buljubasic N, Mieghem NaV, Regar E, Geuns R-JV, Serruys PW, Akkerhuis KM, Kardys I Atherosclerosis
Comparison between Male and Female Sprague-Dawley Rats in the Response of Urinary Biomarkers to Injury Induced by Gentamicin (2014) Gautier JC, Gury T, Guffroy M, Masson R, Khan-Malek R, Hoffman D, Pettit S, Harpur E Toxicol Pathol. 2014 Apr 9. [Epub ahead of print]
Disrupted TH17/Treg Balance in Patients with Chronic Low Back Pain. (2014) Luchting B, Rachinger-Adam B, Zeitler J, Egenberger L, Möhnle P, Kreth S, Azad SC PLoS ONE 2014 Aug 14;9(8):e104883. doi: 10.1371/journal.pone.0104883
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. (2014) Herbst RS, Soria JC, Kowanetz M, Fine GD, Hamid O, Gordon MS, Sosman JA, McDermott DF, Powderly JD, Gettinger SN, Kohrt HE, Horn L, Lawrence DP, Rost S, Leabman M, Xiao Y, Mokatrin A, Koeppen H, Hegde PS, Mellman I, Chen DS, Hodi FS. Nature. 2014 Nov 26;515(7528):563-7. doi: 10.1038/nature14011.
Elevated Carbon Monoxide to Carbon Dioxide Ratio in the Exhaled Breath of Mice Treated with a Single Dose of Lipopolysaccharide (2014) Langeroudi AG, Hirsch CM, Estabragh AS, Meinardi S, Blake DR, Barbour AG Open Forum Infectious Diseases
Sequencing of Lrp2 Reveals Multiple Rare Variants Associated with Urinary Trefoil Factor-3 (2014) Mcmahon GM, Olden M, Garnaas M, Yang Q, Liu X, Hwang S-J, Larson MG, Consortium C, Goessling W, Fox CS Journal of the American Society of Nephrology
Pretreatment multi-biomarker disease activity score and radiographic progression in early RA: results from the SWEFOT trial (2014) Hambardzumyan K, Bolce R, Saevarsdottir S, Cruickshank S, Sasso E, Chernoff D, Forslind K, Petersson IF, Geborek P, van Vollenhoven RF Ann Rheum Dis.
Serum protein profiling reveals baseline and pharmacodynamic biomarker signatures associated with clinical outcome in mCRC patients treated with chemotherapy ± cediranib. (2014) Pommier AJ, Shaw R, Spencer SK, Morgan SR, Hoff PM, Robertson JD, Barry ST, Jürgensmeier JM. British Journal of Cancer 2014 Aug 14. doi: 10.1038/bjc.2014.436. [Epub ahead of print]
Cardiac mMCP-4+ mast cell expansion and elevation of IL-6, and CCR1/3 and CXCR2 signaling chemokines in an adjuvant-free mouse model of tree nut allergy. (2014) Gonipeta B, Para R, He Y, Srkalovic I, Ortiz T, Kim E, Parvataneni S, Gangur V. Immunobiology. 2014 Dec 2. pii: S0171-2985(14)00237-X. doi: 10.1016/j.imbio.2014.11.012. [Epub ahead of print]
Dipeptidyl Peptidase-4 Inhibition Improves Left Ventricular Function in Chronic Kidney Disease (2014) Connelly KA, Bowskill BB, Advani SL, Thai K, Chen L-H, Kabir MG, Gilbert RE, Advani A Clinical & Investigative Medicine
Evaluation of antidepressant properties of the p38 MAP kinase inhibitor losmapimod (GW856553) in Major Depressive Disorder: Results from two randomised, placebo-controlled, double-blind, multicentre studies using a Bayesian approach (2014) Inamdar A, Merlo-Pich E, Gee M, Makumi C, Mistry P, Robertson J, Steinberg E, Zamuner S, Learned S, Alexander R, Ratti E J Psychopharmacol. 2014 Apr 2. [Epub ahead of print]
Effects of acute inhalation of aerosols generated during resistance spot welding with mild-steel on pulmonary, vascular and immune responses in rats. (2014) Zeidler-Erdely PC, Meighan TG, Erdely A, Fedan JS, Thompson JA, Bilgesu S, Waugh S, Anderson S, Marshall NB, Afshari A, McKinney W, Frazer DG, Antonini JM. Inhalation Toxicology 2014 Aug 20:1-11. [Epub ahead of print]
Biomarkers of Central Nervous System Inflammation in Infantile and Juvenile Gangliosidoses. (2014) Utz JR, Crutcher T, Schneider J, Sorgen P, Whitley CB. Mol Genet Metab. 2014 Dec 6. pii: S1096-7192(14)00376-X. doi: 10.1016/j.ymgme.2014.11.015. [Epub ahead of print]
Evidence for disturbed insulin and growth hormone signaling as potential risk factors in the development of schizophrenia. (2014) van Beveren NJ, Schwarz E, Noll R, Guest PC, Meijer C, de Haan L, Bahn S. Translational Psychiatry 2014 Aug 26;4:e430. doi: 10.1038/tp.2014.52.
Assessment of serum biomarkers in rats after exposure to pesticides of different chemical classes. (2014) Moser VC, Stewart N, Freeborn DL, Crooks J, MacMillan DK, Hedge JM, Wood CE, McMahen RL, Strynar MJ, Herr DW. Toxicol Appl Pharmacol. 2014 Dec 9;282(2):161-174. doi: 10.1016/j.taap.2014.11.016. [Epub ahead of print]
The Role of Clusterin in Amyloid-B-Associated Neurodegeneration (2014) Desikan RS, Thompson WK, Holland D, Hess CP, Brewer JB, Zetterberg H, Blennow K, Andreassen OA, McEvoy LK, Hyman BT, Dale AM JAMA Neurology
Combined Inflammatory and Metabolic Defects Reflected by Reduced Serum Protein Levels in Patients with Buruli Ulcer Disease (2014) Phillips RO, Sarfo FS, Landier J, Oldenburg R, Frimpong M, Wansbrough-Jones M, Abass K, Thompson W, Forson M, Fontanet A, Niang F, Demangel C PLoS Negl Trop Dis. 2014 Apr 10;8(4):e2786
Chronic vagal stimulation for the treatment of low ejection fraction heart failure: results of the neural cardiac therapy for heart failure (NECTAR-HF) randomized controlled trial. (2014) Zannad F, De Ferrari GM, Tuinenburg AE, Wright D, Brugada J, Butter C, Klein H, Stolen C, Meyer S, Stein KM, Ramuzat A, Schubert B, Daum D, Neuzil P, Botman C, Caste MA, D'Onofrio A, Solomon SD1, Wold N, Ruble SB. European Heart Journal 2014 Aug 31. pii: ehu345. [Epub ahead of print]
Obesity superimposed on aging magnifies inflammation and delays the resolving response following myocardial infarction. (2014) Lopez EF, Kabarowski J, Ingle KA, Kain V, Barnes S, Crossman DK, Lindsey ML, Halade GV. Am J Physiol Heart Circ Physiol. 2014 Dec 5:ajpheart.00604.2014. doi: 10.1152/ajpheart.00604.2014. [Epub ahead of print]
Diets High in Protein or Saturated Fat Do Not Affect Insulin Sensitivity or Plasma Concentrations of Lipids and Lipoproteins in Overweight and Obese Adults (2014) Chiu S, Williams PT, Dawson T, Bergman RN, Stefanovski D, Watkins SM, Krauss RM Journal of Nutrition September 3, 2014, doi: 10.3945/?jn.114.197624
Citrus limonin glucoside supplementation decreased biomarkers of liver disease and inflammation in overweight human adults. (2014) Kelley DS, Adkins YC, Zunino SJ, Woodhouse LR, Bonnel EL, Breksa III AP, Manners GD, Mackey BE Journal of Functional Foods
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2013
Serum folate receptor alpha, mesothelin and megakaryocyte potentiating factor in ovarian cancer: association to disease stage and grade and comparison to CA125 and HE4 (2013) O'Shannessy DJ, Somers EB, Palmer LM, Thiel RP, Oberoi P, Heath R, Marcucci L Journal of Ovarian Research 2013, 6:29
Targeting oxidized LDL improves insulin sensitivity and immune cell function in obese Rhesus macaques (2013) Li S,Kievit P, Robertson A-K, Kolumam G. Li X, von Wachenfeldt K, Valfridsson C, Bullens S, Messaoudi I, Bader L, Cowan KJ, Kamath A, van Bruggen N, Bunting S, Frendéus B, Grove KL Molecular Metabolism, Available online 11 June 2013
Influence of Genetic Variation on Plasma Protein Levels in Older Adults Using a Multi-Analyte Panel (2013) Kim S, Swaminathan S, Inlow M, Risacher SL, Nho K, Shen L, Foroud TM, Petersen RC, Aisen PS, Soares H, Toledo JB, Shaw LM, Trojanowski JQ, Weiner MW, McDonald BC, Farlow MR, Ghetti B, Saykin AJ; Alzheimer’s Disease Neuroimaging Initiative (ADNI) PLoS One. 2013 Jul 23;8(7):e70269
Cigarette smoke induces molecular responses in respiratory tissues of ApoE-/- mice that are progressively deactivated upon cessation (2013) Boué S, De León H, Schlage WK, Peck MJ, Weiler H, Berges A, Vuillaume G, Martin F, Friedrichs B, Lebrun S, Meurrens K, Schracke N, Moehring M, Steffen Y, Schueller J, Vanscheeuwijck P, Peitsch MC, Hoeng J Toxicology, Available online 1 October 2013
Multi-analyte profile analysis of plasma immune proteins: altered expression of peripheral immune factors is associated with neuropsychiatric symptom severity in adults with and without chronic hepatitis C virus infection (2013) Huckans M, Fuller BE, Olavarria H, Sasaki AW, Chang M, Flora KD, Kolessar M, Kriz D, Anderson JR, Vandenbark AA, Loftis JM Brain and Behavior
The Link Between C-Reactive Protein and Alzheimer's Disease Among Mexican Americans (2013) O'Bryant SE, Johnson L, Edwards M, Soares H, Devous MD, Ross S, Rohlfing G, Hall J J Alzheimers Dis. 2013;34(3):701-6
RANTES has a potential to play a neuroprotective role in an autocrine/paracrine manner after ischemic stroke (2013) Tokamia H, Ago T, Sugimori H, Kuroda J, Awano H, Suzuki K, Kiyohara Y, Kamouchi M, Kitazono T Brain Research, Available online 18 April 2013
A phase II clinical trial of the Vascular Disrupting Agent BNC105P as second line chemotherapy for advanced Malignant Pleural Mesothelioma (2013) Nowak AK, Brown C, Millward MJ, Creaney J, Byrne MJ, Hughes B, Kremmidiotis G, Bibby DC, Leske AF, Mitchell PL, Pavlakis N, Boyer M, Stockler MR Lung Cancer. 2013 Jun 17. pii: S0169-5002(13)00218-3
Impact of Sunitinib on Human Thyroid Cancer Cells (2013) Grosse J, Warnke E, Pohl F, Magnusson NE, Wehland M, Infanger M, Eilles C, Grimm D Cell Physiol Biochem. 2013 Jul 12;32(1):154-170
Circulating Porphyromonas gingivalis lipopolysaccharide resets cardiac homeostasis in mice through a matrix metalloproteinase-9-dependent mechanism (2013) DeLeon-Pennell KY,de Castro Brás LE, Lindsey ML Physiological Reports Volume 1, Issue 5, October 2013
Applicability of rat precision-cut lung slices in evaluating nanomaterial cytotoxicity, apoptosis, oxidative stress, and inflammation (2013) Sauer UG, Vogel S, Aumann A, Hess A, Kolle SN, Ma-Hock L, Wohlleben W, Dammann M, Strauss V, Treumann S, Gröters S, Wiench K, van Ravenzwaay B, Landsiedel R Toxicol Appl Pharmacol. 2013 Dec 29. pii: S0041-008X(13)00570-X
The Ultra-Potent and Selective TLR8 Agonist VTX-294 Activates Human Newborn and Adult Leukocytes (2013) Dowling DJ, Tan Z, Prokopowicz ZM, Palmer CD, Matthews MA, Dietsch GN, Hershberg RM, Levy O PLoS One. 2013;8(3):e58164
Application of meta-analysis methods for identifying proteomic expression level differences (2013) Amess B, Kluge W, Schwarz E, Haenisch F, Alsaif M, Yolken RH, Leweke FM, Guest PC, Bahn S. Proteomics. 2013 Apr 14.
Urinary cystatin C as a renal biomarker and its immunohistochemical localization in anti-GBM glomerulonephritis rats (2013) Togashi Y, Imura N, Miyamoto Y Exp Toxicol Pathol. 2013 Jun 20. pii: S0940-2993(13)00076-6
Global chemokine expression in systemic sclerosis (SSc): CCL19 expression correlates with vascular inflammation in SSc skin (2013) Mathes AL, Christmann RB, Stifano G, Affandi AJ, Radstake TR, Farina GA, Padilla C, McLaughlin S, Lafyatis R Ann Rheum Dis. 2013 Jul 19
Suppression of Inflammation with Conditional Deletion of the Prostaglandin E2 EP2 Receptor in Macrophages and Brain Microglia (2013) Johansson JU, Pradhan S, Lokteva LA, Woodling NS, Ko N, Brown HD, Wang Q, Loh C, Cekanaviciute E, Buckwalter M, Manning-Bog AB, Andreasson KI J Neurosci. 2013 Oct 2;33(40):16016-16032
The Proton-Activated Receptor GPR4 Modulates Glucose Homeostasis by Increasing Insulin Sensitivity (2013) Giudici L, Velic A, Daryadel A, Bettoni C, Mohebbi N, Suply T, Seuwen K, Ludwig MG, Wagner CA Cell Physiol Biochem. 2013 Nov 28;32(5):1403-1416
Placebo-Controlled Randomized Clinical Trial on the Immunomodulating Activities of Low- and High-Dose Bromelain after Oral Administration – New Evidence on the Antiinflammatory Mode of Action of Bromelain (2013) Müller S, März R, Schmolz M, Drewelow B, Eschmann K, Meiser P Phytotherapy Research
Monitoring biomarkers after pediatric heart surgery: a new paradigm on the horizon (2013) Aqirbasli M, Undar A. Artif Organs. 2013 Jan;37(1):10-5.
Multiplexed protein profiling after bariatric surgery: characterization of improved endothelial dysfunction (2013) Bachmayer C, Hammes HP, Hasenberg T, Lammert A, Crowther D, Hess S Experimental and Clinical Endocrinology & Diabetes
Production of LPS-induced inflammatory mediators in murine peritoneal macrophages: neocuproine as a broad inhibitor and ATP7A as a selective regulator (2013) Patel OV, Wilson WB, Qin Z BioMetals, April 2013
LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys (2013) Adams AC, Halstead CA, Hansen BC, Irizarry AR, Martin JA, Meyers SR, Reynolds VL, Smith HW, Wroblewski VJ, Kharitonenkov A PLoS ONE 8(6): e65763
Elevated Carbon Monoxide in the Exhaled Breath of Mice during a Systemic Bacterial Infection (2013) Barbour AG, Hirsch CM, Ghalyanchi Langeroudi A, Meinardi S, Lewis ER, Estabragh AS, Blake DR PLoS One. 2013 Jul 31;8(7):e69802
The Innate Immune Response May Be Important For Surviving Plague In Wild Gunnison's Prairie Dogs (2013) Busch JD, Van Andel R, Stone NE, Cobble KR, Nottingham R, Lee J, VerSteeg M, Corcoran J, Cordova J, Van Pelt W, Shuey MM, Foster JT, Schupp JM, Beckstrom-Sternberg S, Beckstrom-Sternberg J, Keim P, Smith S, Rodriguez-Ramos J, Williamson JL, Rocke TE, Wagner DM Journal of Wildlife Diseases 2013 49:4, 920-931
Development of a small animal peripheral challenge model of Japanese encephalitis virus using interferon deficient AG129 mice and the SA14-14-2 vaccine virus strain (2013) Calvert AE, Dixon KL, Delorey MJ, Blair CD, Roehrig JT Vaccine. 2013 Nov 17. pii: S0264-410X(13)01533-8
Distinct Roles For Hepcidin and Interleukin 6 In The Recovery From Anemia Following Administration Of Heat-Killed Brucella Abortus (2013) Gardenghi S, Renaud TM, Meloni A, Casu C, Crielaard BJ, Bystrom LM, Greenberg-Kushnir N, Sasu BJ, Cooke KS, Rivella S Blood. 2013 Dec 19. [Epub ahead of print]
Pilot Study of Younger and Older Hiv-Infected Adults Using Traditional and Novel Functional Assessments (2013) Sandkovsky U, Robertson KR, Meza JL, High RR, Bonasera SJ, Fisher CM, Marsh AJ, Sheehy MK, Fox HS, Swindells S HIV Clinical Trials
Biomarkers of Alzheimer's Disease Among Mexican Americans (2013) O'Bryant SE, Xiao G, Edwards M, Devous M, Gupta VB, Martins R, Zhang F, Barber R J Alzheimers Dis. 2013 Jan 11. [Epub ahead of print]
Galectin-3 functions as an alarmin: pathogenic role for sepsis development in murine respiratory tularemia (2013) Mishra BB, Li Q, Steichen AL, Binstock BJ, Metzger DW, Teale JM, Sharma J PLoS One. 2013;8(3):e59616
Quantitative assessment of biological impact using transcriptomic data and mechanistic network models (2013) Thomson TM, Sewer A, Martin F, Belcastro V, Frushour B, Gebel S, Park J, Schlage WK, Talikka M, Vasilyev D, Westra JW, Hoeng J, Peitsch MC Toxicol Appl Pharmacol. 2013 Aug 7. pii: S0041-008X(13)00310-4
Maternal hematopoietic TNF, via milk chemokines, programs hippocampal development and memory (2013) Liu B, Zupan B, Laird E, Klein S, Gleason G, Bozinoski M, Gal Toth J, Toth M Nat Neurosci. 2013 Dec 1
C-Type Lectin Receptor Clec4d Plays a Protective Role in Resolution of Gram-Negative Pneumonia (2013) Steichen AL, Binstock BJ, Mishra BB, Sharma J Journal of Leukocyte Biology
Sweet Bing Cherries Lower Circulating Concentrations of Markers for Chronic Inflammatory Diseases in Healthy Humans (2013) Kelley DS, Adkins Y, Reddy A, Woodhouse LR, Mackey BE, Erickson KL J Nutr. 2013 Jan 23. [Epub ahead of print]
The effects of stress on hypothalamic-pituitary-adrenal (HPA) axis function in subjects with schizophrenia (2013) Guest FL, Martins-de-Souza D, Rahmoune H, Bahn S, Guest PC Rev Psiq Clín. 2013;40(1):20-7
A blood-based predictor for neocortical Aß burden in Alzheimer’s disease: results from the AIBL study (2013) Burnham SC, Faux NG, Wilson W, Laws SM, Ames D, Bedo J, Bush AI, Doecke JD, Ellis KA, Head R, Jones G, Kiiveri H, Martins RN, Rembach A, Rowe CC, Salvado O, Macaulay SL, Masters CL, Villemagne VL; Alzheimer’s Disease Neuroimaging Initiative; Australian Imaging, Biomarkers and Lifestyle Study Research Group Mol Psychiatry. 2013 Apr 30
Case study: the role of mechanistic network models in systems toxicology (2013) Hoeng J, Talikka M, Martin F, Sewer A, Yang X, Iskandar A, Schlage WK, Peitsch MC Drug Discovery Today, Available online 9 August 2013
Allogeneic mesenchymal stem cell infusion for the stabilization of focal segmental glomerulosclerosis (2013) Belingheri M, Lazzari L, Parazzi V, Groppali E, Biagi E, Gaipa G, Giordano R, Rastaldi MP, Croci D, Biondi A, Rebulla P, Edefonti A, Ghio L Biologicals. 2013 Oct 14. pii: S1045-1056(13)00111-5. doi: 10.1016/j.biologicals.2013.09.004
Transient inflammatory-like state and microbial dysbiosis are pivotal in establishment of mucosal homeostasis during colonisation of germ-free mice (2013) Aidy SE, Derrien M, Aardema R, Hooiveld G, Richards SE, Dane A, Dekker J, Vreeken R, Levenez F, Doré J, Zoetendal EG, van Baarlen P, Kleerebezem M Benef Microbes. 2013 Dec 9:1-11.
Update on the Safety and Efficacy of the Pan Class I Pi3k Inhibitor Sar245408 (Xl147) in Chronic Lymphocytic Leukemia and Non-Hodgkin’s Lymphoma Patients (2013) Davids MS, Rodon J, Abrisqueta P, Egile C, Ruiz-Soto R, Awan F Blood
Distinct Molecular Phenotypes in Male and Female Schizophrenia Patients (2013) Ramsey JM, Schwarz E, Guest PC, Van Beveren NJM, Leweke FM, Rothermundt M, Bogerts B, Steiner J, Bahn S PLoS ONE
#NAME? (2013) Kayadjanian N, Burghes A, Finkel RS, Mercuri E, Rouault F, Schwersenz I, Talbot Ka Orphanet Journal of Rare Diseases
Can changes in angiogenic biomarkers between the first and second trimesters of pregnancy predict development of pre-eclampsia in a low-risk nulliparous patient population? (2013) Myatt L, Clifton R, Roberts J, Spong C, Wapner R, Thorp J Jr, Mercer B, Peaceman A, Ramin S, Carpenter M, Sciscione A, Tolosa J, Saade G, Sorokin Y, Anderson G; for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network BJOG. 2013 Jan 18
Human and mouse neuroinflammation markers in Niemann-Pick disease, type C1 (2013) Cologna SM, Cluzeau CV, Yanjanin NM, Blank PS, Dail MK, Siebel S, Toth CL, Wassif CA, Lieberman AP, Porter FD. J Inherit Metab Dis. 2013 May 8.
Systemic sRAGE is a Biomarker of Emphysema and Associated with AGER Genetic Variants in COPD Patients (2013) Cheng DT, Kim DK, Cockayne DA, Belousov A, Bitter H, Cho, MH, Duvoix A, Edwards LD, Lomas DA, Miller BE, Reynaert N, Tal-Singer R, Wouters E, Agusti A, Fabbri LM, Rames A, Visvanathan S, Rennard SI, Jones P, Parmar H, MacNee W, Wolff G, Silverman EK, Mayer RJ, Pillai SG, and on Behalf of the TESRA and ECLIPSE Investigators American Journal of Respiratory And Critical Care Medicine ja (2013)
Integrative Omics Approach Identifies Interleukin-16 as a Biomarker of Emphysema (2013) Bowler RP, Bahr TM, Hughes G, Lutz S, Kim YI, Coldren CD, Reisdorph N, Kechris KJ OMICS. 2013 Oct 19. [Epub ahead of print]
Cytokine Profile Changes In 309 Myelofibrosis Patients: Comparison Of JAK1/JAK2 Inhibitor Therapy Vs. Placebo – Correlative Analysis From The Comfort-I Trial (2013) Dueck AC, Cleeland CS, Dantzer R, Sloan J, Verstovsek S, Emanuel RM, Geyer HL, Mesa RA Blood October 21, 2013 vol. 122 no. 21 4074
The effects of vitamin A on cells of innate immunity in vitro (2013) Wojtal K, Wolfram L, Frey-Wagner I, Lang S, Scharl M, Vavricka SR, Rogler G Toxicology in Vitro,
CXCL10 antagonism and plasma sDPPIV correlate with increasing liver disease in chronic HCV genotype 4 infected patients (2013) Ragab D, Laird M, Duffy D, Casrouge A, Mamdouh R, Abass A, Shenawy DE, Shebl AM, Elkashef WF, Zalata KR, Kamal M, Esmat G, Bonnard P, Fontanet A, Rafik M, Albert ML Cytokine. 2013 May 7. pii: S1043-4666(13)00181-6
IL-6 pathway-driven investigation of response to IL-6 receptor inhibition in rheumatoid arthritis (2013) Wang J, Platt A, Upmanyu R, Germer S, Lei G, Rabe C, Benayed R, Kenwright A, Hemmings A, Martin M, Harari O BMJ Open. 2013 Aug 19;3(8):e003199
Prognostic/predictive value of 207 serum factors in colorectal cancer treated with cediranib and/or chemotherapy (2013) Spencer SK, Pommier AJ, Morgan SR, Barry ST, Robertson JD, Hoff PM, Jürgensmeier JM Br J Cancer. 2013 Oct 22
Seasonal H3N2 influenza A virus fails to enhance Staphylococcus aureus co-infection in a non-human primate respiratory tract infection model (2013) Kobayashi SD, Olsen RJ, Lacasse RA, Safronetz D, Ashraf M, Porter AR, Braughton KR, Feldmann F, Clifton DR, Kash JC, Bailey JR, Gardner DJ, Otto M, Brining DL, Kreiswirth BN, Taubenberger JK, Parnell MJ, Feldmann H, Musser JM, Deleo FR Virulence. 2013 Oct 8;4(8). [Epub ahead of print]
Low Plasma Leptin in Cognitively Impaired ADNI Subjects: Gender Differences and Diagnostic and Therapeutic Potential (2013) Johnston J, Hu W, Fardo D, Greco S, Perry G, Montine T, Trojanowski J, Shaw L, Ashford J, Tezapsidis N, For The Alzheimer's Disease Neuroimaging Initiative Curr Alzheimer Res. 2013 Dec 11. [Epub ahead of print]
Identification of Subgroups of Schizophrenia Patients with Changes in Either Immune or Growth Factor and Hormonal Pathways (2013) Schwarz E, Van Beveren NJM, Ramsey J, Leweke FM, Rothermundt M, Bogerts B, Steiner J, Guest PC, Bahn S Schizophrenia Bulletin
SMA-MAP: A Plasma Protein Panel for Spinal Muscular Atrophy (2013) Kobayashi DT, Shi J, Stephen L, Ballard KL, Dewey R, Mapes J, Chung B, McCarthy K, Swoboda KJ, Crawford TO, Li R, Plasterer T, Joyce C; Biomarkers for Spinal Muscular Atrophy Study Group, Chung WK, Kaufmann P, Darras BT, Finkel RS, Sproule DM, Martens WB, McDermott MP, De Vivo DC; Pediatric Neuromuscular Clinical Research Network, Walker MG, Chen KS PLoS ONE 8(4): e60113.
EFFECTS OF CONTRAST MEDIA ON DIFFERENT URINARY BIOMARKERS OF KIDNEY INJURY (2013) Steffgen J, Blaschke S, Brun-Schulte-Wissing N, Pagel P, Huber F, Mapes J, Jaehnige A, Pestel S Nephrol. Dial. Transplant. (2013) 28 (suppl 1): i331-i351.
Intracellular Aggregation of Multimodal Silica Nanoparticles for (2013) Jokerst JV, Khademi C, Gambhir SS Sci Transl Med. 2013 Mar 20;5(177):177ra35
CSF protein biomarkers predicting longitudinal reduction of CSF ß-amyloid42 in cognitively healthy elders (2013) Mattsson N, Insel P, Nosheny R, Zetterberg H, Trojanowski JQ, Shaw LM, Tosun D, Weiner M Transl Psychiatry. 2013 Aug 20;3:e293
The ABCs of viral hepatitis that define biomarker signatures of acute viral hepatitis (2013) Duffy D, Saleh R, Laird M, Soneson C, Fouler LL, El-Daly M, Casrouge A, Decalf J, Abbas A, Eldin NS, Fontes M, Hamid MA, Mohamed MK, Rafik M, Fontanet, Albert, M. L. Hepatology
First-in-Human Phase I Study of PRS-050 (Angiocal), an Anticalin Targeting and Antagonizing VEGF-A, in Patients with Advanced Solid Tumors (2013) Mross K, Richly H, Fischer R, Scharr D, Büchert M, Stern A, Gille H, Audoly LP, Scheulen ME PLoS One. 2013 Dec 13;8(12):e83232
Mesenteric Ischemia-Reperfusion Injury up-Regulates Certain Cc, Cxc, and Xc Chemokines and Results in Multi-Organ Injury in a Time-Dependent Manner (2013) Jawa RS, Quist E, Boyer CW, Shostrom VK, Mercer DW European Cytokine Network
Susceptibility of adult and senescent Brown Norway rats to repeated ozone exposure: an assessment of behavior, serum biochemistry and cardiopulmonary function (2013) Gordon CJ, Jarema KA, Lehmann JR, Ledbetter AD, Schladweiler MC, Schmid JE, Ward WO, Kodavanti UP, Nyska A, Macphail RC. Inhal Toxicol. 2013 Feb;25(3):141-59.
Modulation of cardiometabolic pathways in skin and serum from patients with psoriasis (2013) Mehta NN, Li K, Szapary P, Krueger J, Brodmerkel C J Transl Med. 2013 Aug 22;11(1):194.
Carbon nanotube dosimetry: from workplace exposure assessment to inhalation toxicology (2013) Erdely A, Dahm M, Chen BT, Zeidler-Erdely PC, Fernback JE, Birch ME, Evans DE, Kashon ML, Deddens JA, Hulderman T, Bilgesu SA, Battelli L, Schwegler-Berry D, Leonard HD, McKinney W, Frazer DG, Antonini JM, Porter DW, Castranova V, Schubauer-Berigan MK Part Fibre Toxicol. 2013 Oct 21;10(1):53
Short sleep duration is associated with decreased serum leptin, increased energy intake, and decreased diet quality in postmenopausal women (2013) Stern JH, Grant AS, Thomson CA, Tinker L, Hale L, Brennan KM, Woods NF, Chen Z Obesity (Silver Spring). 2013 Dec 17
Reduced Bdnf Attenuates Inflammation and Angiogenesis to Improve Survival and Cardiac Function Following Myocardial Infarction in Mice (2013) Halade GV, Ma Y, Ramirez TA, Zhang J, Dai Q, Hensler JG, Lopez EF, Ghasemi O, Jin Y-F, Lindsey ML American Journal of Physiology - Heart and Circulatory Physiology
Leucine-Rich Repeat Kinase 2 (Lrrk2)-Deficient Rats Exhibit Renal Tubule Injury and Perturbations in Metabolic and Immunological Homeostasis (2013) Ness D, Ren Z, Gardai S, Sharpnack D, Johnson VJ, Brennan RJ, Brigham EF, Olaharski AJ PLoS ONE
Assessment of Inhibin B as a Biomarker of Testicular Injury Following Administration of Carbendazim, Cetrorelix, or 1,2-Dibromo-3-Chloropropane in Wistar Han Rats (2013) Moffit JS, Her LS, Mineo AM, Knight BL, Phillips JA, Thibodeau MS Birth Defects Research Part B Developmental and Reproductive Toxicology
Cytokines Associated with Increased Erythropoiesis in Sprague-Dawley Rats Administered a Novel Hyperglycosylated Analog of Recombinant Human Erythropoietin (2013) Andrews DA, Hamadeh HK, He YD, Boren BM, Turk JR, Boyce RW, Mytych DT, Barger TE, Salimi-Moosavi H, Sloey B, Elliott S, McElroy P, Sinclair AM, Shimamoto G, Pyrah IT, Lightfoot-Dunn RM Toxicol Pathol. 2013 May 14. [Epub ahead of print]
Increased accumulation of regulatory granulocytic myeloid cells in mannose receptor C type 1-deficient mice correlates with protection in a mouse model of neurocysticercosis (2013) Mishra PK, Morris EG, Garcia JA, Cardona AE, Teale JM Infect Immun. 2013 Apr;81(4):1052-63
Investigation of molecular serum profiles associated with predisposition to antipsychotic-induced weight gain (2013) Schwarz E, Steiner J, Guest PC, Bogerts B, Bahn S World J Biol Psychiatry. 2013 Sep 3. [Epub ahead of print]
Identification of a molecular profile associated with immune status in first onset schizophrenia patients (2013) Herberth M, Rahmoune H, Schwarz E, Koethe D, Harris LW, Kranaster L, Witt SH, Spain M, Barnes A, Schmolz M, Leweke MF, Guest PC, Bahn S Clin Schizophr Relat Psychoses
Protective role of Mincle in bacterial pneumonia by regulation of neutrophil mediated phagocytosis and extracellular trap formation (2013) Sharma A, Steichen AL, Jondle CN, Mishra BB, Sharma J J Infect Dis. 2013 Dec 17. [Epub ahead of print]
Biomarkers of Vascular Risk, Systemic Inflammation, and Microvascular Pathology and Neuropsychiatric Symptoms in Alzheimer's Disease. (2013) Hall JR, Wiechmann AR, Johnson LA, Edwards M, Barber RC, Winter AS, Singh M, O'Bryant SE. Journal of Alzheimer's Disease
Newborn screening for autism: in search of candidate biomarkers (2013) Mizejewski GJ, Lindau-Shepard B, Pass KA Biomark Med. 2013 Apr;7(2):247-60
Dose-related Differences in the Pharmacodynamic and Toxicologic Response to a Novel Hyperglycosylated Analog of Recombinant Human Erythropoietin in Sprague-Dawley Rats with Similarly High Hematocrit (2013) Andrews DA, Boren BM, Turk JR, Boyce RW, He YD, Hamadeh HK, Mytych DT, Barger TE, Salimi-Moosavi H, Sloey B, Elliott S, McElroy P, Sinclair AM, Shimamoto G, Pyrah IT, Lightfoot-Dunn RM Toxicol Pathol. 2013 May 14. [Epub ahead of print]
Preclinical Characterization of GLPG0634, a Selective Inhibitor of JAK1, for the Treatment of Inflammatory Diseases (2013) Van Rompaey L, Galien R, van der Aar EM, Clement-Lacroix P, Nelles L, Smets B, Lepescheux L, Christophe T, Conrath K, Vandeghinste N, Vayssiere B, De Vos S, Fletcher S, Brys R, van 't Klooster G, Feyen JH, Menet C J Immunol. 2013 Sep 4. [Epub ahead of print]
Impaired glycemia increases disease progression in mild cognitive impairment (2013) Morris JK, Vidoni ED, Honea RA, Burns JM Neurobiology of Aging, Available online 23 October 2013
Suppression of soluble T cell-associated proteins by an anti-interferon-a monoclonal antibody in adult patients with dermatomyositis or polymyositis (2013) Guo X, Higgs BW, Rebelatto M, Zhu W, Greth W, Yao Y, Roskos LK, White WI Rheumatology (Oxford). 2013 Dec 19
Ascending Dose-Controlled Trial of Beloranib, a Novel Obesity Treatment for Safety, Tolerability, and Weight Loss in Obese Women (2013) Hughes TE, Kim DD, Marjason J, Proietto J, Whitehead JP, Vath JE Obesity
Relationship between Plasma Analytes and SPARE-AD Defined Brain Atrophy Patterns in ADNI (2013) Toledo JB, Da X, Bhatt P, Wolk DA, Arnold SE, Shaw LM, Trojanowski JQ, Davatzikos C PLoS One. 2013;8(2):e55531
Chikungunya Virus-associated Long-term Arthralgia: A 36-month Prospective Longitudinal Study (2013) Schilte C, Staikovsky F, Couderc T, Madec Y, Carpentier F, Kassab S, Albert ML, Lecuit M, Michault A PLoS Negl Trop Dis. 2013 Mar;7(3):e2137
CD47 fusion protein targets CD172a+ cells in Crohn’s disease and dampens the production of IL-1ß and TNF (2013) Baba N, Van VQ, Wakahara K, Rubio M, Fortin G, Panzini B, Soucy G, Wassef R, Richard C, Tamaz R, Lahaie R, Bernard EJ, Caussignac Y, Leduc R, Lougnarath R, Bergeron C, Racicot MA, Bergeron F, Panzini MA, Demetter P, Franchimont D, Schäkel K, Weckbecker G, Kolbinger F, Heusser C, Huber T, Welzenbach K, Sarfati M J Exp Med. 2013 May 13. [Epub ahead of print]
Interleukin 17F Level and Interferon Beta Response in Patients With Multiple Sclerosis (2013) Hartung HP, Steinman L, Goodin DS, Comi G, Cook S, Filippi M, O'Connor P, Jeffery DR, Kappos L, Axtell R, Knappertz V, Bogumil T, Schwenke S, Croze E, Sandbrink R, Pohl C JAMA Neurol. 2013 Aug 1;70(8):1017-21
REG3-gamma-deficient mice have altered mucus distribution and increased mucosal inflammatory responses to the microbiota and enteric pathogens in the ileum (2013) Loonen LM, Stolte EH, Jaklofsky MT, Meijerink M, Dekker J, van Baarlen P, Wells JM Mucosal Immunol. 2013 Dec 18
Inflammatory Mediator Profiling Reveals Immune Properties of Chemotactic Gradients and Macrophage Mediator Production Inhibition During Thioglycollate Elicited Peritoneal Inflammation (2013) Lam D, Harris D, Qin Z Mediators of Inflammation
Analysis of a Urinary Biomarker Panel for Incident Kidney Disease and Clinical Outcomes (2013) O’Seaghdha CM, Hwang S-J, Larson MG, Meigs JB, Vasan RS, Fox CS Journal of the American Society of Nephrology
Plasma apolipoprotein A1 as a biomarker for parkinson's disease (2013) Qiang JK, Wong YC, Siderowf A, Hurtig HI, Xie SX, Lee VM, Trojanowski JQ, Yearout D, Leverenz J, Montine TJ, Stern M, Mendick S, Jennings D, Zabetian C, Marek K, Chen-Plotkin AS Ann Neurol. 2013 Feb 27
Clinical and Biochemical Differences in Patients Having Parkinson Disease With vs Without GBA Mutations (2013) Chahine LM, Qiang J, Ashbridge E, Minger J, Yearout D, Horn S, Colcher A, Hurtig HI, Lee V M-Y, Van Deerlin VM, Leverenz JB, Siderowf AD, Trojanowski JQ, Zabetian CP, Chen-Plotkin A JAMA Neurol. 2013;():1-7
A Multicenter Phase II Study of Single-agent Enzastaurin in Previously Treated Multiple Myeloma (2013) Jourdan E, Leblond V, Maisonneuve H, Benhadji KA, Hossain AM, Nguyen TS, Wooldridge JE, Moreau P Leuk Lymphoma. 2013 Nov 3. [Epub ahead of print]
The Senescence-Associated Secretory Phenotype In Multiple Myeloma (2013) Wildes TM, Paasch J, Fiala MA, Chen L, Vij R, Stockerl-Goldstein KE, Stewart S, Colditz GA,Tomasson M Blood October 21, 2013 vol. 122 no. 21 5357
Impact of Rheumatoid Arthritis Disease Activity Test on Clinical Practice (2013) Peabody JW, Strand V, Shimkhada R, Lee R, Chernoff D PLoS ONE
Clinical significance of plasma VEGF value in ischemic stroke - research for biomarkers in ischemic stroke (REBIOS) study (2013) Matsuo R, Ago T, Kamouchi M, Kuroda J, Kuwashiro T, Hata J, Sugimori H, Fukuda K, Gotoh S, Makihara N, Fukuhara M, Awano H, Isomura T, Suzuki K, Yasaka M, Okada Y, Kiyohara Y, Kitazono T BMC Neurol. 2013 Apr 8;13(1):32
Diabetic db/db mice exhibit central nervous system and peripheral molecular alterations as seen in neurological disorders (2013) Ernst A, Sharma AN, Elased KM, Guest PC, Rahmoune H, Bahn S Transl Psychiatry. 2013 May 28;3:e263
The role of LOX and LOXL2 in scar formation after glaucoma surgery (2013) Van Bergen T, Marshall D, Van de Veire S, Vandewalle E, Moons L, Herman J, Smith V, Stalmans I Invest Ophthalmol Vis Sci. 2013 Jul 2. pii: iovs.13-11696v1
Does ethnicity moderate dementia's biomarkers (2013) Royall DR, Palmer RF; Texas Alzheimer's Research and Care Consortium Neurobiol Aging. 2013 Sep 18. pii: S0197-4580(13)00340-0
Biomarker identification in serum samples from patients with recurrent cervical cancer treated with ADXS11-001 immunotherapy (2013) Molli P, Malinina I, Wallecha A Journal for ImmunoTherapy of Cancer 2013, 1(Suppl 1):P61
Multiplex immunoassay analysis of plasma shows prominent upregulation of growth factor activity pathways linked to GSK3ß signaling in bipolar patients (2013) Haenisch F, Alsaif M, Guest PC, Rahmoune H, Dickerson F, Yolken R, Bahn S Journal of Affective Disorders
Comparative inhalation toxicity of multi-wall carbon nanotubes, graphene, graphite nanoplatelets and low surface car (2013) Ma-Hock L, Strauss V, Treumann S, Küttler K, Wohlleben W, Hofmann T, Gröters S, Wiench K, van Ravenzwaay B, Landsiedel R Part Fibre Toxicol. 2013 Jun 17;10(1):23
Rg7212 Anti-Tweak Mab Inhibits Tumor Growth through Inhibition of Tumor Cell Proliferation and Survival Signaling and by Enhancing the Host Antitumor Immune Response (2013) Yin X, Luistro L, Zhong H, Smith M, Nevins T, Schostack K, Hilton H, Lin T-A, Truitt T, Biondi D, Wang X, Packman K, Rosinski J, Berkofsky-Fessler W, Tang J-P, Pant S, Geho D, Vega-Harring S, Demario M, Levitsky H, Simcox M American Association for Cancer Research
Development of a Multi-Biomarker Disease Activity Test for Rheumatoid Arthritis (2013) Centola M, Cavet G, Shen Y, Ramanujan S, Knowlton N, Swan KA, Turner M, Sutton C, Smith DR, Haney DJ, Chernoff D, Hesterberg LK, Carulli JP, Taylor PC, Shadick NA, Weinblatt ME, Curtis JR PLoS ONE
A multi-biomarker score measures rheumatoid arthritis disease activity in the BeSt study (2013) Hirata S, Dirven L, Shen Y, Centola M, Cavet G, Lems WF, Tanaka Y, Huizinga WJ and Allaart CF Rheumatology
Evaluation of Serum Biomarkers Associated with Radiographic Progression in Methotrexate-naive Rheumatoid Arthritis Patients Treated with Methotrexate or Golimumab (2013) Wagner C, Chen D, Fan H, Hsia EC, Mack M, Emery P, Fleischmann RM J Rheumatol. 2013 Mar 1. [Epub ahead of print]
Heart-type fatty acid binding protein and vascular endothelial growth factor: cerebrospinal fluid biomarker candidates for Alzheimer’s disease (2013) Guo L, Alexopoulos P, Perneczky R European Archives of Psychiatry and Clinical Neuroscience
Multi-analyte profiling and pathway analysis of plasma for proteins associated with cancer-related fatigue syndrome in disease-free breast cancer patients after primary treatment (2013) Minton O, Coulton GR, Stone P BMJ Support Palliat Care doi:10.1136/bmjspcare-2013-000452
Autoantibodies to Variable Heavy (VH) Chain Ig Sequences in Humans Impact the Safety and Clinical Pharmacology of a VH Domain Antibody Antagonist of TNF-a Receptor 1 (2013) Holland MC, Wurthner JU, Morley PJ, Birchler MA, Lambert J, Albayaty M, Serone AP, Wilson R, Chen Y, Forrest RM, Cordy JC, Lipson DA, Bayliffe AI Journal of Clinical Immunology, July 2013
Effects of cerebrospinal fluid proteins on brain atrophy rates in cognitively healthy older adults (2013) Mattsson N, Insel P, Nosheny R, Trojanowski JQ, Shaw LM, Jack Jr. CR, Tosun D, Weiner M, Alzheimer's Disease Neuroimaging Initiative Neurobiology of Aging, Available online 1 October 2013
Differential gene expression profile and altered cytokine secretion of thyroid cancer cells in space (2013) Ma X, Pietsch J, Wehland M, Schulz H, Saar K, Hübner N, Bauer J, Braun M, Schwarzwälder A, Segerer J, Birlem M, Horn A, Hemmersbach R, Waßer K, Grosse J, Infanger M, Grimm D FASEB J. 2013 Nov 6. [Epub ahead of print]
A Canonical Transforming Growth Factor Beta-Dependent Signaling Pathway is Present in Peripheral Blood Cells of Cancer Patients with Skeletal Metastasis (2013) Kadam S, Cleverly AL, Farmen M, Grondin J, Cox YI, Lahn M J Mol Biomark Diagn 2013, 4:3
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2012
Metabolic, hormonal and stress-related molecular changes in post-mortem pituitary glands from schizophrenia subjects (2012) Krishnamurthy D, Harris LW, Levin Y, Koutroukides TA, Rahmoune H, Pietsch S, Vanattou-Saifoudine N, Leweke FM, Guest PC, Bahn S World J Biol Psychiatry. 2012 Jan 17. [Epub ahead of print]
A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis (2012) Verstovsek S, Mesa RA, Gotlib J, Levy RS, Gupta V, DiPersio JF, Catalano JV, Deininger M, Miller C, Silver RT, Talpaz M, Winton EF, Harvey JH Jr, Arcasoy MO, Hexner E, Lyons RM, Paquette R, Raza A, Vaddi K, Erickson-Viitanen S, Koumenis IL, Sun W, Sandor V, Kantarjian HM N Engl J Med. 2012 Mar;366(9):799-807
First-Trimester Prediction of Preeclampsia in Nulliparous Women at Low Risk (2012) Myatt L, Clifton RG, Roberts JM, Spong CY, Hauth JC, Varner MW, Thorp JM Jr, Mercer BM, Peaceman AM, Ramin SM, Carpenter MW, Iams JD, Sciscione A, Harper M, Tolosa JE, Saade G, Sorokin Y, Anderson GD Obstet Gynecol. 2012 Jun;119(6):1234-1242
Proteomic analysis of the maternal protein restriction rat model for schizophrenia: Identification of translational changes in hormonal signalling pathways and glutamate neurotransmission (2012) Guest PC, Urday S, Ma D, Stelzhammer V, Harris LW, Amess B, Pietsch S, Oheim C, Ozanne SE, Bahn S Proteomics. 2012 Oct 16
Differences in the Association of Peripheral Insulin and Cognitive Function in Non-Diabetic Alzheimer's Disease Cases and Normal Controls (2012) Pavlik V, Massman P, Barber R, Doody R J Alzheimers Dis. 2012 Dec 14. [Epub ahead of print]
Characterization of a multiplex, 12-biomarker test for rheumatoid arthritis (2012) Eastman P.S, Manning WC, Qureshi F, Haney D, Cavet G, Alexander C, Hesterberg LK Pharm Biomed Anal.
Performance of a multi-biomarker score measuring rheumatoid arthritis disease activity in the CAMERA tight control study (2012) Bakker MF, Cavet G, Jacobs J, Bijlsma J, Haney DJ, Shen Y, Hesterberg LK, Smith D, Centola M, van Roon J, Lafeber F, Welsing P Ann Rheum Dis.
Preferential Replication of Systemically Delivered Oncolytic Vaccinia Virus in Focally Irradiated Glioma Xenografts (2012) Advani SJ, Buckel L, Chen NG, Scanderbeg DJ, Geissinger U, Zhang Q, Yu YA, Aguilar RJ, Mundt A, Szalay AA Clin Cancer Res. 2012 Feb 29. [Epub ahead of print]
Consumption of a High Monounsaturated-Fat Diet Reduces Oxidative Phosphorylation Gene Expression in Peripheral Blood Mononuclear Cells of Abdominally Overweight Men and Women (2012) van Dijk SJ, Feskens EJ, Bos MB, de Groot LC, de Vries JH, Müller M, Afman LA J Nutr. 2012 May 23. [Epub ahead of print]
Expanding the Psoriasis Disease Profile: Interrogation of the Skin and Serum of Patients with Moderate-to-Severe Psoriasis (2012) Suárez-Fariñas M, Li K, Fuentes-Duculan J, Hayden K, Brodmerkel C, Krueger JG J Invest Dermatol. 2012 Jul 5
Effects of Stimulation of Soluble Guanylate Cyclase on Diabetic Nephropathy in Diabetic eNOS Knockout Mice on Top of Angiotensin II Receptor Blockade (2012) Ott IM, Alter ML, von Websky K, Kretschmer A, Tsuprykov O, Sharkovska Y, Krause-Relle K, Raila J, Henze A, Stasch JP, Hocher B PLoS One. 2012;7(8):e42623. Epub 2012 Aug 10
Identification of factors associated with cancer related fatigue syndrome in disease-free breast cancer patients after completing primary treatment (2012) Minton O, Alexander S, Stone PC Breast Cancer Res Treat. 2012 Oct 14. [Epub ahead of print]
Characterization of immunologically active drugs in a novel organotypic co-culture model of the human gut and whole blood (2012) Schmohl M, Schneiderhan-Marra N, Baur N, Hefner K, Blum M, Stein GM, Joos TO, Schmolz M Int Immunopharmacol. 2012 Dec;14(4):722-8
Molecular Validation of the Acute Phencyclidine Rat Model for Schizophrenia: Identification of Translational Changes in Energy Metabolism and Neurotransmission*Journal of Proteome Research (2012) Ernst A, Ma D, Garcia-Perez I, Tsang TM, Kluge W, Schwarz E, Guest PC, Holmes E, Sarnyai Z, Bahn S Journal of Proteome Research
Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritis (2012) Zhao X, Qureshi F, Eastman P.S, Manning WC, Alexander C, Robinson WH, Hesterberg LK J Immunol Methods
Evaluation of multiple variate selection methods from a biological perspective: a nutrigenomics case study (2012) Tapp HS, Radonjic M, Kate Kemsley E, Thissen U Genes Nutr. 2012 Mar 2. [Epub ahead of print]
Analysis of serum and plasma identifies differences in molecular coverage, measurement variability and candidate biomarker selection (2012) Alsaif M, Guest PC, Schwarz E, Reif A, Kittel-Schneider S, Spain M, Rahmoune H, Bahn S Proteomics Clin Appl. 2012 May 29
A novel highly potent therapeutic antibody neutralizes multiple human chemokines and mimics viral immune modulation (2012) Scalley-Kim ML, Hess BW, Kelly RL, Krostag AR, Lustig KH, Marken JS, Ovendale PJ, Posey AR, Smolak PJ, Taylor JD, Wood CL, Bienvenue DL, Probst P, Salmon RA, Allison DS, Foy TM, Raport CJ PLoS One. 2012;7(8):e43332
DPP-4 Inhibition on Top of Angiotensin Receptor Blockade Offers a New Therapeutic Approach for Diabetic Nephropathy (2012) Altera ML, Ottb IM, von Webskyb K, Tsuprykovb O, Sharkovska Y, Krause-Relle K, Raila, J, Henze A, Klein T, Hocher B Kidney Blood Press Res 2012;36:119-130
Comparison of protein concentrations in serum versus plasma from Alzheimer’s patients (2012) Huebinger RM, Xiao G, Wilhelmsen KC, Diaz-Arrastia R, Zhang F, O’Bryant SE, Barber RC Advances in Alzheimer’s Disease Vol.1, No.3, 51-58 (2012)
Plasma biomarkers of depressive symptoms in older adults (2012) Arnold SE, Xie SX, Leung YY, Wang LS, Kling MA, Han X, Kim EJ, Wolk DA, Bennett DA, Chen-Plotkin A, Grossman M, Hu W, Lee VMY, Mackin RS, Trojanowski JQ, Wilson RS, Shaw LM Translational Psychiatry (2012) 2, e65;
A small animal peripheral challenge model of yellow fever using interferon-receptor deficient mice and the 17D-204 vaccine strain (2012) Thibodeaux BA, Garbinoa NC, Lissb NM, Piper J, Blair CD, Roehrig JT Vaccine
Association of Estimated Glomerular Filtration Rate and Urinary Uromodulin Concentrations with Rare Variants Identified by UMOD Gene Region Sequencing (2012) Köttgen A, Yang Q, Shimmin LC, Tin A, Schaeffer C, Coresh J, Liu X, Rampoldi L, Hwang S, Boerwinkle E, Hixson JE, Linda Kao WH, Fox CS PLoS ONE 7(5): e38311
Identification of blood protein biomarkers that aid in the clinical assessment of patients with malignant glioma (2012) Xu BJ, An QA, Srinivasa Gowda S, Yan W, Pierce LA, Abel TW, Rush SZ, Cooper MK, Ye F, Shyr Y, Weaver KD, Thompson RC Int J Oncol. 2012 Jun;40(6):1995-2003
Early Urinary and Plasma Biomarkers for Experimental Diabetic Nephropathy (2012) Alter ML, Kretschmer A, Von Websky K, Tsuprykov O, Reichetzeder C, Simon A, JP Stasch, Hoche B Clin. Lab. 2012;58:659-671
Neural progenitor cells regulate microglia functions and activity (2012) Mosher KI, Andres RH, Fukuhara T, Bieri G, Hasegawa-Moriyama M, He Y, Guzman R, Wyss-Coray T Nat Neurosci. 2012 Nov;15(11):1485-7
Sublytic Concentrations of Staphylococcus Aureus Panton-Valentine Leukocidin Alter Human Pmn Gene Expression and Enhance Bactericidal Capacity (2012) Graves SF, Kobayashi SD, Braughton KR, Whitney AR, Sturdevant DE, Rasmussen DL, Kirpotina LN, Quinn MT, Deleo FR Journal of Leukocyte Biology
RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents (2012) Xu D, Kim Y, Postelnek J, Vu MD, Hu DQ, Liao C, Bradshaw M, Hsu J, Zhang J, Pashine A, Srinivasan D, Woods J, Levin A, O'Mahony A, Owens TD, Lou Y, Hill RJ, Narula S, Demartino J, Fine JS J Pharmacol Exp Ther. 2012 Apr;341(1):90-103
Biomarkers and Depressive Symptoms in Older Women with and without Cognitive Impairment (2012) Hall JR, Johnson LA, Vo HT, Barber RC, Winter AS, O’Bryant SE Journal of Behavioral and Brain Science, 2012, 2, 276-281
Effects of red wine polyphenols and alcohol on glucose metabolism and the lipid profile: A randomized clinical trial (2012) Chiva-Blanch G, Urpi-Sarda M, Ros E, Valderas-Martinez P, Casas R, Arranz S, Guill?n M, Lamuela-Ravent?s RM, Llorach R, Andres-Lacueva C, Estruch R Clinical Nutrition (online September 3)
Associations between gonadotropins, testosterone and ß amyloid in men at risk of Alzheimer's disease (2012) Verdile G, Laws SM, Henley D, Ames D, Bush AI, Ellis KA, Faux NG, Gupta VB, Li QX, Masters CL, Pike KE, Rowe CC, Szoeke C, Taddei K, Villemagne VL, Martins RN Mol Psychiatry. 2012 Oct 23
Plasma biomarkers for Alzheimer's disease: much needed but tough to find (2012) Bazenet C, Lovestone S Biomark Med. 2012 Aug;6(4):441-54
Defining Map3 Kinases Required for Mda-Mb-231 Cell Tumor Growth and Metastasis (2012) Cronan MR, Nakamura K, Johnson NL, Granger DA, Cuevas BD, Wang JG, Mackman N, Scott JE, Dohlman HG, Johnson GL Oncogene
Bronchial and Bronchiolar Fibrosis in Rats Exposed to 2,3-Pentanedione Vapors: Implications for Bronchiolitis Obliterans in Humans (2012) Morgan DL, Jokinen MP, Price HC, Gwinn WM, Palmer SM, Flake GP Toxicol Pathol. 2012 Jan 3. [Epub ahead of print]
Inhibin B and luteinizing hormone levels in girls aged 6-11 years from NHANES III, 1988-1994 (2012) Sims EK, Addo OY, Gollenberg AL, Himes JH, Hediger ML, Lee PA Clin Endocrinol (Oxf). 2012 Mar 24
Evaluations of Tear Protein Markers in Dry Eye Disease: Repeatability of Measurement and Correlation with Disease (2012) Huang JF, Zhang Y, Rittenhouse KD, Pickering EH, McDowell MT Invest Ophthalmol Vis Sci. 2012 Jun 13. [Epub ahead of print]
Plasma Biomarkers Associated With the Apolipoprotein E Genotype and Alzheimer Disease (2012) Soares HD, Potter WZ, Pickering E, Kuhn M, Immermann FW, Shera DM, Ferm M, Dean RA, Simon AJ, Swenson F, Siuciak JA, Kaplow J, Thambisetty M, Zagouras P, Koroshetz WJ, Wan HI, Trojanowski JQ, Shaw LM; for the Biomarkers Consortium Alzheimer's Disease Plasma Proteomics Project Arch Neurol. 2012 Jul 16:1-8
Blood profiling of proteins and steroids during weight maintenance with manipulation of dietary protein level and glycaemic index (2012) Wang P, Holst C, Astrup A, Bouwman FG, van Otterdijk S, Wodzig WK, Andersen MR, van Baak MA, Rasmussen LG, Martinez JA, Jebb SA, Pfeiffer AF, Kafatos A, Handjieva-Darlenska T, Hlavaty P, Saris WH, Mariman EC Br J Nutr. 2012 Jan;107(1):106-19
Type I interferon and pattern recognition receptor signaling following particulate matter inhalation (2012) Erdely A, Antonini JM, Salmen-Muniz R, Liston A, Hulderman T, Simeonova PP, Kashon ML, Li S, Gu JK, Stone S, Chen BT, Frazer DG, Zeidler-Erdely PC Part Fibre Toxicol. 2012 Jul 9;9:25
Plasma Lipid Profiling across Species for the Identification of Optimal Animal Models of Human Dyslipidemia (2012) Yin W, Carballo-Jane E, Mclaren DG, Mendoza VH, Gagen K, Geoghagen NS, Mcnamara LA, Gorski JN, Eiermann GJ, Petrov A, Wolff M, Tong X, Wilsie LC, Akiyama TE, Chen J, Thankappan A, Xue J, Ping X, Andrews G, Wickham LA, Gai CL, Trinh T, Kulick AA, Donnelly MJ, Voronin GO, Rosa R, Cumiskey A-M, Bekkari K, Mitnaul LJ, Puig O, Chen F, Raubertas R, Wong PH, Hansen BC, Koblan KS, Roddy TP, Hubbard BK, Strack AM Journal of Lipid Research
Supernatants derived from chemotherapy-treated cancer cell lines can modify angiogenesis (2012) Liu WM, Dennis JL, Gravett AM, Chanthirakumar C, Kaminska E, Coulton G, Fowler DW, Bodman-Smith M, Dalgleish AG Br J Cancer. 2012 Jan 31 [Epub ahead of print]
Inflammation, organomegaly, and muscle wasting despite hyperphagia in a mouse model of burn cachexia (2012) Pedroso FE, Spalding PB, Cheung MC, Yang R, Gutierrez JC, Bonetto A, Zhan R, Chan HL, Namias N, Koniaris LG, Zimmers TA J Cachexia Sarcopenia Muscle. 2012 Mar 29
Interleukin-7 aggravated joint inflammation and tissue destruction in collagen-induced arthritis is associated with T-cell and B-cell activation (2012) Hartgring SA, Willis CR, Bijlsma JW, Lafeber FP, van Roon JA Arthritis Res Ther. 2012 Jun 7;14(3):R137
Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease (2012) Doecke JD, Laws SM, Faux NG, Wilson W, Burnham SC, Lam CP, Mondal A, Bedo J, Bush AI, Brown B, De Ruyck K, Ellis KA, Fowler C, Gupta VB, Head R, Macaulay SL, Pertile K, Rowe CC, Rembach A, Rodrigues M, Rumble R, Szoeke C, Taddei K, Taddei T, Trounson B, Ames D, Masters CL, Martins RN; for the Alzheimer's Disease Neuroimaging Initiative and Australian Imaging Biomarker and Lifestyle Research Group Arch Neurol. 2012 Jul 16:1-8
Serum Granulocyte Colony-Stimulating Factor and Alzheimer's Disease (2012) Barber RC, Edwards MI, Xiao G, Huebinger RM, Diaz-Arrastia R, Wilhelmsen KC, Hall JR, OBryant SE, for the Texas Alzheimer's Research and Care Consortium Dement Geriatr Cogn Disord Extra 2012;2:353-360
Intraindividual long term stability and response corridors of cytokines in healthy volunteers detected by a standardized whole-blood culture system for bed-side application (2012) Mueller SC, März R, Schmolz M, Drewelow B BMC Med Res Methodol. 2012 Aug 1;12(1):112
Proteomic approaches to unravel the complexity of schizophrenia (2012) Martins-de-Souza D, Guest PC, Rahmoune H, Bahn S Expert Rev Proteomics. 2012 Feb;9(1):97-108
Multivariate Protein Signatures of Pre-Clinical Alzheimer's Disease in the Alzheimer's Disease Neuroimaging Initiative (ADNI) Plasma Proteome Dataset (2012) Johnstone D, Milward EA, Berretta R, Moscato P PLoS One. 2012;7(4):e34341
Plasma apolipoprotein levels are associated with cognitive status and decline in a community cohort of older individuals (2012) Song F, Poljak A, Crawford J, Kochan NA, Wen W, Cameron B, Lux O, Brodaty H, Mather K, Smythe GA, Sachdev PS PLoS One. 2012;7(6):e34078
Urinary cystatin C as a biomarker for diabetic nephropathy and its immunohistochemical localization in kidney in Zucker diabetic fatty (ZDF) rats (2012) Togashi Y, Miyamoto Y Exp Toxicol Pathol. 2012 Jul 11
Toxicity Profile of Small-Molecule IAP Antagonist GDC-0152 is Linked to TNF-Alpha Pharmacology (2012) Erickson RI, Tarrant J, Cain G, Lewin-Koh SC, Dybdal N, Wong H, Blackwood E, West K, Steigerwalt R, Mamounas M, Flygare JA, Amemiya K, Dambach D, Fairbrother WJ, Diaz D Toxicol Sci. 2012 Sep 5. [Epub ahead of print]
Characterization of AQX-1125, a small molecule SHIP1 activator Part 2. Efficacy studies in allergic and pulmonary inflammation models in vivo (2012) Stenton GR, Mackenzie LF, Tam P, Cross JL, Harwig C, Raymond J, Toews J, Chernoff D, Macrury T, Szabo C Br J Pharmacol. 2012 Nov 2
STAT3 Is Activated by JAK2 Independent of Key Oncogenic Driver Mutations in Non-Small Cell Lung Carcinoma (2012) Looyenga BD, Hutchings D, Cherni I, Kingsley C, Weiss GJ, MacKeigan JP PLoS ONE 7(2): e30820
Somatic mutations in CCK2R alter receptor activity that promote oncogenic phenotypes (2012) Willard MD, Lajiness ME, Wulur IH, Feng B, Swearingen ML, Uhlik MT, Kinzler KW, Velculescu VE, Sjöblom T, Markowitz SD, Powell SM, Vogelstein B, Barber TD Mol Cancer Res. 2012 Apr 19
Photoacoustic Imaging of Mesenchymal Stem Cells in Living Mice via Silica-Coated Gold Nanorods (2012) Jokerst JV, Thangaraj M, Kempen P, Sinclair R, Gambhir SS ACS Nano. 2012 Jun 10. [Epub ahead of print]
Immunomodulatory Effect of the Topical Ophthalmic Janus Kinase Inhibitor Tofacitinib (CP-690,550) in Patients with Dry Eye Disease (2012) Huang JF, Yafawi R, Zhang M, McDowell M, Rittenhouse KD, Sace F, Liew SH, Cooper SR, Pickering EH Ophthalmology. 2012 Jul;119(7):e43-50
The Relation between Inflammation and Neuropsychological Test Performance (2012) Balldin VH, Hall JR, Barber RC, Hynan L, Diaz-Arrastia R, O’Bryant SE International Journal of Alzheimer’s Disease Volume 2012, Article ID 703871
Quantitative Proteomic Analysis of Niemann-Pick Disease, Type C1 Cerebellum Identifies Protein Biomarkers and Provides Pathological Insight (2012) Cologna SM, Jiang X-S, Backlund PS, Cluzeau CVM, Dail MK, Yanjanin NM, Siebel S, Toth CL, Jun H, Wassif CA, Yergey AL, Porter FD PLoS ONE 7(10): e47845
Targeting Tnf-? to Neoangiogenic Vessels Enhances Lymphocyte Infiltration in Tumors and Increases the Therapeutic Potential of Immunotherapy (2012) Calcinotto A, Grioni M, Jachetti E, Curnis F, Mondino A, Parmiani G, Corti A, Bellone M Journal of Immunology
Pharmacokinetics and Pharmacodynamics of Pegylated Interferon Lambda-1 in Cynomolgus Monkeys (2012) Byrnes-Blake KA, Pederson S, Klucher KM, Anderson-Haley M, Miller DM, Lopez-Talavera JC, Freeman JA J Interferon Cytokine Res. 2012 Jan 26. [Epub ahead of print]
Phase I Study of RO4929097, a Gamma Secretase Inhibitor of Notch Signaling, in Patients With Refractory Metastatic or Locally Advanced Solid Tumors (2012) Tolcher AW, Messersmith WA, Mikulski SM, Papadopoulos KP, Kwak EL, Gibbon DG, Patnaik A, Falchook GS, Dasari A, Shapiro GI, Boylan JF, Xu ZX, Wang K, Koehler A, Song J, Middleton SA, Deutsch J, Demario M, Kurzrock R, Wheler JJ J Clin Oncol. 2012 Apr 23
Plasma signaling proteins in persons at genetic risk for Alzheimer disease: influence of APOE genotype (2012) Ringman JM, Elashoff D, Geschwind DH, Welsh BT, Gylys KH, Lee C, Cummings JL, Cole GM Arch Neurol. 2012 Jun 1;69(6):757-64
Cerebrospinal fluid APOE levels, an endophenotype for genetic studies for Alzheimer's disease (2012) Cruchaga C, Kauwe JS, Nowotny P, Bales K, Pickering EH, Mayo K, Bertelsen S, Hinrichs A; the Alzheimer’s Disease Neuroimaging Initiative, Fagan AM, Holtzman DM, Morris JC, Goate AM Hum Mol Genet. 2012 Jul 20. [Epub ahead of print]
Markers of inflammation and bone remodelling associated with improvement in clinical response measures in psoriatic arthritis patients treated with golimumab (2012) Wagner CL, Visvanathan S, Elashoff M, McInnes IB, Mease PJ, Krueger GG, Murphy FT, Papp K, Gomez-Reino JJ, Mack M, Beutler A, Gladman D, Kavanaugh A Ann Rheum Dis. 2012 Sep 12. [Epub ahead of print]
Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aß amyloidosis (2012) Kim J, Eltorai AE, Jiang H, Liao F, Verghese PB, Kim J, Stewart FR, Basak JM, Holtzman DM J Exp Med. 2012 Nov 5. [Epub ahead of print]
Candidate Proteins, Metabolites and Transcripts in the Biomarkers for Spinal Muscular Atrophy (BforSMA) Clinical Study (2012) Finkel RS, Crawford TO, Swoboda KJ, Kaufmann P, Juhasz P, Li X, Guo Y, Li RH, Trachtenberg F, Forrest SJ, Kobayashi DT, Chen KS, Joyce CL, Plasterer T PLoS ONE 7(4): e35462
Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival (2012) Walter S, Weinschenk T, Stenzl A, Zdrojowy R, Pluzanska A, Szczylik C, Staehler M, Brugger W, Dietrich PY, Mendrzyk R, Hilf N, Schoor O, Fritsche J, Mahr A, Maurer D, Vass V, Trautwein C, Lewandrowski P, Flohr C, Pohla H, Stanczak JJ, Bronte V, Mandruzzato S, Biedermann T, Pawelec G, Derhovanessian E, Yamagishi H, Miki T, Hongo F, Takaha N, Hirakawa K, Tanaka H, Stevanovic S, Frisch J, Mayer-Mokler A, Kirner A, Rammensee HG, Reinhardt C, Singh-Jasuja H Nat Med. 2012 Jul 29. doi: 10.1038/nm.2883. [Epub ahead of print]
Cardiovascular risk factors, cortisol, and amyloid-ß deposition in Alzheimer's Disease Neuroimaging Initiative (2012) Toledo JB, Toledo E, Weiner MW, Jack CR Jr, Jagust W, Lee VM, Shaw LM, Trojanowski JQ; Alzheimer's Disease Neuroimaging Initiative Alzheimers Dement. 2012 Nov;8(6):483-9
Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Kidney Injury Molecule 1 (KIM-1) as Predictors of Incident CKD Stage 3: The Atherosclerosis Risk in Communities (ARIC) Study (2012) Bhavsar NA, Köttgen A, Coresh J, Astor BC Am J Kidney Dis. 2012 Apr 27. [Epub ahead of print]
Systemic Biomarkers of Neutrophilic Inflammation, Tissue Injury and Repair in COPD Patients with Differing Levels of Disease Severity (2012) Cockayne DA, Cheng DT, Waschki B, Sridhar S, Ravindran P, Hilton H, Kourteva G, Bitter H, Pillai SG, Visvanathan S, Müller KC, Holz O, Magnussen H, Watz H, Fine JS PLoS One. 2012;7(6):e38629
Single-agent lenalidomide in relapsed/refractory mantle cell lymphoma: results from a UK phase II study suggest activity and possible gender differences (2012) Eve HE, Carey S, Richardson SJ, Heise CC, Mamidipudi V, Shi T, Radford JA, Auer RL, Bullard SH, Rule SA Br J Haematol. 2012 Aug 9.
Evaluation of Plasma Proteomic Data for Alzheimer Disease State Classification and for the Prediction of Progression From Mild Cognitive Impairment to Alzheimer Disease (2012) Llano DA, Devanarayan V, Simon AJ; The Alzheimer’s Disease Neuroimaging Initiative (ADNI) Alzheimer Dis Assoc Disord. 2012 Sep 27
Mapping creatinine- and cystatin C-related white matter brain deficits in the elderly (2012) Rajagopalan P, Refsum H, Hua X, Toga AW, Jack CR Jr, Weiner MW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative Neurobiol Aging. 2012 Nov 19. pii: S0197-4580(12)00533-7
Moderate Alcohol Consumption Alters Both Leucocyte Gene Expression Profiles and Circulating Proteins Related to Immune Response and Lipid Metabolism in Men (2012) Joosten MM, Van Erk MJ, Pellis L, Witkamp RF, Hendriks HFJ British Journal of Nutrition
Plasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status (2012) Pellis L, van Erk MJ, van Ommen B, Bakker GCM, Hendriks HFJ, Cnubben NHP, Kleemann R, van Someren EP, Bobeldijk I, Rubingh CM, Wopereis S Metabolomics
Increased serum ß2-microglobulin is associated with clinical and immunological markers of disease activity in systemic lupus erythematosus (2012) Hermansen ML, Hummelshøj L, Lundsgaard D, Hornum L, Keller P, Fleckner J, Fox B, Poulsen LK, Jacobsen S Lupus. 2012 May 10. [Epub ahead of print]
A multicenter phase II study of single-agent enzastaurin in previously treated Waldenstrom macroglobulinemia (2012) Ghobrial IM, Moreau P, Harris B, Poon T, Jourdan E, Maisonneuve HM, Benhadji KA, Hossain A, Nguyen T, Wooldridge JE, Leblond V Clin Cancer Res. 2012 Aug 9
Plasma Based Markers of [(11)C] PiB-PET Brain Amyloid Burden (2012) Kiddle SJ, Thambisetty M, Simmons A, Riddoch-Contreras J, Hye A, Westman E, Pike I, Ward M, Johnston C, Lupton MK, Lunnon K, Soininen H, Kloszewska I, Tsolaki M, Vellas B, Mecocci P, Lovestone S, Newhouse S, Dobson R; for the Alzheimers Disease Neuroimaging Initiative PLoS One. 2012;7(9):e44260.
Adipocytokine signaling is altered in flinders sensitive line rats, and adiponectin correlates in humans with some symptoms of depression (2012) Wilhelm CJ, Choi D, Huckans M, Manthe L, Loftis JM Pharmacol Biochem Behav. 2012 Nov 12. pii: S0091-3057(12)00312-7
Plasma methionine sulfoxide in persons with familial Alzheimer's disease mutations (2012) Ringman JM, Fithian AT, Gylys K, Cummings JL, Coppola G, Elashoff D, Pratico D, Moskovitz J, Bitan G Dement Geriatr Cogn Disord. 2012;33(4):219-25
Biomarkers of Basic Activities of Daily Living in Alzheimer's Disease (2012) Hall JR, Johnson LA, Barber RC, Vo HT, Winter AS, O'Bryant SE J Alzheimers Dis. 2012 May 9. [Epub ahead of print]
Calcium/calmodulin-dependent protein kinase kinase 2 regulates macrophage-mediated inflammatory responses (2012) Racioppi L, Noeldner PK, Lin F, Arvai S, Means AR J Biol Chem. 2012 Feb 14. [Epub ahead of print]
Preferential Colonization of Metastases by Oncolytic Vaccinia Virus Strain GLV-1h68 in a Human PC-3 Prostate Cancer Model in Nude Mice (2012) Donat U, Weibel S, Hess M, Stritzker J, Härtl B, Sturm JB, Chen NG, Gentschev I, Szalay AA PLoS ONE 7(9): e45942
Electroconvulsive therapy exerts mainly acute molecular changes in serum of major depressive disorder patients (2012) Stelzhammer V, Guest PC, Rothermundt M, Sondermann C, Michael N, Schwarz E, Rahmoune H, Bahn S Eur Neuropsychopharmacol. 2012 Nov 22. pii: S0924-977X(12)00303-3
Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease (2012) Hu WT, Holtzman DM, Fagan AM, Shaw LM, Perrin R, Arnold SE, Grossman M, Xiong C, Craig-Schapiro R, Clark CM, Pickering E, Kuhn M, Chen Y, Van Deerlin VM, McCluskey L, Elman L, Karlawish J, Chen-Plotkin A, Hurtig HI, Siderowf A, Swenson F, Lee VM, Morris JC, Trojanowski JQ, Soares H; Alzheimer's Disease Neuroimaging Initiative Neurology. 2012 Aug 28;79(9):897-905
Dogs are more sensitive to antagonists of inhibitor of apoptosis proteins than rats and humans: a translational toxicokinetic/toxicodynamic analysis (2012) Wong H, Budha NR, West K, Blackwood E, Ware JA, Yu R, Darbonne WC, Gould SE, Steigerwalt R, Erickson R, Hop CE, LoRusso P, Eckhardt SG, Wagner A, Chan IT, Mamounas M, Flygare JA, Fairbrother WJ Toxicol Sci. 2012 Nov;130(1):205-13
Systemic immunoregulatory and proteogenomic effects of tacrolimus to sirolimus conversion in liver transplant recipients (2012) Levitsky J, Mathew JM, Abecassis M, Tambur A, Leventhal J, Chandrasekaran D, Herrera N, Al-Saden P, Gallon L, Abdul-Nabi A, Yang GY, Kurian SM, Salomon DR, Miller J Hepatology. 2012 Jan 11. doi: 10.1002/hep.25579. [Epub ahead of print]
Highly aggregated antibody therapeutics can enhance the in vitro innate and late-stage T-cell immune responses (2012) Joubert MK, Hokom M, Eakin C, Zhou L, Deshpande M, Baker MP, Goletz TJ, Kerwin BA, Chirmule N, Narhi LO, Jawa V J Biol Chem. 2012 Jul 20;287(30):25266-79
Proteins involved in extracellular matrix dynamics are associated with respiratory syncytial virus disease severity (2012) Schuurhof A, Bont L, Hodemaekers HM, de Klerk A, de Groot H, Hofland RW, van de Pol AC, Kimpen JL, Janssen R Eur Respir J. 2012 Jun;39(6):1475-81
Altered lung function relates to inflammation in an acute LPS mouse model (2012) Håkansson HF, Smailag A, Brunmark C, Miller-Larsson A, Lal H Pulmonary Pharmacology & Therapeutics
In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts (2012) Le Bihan MC, Bigot A, Jensen SS, Dennis J, Rogowska-Wrzesinska A, Lainé J, Gache V, Furling D, Jensen ON, Voit T, Mouly V, Coulton GR, Butler-Browne G J Proteomics. 2012 Sep 20. pii: S1874-3919(12)00652-5
Aging Exacerbates Obesity-Induced Oxidative Stress and Inflammation in Perivascular Adipose Tissue in Mice: A Paracrine Mechanism Contributing to Vascular Redox Dysregulation and Inflammation (2012) Bailey-Downs LC, Tucsek Z, Toth P, Sosnowska D, Gautam T, Sonntag WE, Csiszar A, Ungvari Z J Gerontol A Biol Sci Med Sci. 2012 Dec 3. [Epub ahead of print]
The kinetics of cardiopulmonary bypass: a dual-platform proteomics study of plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass (2012) Umstead TM, Lu CJ, Freeman WM, Myers JL, Clark JB, Thomas NJ, Icitovic N, Chinchilli VM, Undar A, Phelps DS Artif Organs. 2012 Jan;36(1):E1-E20.
Identification of blood-based molecular signatures for prediction of response and relapse in schizophrenia patients (2012) Schwarz E, Guest PC, Steiner J, Bogerts B, Bahn S Translational Psychiatry (2012) 2, e82
Identification of cis- regulatory variation influencing protein abundance levels in human plasma (2012) Lourdusamy A, Newhouse S, Lunnon K, Proitsi P, Powell J, Hodges A, Nelson SK, Stewart A, Williams S, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Lovestone S; on behalf of the AddNeuroMed Consortium, Dobson R; for the Alzheimer’s Disease Neuroimaging Initiative Hum Mol Genet. 2012 May 16. [Epub ahead of print]
Neuroinflammatory phenotype in early Alzheimer's disease (2012) Sudduth TL, Schmitt FA, Nelson PT, Wilcock DM Neurobiol Aging. 2012 Oct 9. pii: S0197-4580(12)00468-X
Molecular Sex Differences in Human Serum (2012) Ramsey JM, Schwarz E, Guest PC, van Beveren NJM, Leweke FM; Rothermundt M, Bogerts B, Steiner J, Ruta L, Baron-Cohen S, Bahn S PLoS ONE 7(12): e51504
Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis (2012) Burmester GR, Weinblatt ME, McInnes IB, Porter D, Barbarash O, Vatutin M, Szombati I, Esfandiari E, Sleeman MA, Kane CD, Cavet G, Wang B, Godwood A, Magrini F Ann Rheum Dis.
Validation of a Novel Multibiomarker Test to Assess Rheumatoid Arthritis Disease Activity (2012) Curtis Jr, van der Helm-van Mil ah, Knevel R, Huizinga TW, Haney DJ, Shen Y, Ramanujan S, Cavet G, Centola M, Hesterberg LK, Chernoff D, Ford K, Shadick N, Hamburger M, Fleischmann R, Keystone E, and Weinblatt ME Arthritis Care & Res.
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2011
Peripheral profiling analysis for bipolar disorder reveals markers associated with reduced cell survival (2011) Herberth M, Koethe D, Levin Y, Schwarz E, Krzyszton ND, Schoeffmann S, Ruh H, Rahmoune H, Kranaster L, Schoenborn T, Leweke MF, Guest PC, Bahn S Proteomics 11: 94-105.
The Role of Residual Gadolinium in the Induction of Nephrogenic Systemic Fibrosis-Like Skin Lesions in Rats (2011) Pietsch H, Raschke M, Ellinger-Ziegelbauer H, Jost G, Walter J, Frenzel T, Lenhard D, Hütter J, Sieber MA Invest Radiol. 46: 48-56.
Identifying Neuroimaging and Proteomic Biomarkers for MCI and AD via the Elastic Net (2011) Shen L, Kim S, Qi Y, Inlow M, Swaminathan S, Nho K, Wan J, Risacher SL, Shaw LM, Trojanowski JQ, Weiner M, Saykin AJ, ADNI Lecture Notes in Computer Science, 2011, Volume 7012/2011, 27-34
Exploratory analysis of multiple omics datasets using the adjusted RV coefficient (2011) Mayer CD, Lorent J, Horgan GW Stat Appl Genet Mol Biol. 2011;10(1):Article 14
Plasma clusterin and the risk of Alzheimer disease (2011) Schrijvers EM, Koudstaal PJ, Hofman A, Breteler MM JAMA. 305: 1322-6
Combining experimental and mathematical modeling to reveal mechanisms of macrophage-dependent left ventricular remodeling (2011) Jin YF, Han HC, Berger J, Dai Q, Lindsey ML BMC Syst Biol. 2011 May 5;5(1):60. [Epub ahead of print]
Tumor Microenvironment-Derived Proteins Dominate the Plasma Proteome Response During Breast Cancer Induction and Progression (2011) Pitteri SJ, Kelly-Spratt KS, Gurley KE, Kennedy J, Busald Buson T, Chin A, Wang H, Zhang Q, Wong CH, Chodosh LA, Nelson PS, Hanash SM, Kemp CJ Cancer Res. 2011 Jun 8. [Epub ahead of print]
STAT3 Activation in Skeletal Muscle Links Muscle Wasting and the Acute Phase Response in Cancer Cachexia (2011) Bonetto A, Aydogdu T, Kunzevitzky N, Guttridge DC, Khuri S, Koniaris LG, Zimmers TA PLoS ONE 6(7): e22538
Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease (2011) Zhang L, Rajan V, Lin E, Hu Z, Han HQ, Zhou X, Song Y, Min H, Wang X, Du J, Mitch WE FASEB J. 2011 May;25(5):1653-63
Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells (2011) Facciabene A, Peng X, Hagemann IS, Balint K, Barchetti A, Wang LP, Gimotty PA, Gilks CB, Lal P, Zhang L, Coukos G Nature. 2011 Jul 13;475(7355):226-30
Discrimination of agonist and antagonist forms of CXCL10 in biologic samples (2011) Casrouge A, Bisiaux A, Stephen L, Schmolz M, Mapes J, Pfister C, Pol S, Mallet V, Albert ML Clin Exp Immunol. 2012 Jan;167(1):137-48
Intratracheal instillation of cerium oxide nanoparticles induces hepatic toxicity in male Sprague-Dawley rats (2011) Nalabotu SK, Kolli MB, Triest WE, Ma JY, Manne NDPK, Katta A, Addagarla HS, Rice KM, Blough ER International Journal of Nanomedicine Volume 2011:6 Pages 2327 - 2335
Algorithm development for diagnostic biomarker assays (2011) Izmailov R, Guest PC, Bahn S, Schwarz E Int Rev Neurobiol. 2011;101:279-98
Growth Hormone and IGF-1 Deficiency Exacerbate High-Fat Diet-Induced Endothelial Impairment in Obese Lewis Dwarf Rats: Implications for Vascular Aging (2011) Bailey-Downs LC, Sosnowska D, Toth P, Mitschelen M, Gautam T, Henthorn JC, Ballabh P, Koller A, Farley JA, Sonntag WE, Csiszar A, Ungvari Z J Gerontol A Biol Sci Med Sci. 2011 Nov 10. [Epub ahead of print]
Comprehensive serum profiling for the discovery of epithelial ovarian cancer biomarkers (2011) Yip P, Chen TH, Seshaiah P, Stephen LL, Michael-Ballard KL, Mapes JP, Mansfield BC, Bertenshaw GP PLoS One. 2011;6(12):e29533. Epub 2011 Dec 21
Modulation of Inflammatory and Lipoprotein Pathways in Skin and Serum from Patients with Psoriasis (2011) Faha NNM, Li K, Szapary PO, Krueger J, Brodmerkel C J Am Coll Cardiol; 57: 576
Identification of Systemic Markers from A Pulmonary Carbon Nanotube Exposure (2011) Erdely A, Liston A, Salmen-Muniz R, Hulderman T, Shih-Houng Y, Zeidler-Erdely PC, Castranova V, Simeonova PP Journal of Occupational & Environmental Medicine: June 2011 - Volume 53 - Issue - p S80–S86
Mark B. Coventry Award: Synovial C-reactive Protein: A Prospective Evaluation of a Molecular Marker for Periprosthetic Knee Joint Infection (2011) Parvizi J, Jacovides C, Adeli B, Jung KA, Hozack WJ Clin Orthop Relat Res. 2011 Jul 23. [Epub ahead of print]
Urinary cystatin C as a biomarker for acute kidney injury and its immunohistochemical localization in kidney in the CDDP-treated rats (2011) Togashi Y, Sakaguchi Y, Miyamoto M, Miyamoto Y Exp Toxicol Pathol. 2011 Mar 4. [Epub ahead of print]
Deletion of a Malaria Invasion Gene Reduces Death and Anemia, in Model Hosts (2011) Gómez ND, Safeukui I, Adelani AA, Tewari R, Reddy JK, Rao S, Holder A, Buffet P, Mohandas N, Haldar K PLoS ONE 6(9): e25477
Relationship of neurocognitive deficits to diagnosis and symptoms across affective and non-affective psychoses (2011) Lewandowski KE, Cohen BM, Keshavan MS, Ongür D Schizophr Res. 2011 Oct 11. [Epub ahead of print]
Effects of DPP-4 Inhibitors on the Heart in a Rat Model of Uremic Cardiomyopathy (2011) Chaykovska L, von Websky K, Rahnenführer J, Alter M, Heiden S, Fuchs H, Runge F, Klein T, Hocher B PLoS ONE 6(11): e27861
Biomarkers and Depressive Symptoms in a Sample of Cognitively Intact and Alzheimer’s Disease Elderly Males (2011) Hall JR, Vo HT, Johnson LA, Winter S, Barber RC, O’Bryant SE Neuroscience & Medicine, 2011, 2, 306-312
Therapeutic vaccination with TG4010 and first-line chemotherapy in advanced non-small-cell lung cancer: a controlled phase 2B trial (2011) Quoix E, Ramlau R, Westeel V, Papai Z, Madroszyk A, Riviere A, Koralewski P, Breton JL, Stoelben E, Braun D, Debieuvre D, Lena H, Buyse M, Chenard MP, Acres B, Lacoste G, Bastien B, Tavernaro A, Bizouarne N, Bonnefoy JY, Limacher JM Lancet Oncol. 2011 Nov;12(12):1125-33
Bone Marrow Derived Mesenchymal Stromal Cells are Attracted by Multiple Myeloma Cell-Produced Chemokine CCL25 and Favor Myeloma Cell Growth In Vitro and In Vivo (2011) Xu S, Menu E, De Becker A, Van Camp B, Vanderkerken K, Van Riet I Stem Cells. 2011 Nov 18. [Epub ahead of print]
Assessment of Biomarkers of Drug-induced Kidney Injury in Cynomolgus Monkeys Treated with a Triple Re-uptake Inhibitor (2011) Guha M, Heier A, Price S, Bielenstein M, Caccese RG, Heathcote DI, Simpson TR, Stong DB, Bodes E Toxicol Sci. 2011 Jan 22. [Epub ahead of print]
A phase I safety study of enzastaurin plus bortezomib in the treatment of relapsed or refractory multiple myeloma (2011) Ghobrial IM, Munshi NC, Harris BN, Shi P, Porter NM, Schlossman RL, Laubach JP, Anderson KC, Desaiah D, Myrand SP, Wooldridge JE, Richardson PG, Abonour R Am. J. Hematol.
Molecular Markers for Diagnosis of Periprosthetic Joint Infection (2011) Jacovides CL, Parvizi J, Adeli B, Jung KA J Arthroplasty. 2011 May 12. [Epub ahead of print]
Relationship between pulmonary and systemic markers of exposure to multiple types of welding particulate matter (2011) Erdely A, Salmen-Muniz R, Liston A, Hulderman T, Zeidler-Erdely PC, Antonini JM, Simeonova PP Toxicology
Clinical and Plasma Proteomic Markers Correlating With Chronic Kidney Disease After Liver Transplantation (2011) Levitsky J, Salomon DR, Abecassis M, Langfelder P, Horvath S, Friedewald J, Wang E, Kurian SM, Mondala T, Gil S, McDade R, Ballard K, Gallon L Am J Transplant. 2011 Jul 27.
Modeling of pathological traits in Alzheimer's disease based on systemic extracellular signaling proteome (2011) Britschgi M, Rufibach K, Bauer Huang SL, Clark CM, Kaye JA, Li G, Peskind ER, Quinn JF, Galasko DR, Wyss-Coray T Mol Cell Proteomics. 2011 Jul 8. [Epub ahead of print]
Serum biomarkers of aging in the Brown Norway rat (2011) Gordon CJ, Rowsey PJ, Bishop BL, Ward WO, Macphail RC Exp Gerontol. 2011 Jul 28. [Epub ahead of print]
Mouse ghrelin-O-acyltransferase (GOAT) plays a critical role in bile acid reabsorption (2011) Kang K, Schmahl J, Lee JM, Garcia K, Patil K, Chen A, Keene M, Murphy A, Sleeman MW FASEB J. 2011 Sep 29. [Epub ahead of print]
Peripheral Blood Proteins Predict Mortality in Idiopathic Pulmonary Fibrosis (2011) Richards TJ, Kaminski N, Baribaud F, Flavin S, Brodmerkel C, Horowitz D, Li K, Choi J, Vuga LJ, Lindell KO, Klesen M, Zhang Y, Gibson KF Am J Respir Crit Care Med. 2011 Oct 20. [Epub ahead of print]
Direct evidence that GM-CSF inhalation improves lung clearance in pulmonary alveolar proteinosis (2011) Ohashi K, Sato A, Takada T, Arai T, Nei T, Kasahara Y, Motoi N, Hojo M, Urano S, Ishii H, Yokoba M, Eda R, Nakayama H, Nasuhara Y, Tsuchihashi Y, Kaneko C, Kanazawa H, Ebina M, Yamaguchi E, Kirchner J, Inoue Y, Nakata K, Tazawa R Respir Med. 2011 Nov 22. [Epub ahead of print]
Divergence Weighted Independence Graphs for the Exploratory Analysis of Biological Expression Data (2011) Xiang Y, Talikka M, Belcastro V, Sperisen P, Peitsch MC, Hoeng J, Whittaker J J Health Med Informat 2011, S2
Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-kappaB (2011) Taoufik E, Tseveleki V, Chu SY, Tselios T, Karin M, Lassmann H, Szymkowski DE, Probert L Brain. 2011 Sep;134(Pt 9):2722-35
G-protein-coupled receptor GPR21 knockout mice display improved glucose tolerance and increased insulin response (2011) Gardner J, Wu S, Ling L, Danao J, Li Y, Yeh WC, Tian H, Baribault H Biochemical and Biophysical Research Communications
Type I Interferons increase host susceptibility to Trypanosoma cruzi infection (2011) Chessler AD, Caradonna KL, Da'dara A, Burleigh BA Infect Immun. 2011 Mar 14. [Epub ahead of print]
Identification of a biological signature for schizophrenia in serum (2011) Schwarz E, Guest PC, Rahmoune H, Harris LW, Wang L, Leweke FM, Rothermundt M, Bogerts B, Koethe D, Kranaster L, Ohrmann P, Suslow T, McAllister G, Spain M, Barnes A, van Beveren NJ, Baron-Cohen S, Steiner J, Torrey FE, Yolken RH, Bahn S Mol Psychiatry. 2012 May;17(5):494-502
Human plasma inflammatory response during 5 days of exercise training in the heat (2011) Hailes WS, Slivka D, Cuddy J, Ruby BC Journal of Thermal Biology
Increased Disease Severity of Parasite-Infected TLR2-/- Mice Is Correlated with Decreased Central Nervous System Inflammation and Reduced Numbers of Cells with Alternatively Activated Macrophage Phenotypes in a Murine Model of Neurocysticercosis (2011) Gundra UM, Mishra BB, Wong K, Teale JM Infect Immun. 2011 Jul;79(7):2586-96
Early reactions of brain-derived neurotrophic factor in plasma (pBDNF) and outcome to acute antidepressant treatment in patients with Major Depression (2011) Dreimüller N, Schlicht KF, Wagner S, Peetz D, Borysenko L, Hiemke C, Lieb K, Tadic A Neuropharmacology. 2011 Jul 22. [Epub ahead of print]
Multi-analyte profiling reveals matrix metalloproteinase-9 and monocyte chemotactic protein-1 as plasma biomarkers of cardiac aging (2011) Chiao YA, Dai Q, Zhang J, Lin J, Lopez EF, Ahuja SS, Chou YM, Lindsey ML, Jin YF Circ Cardiovasc Genet. 2011 Aug 1;4(4):455-62
Comparison of the course of biomarker changes and kidney injury in a rat model of drug-induced acute kidney injury (2011) Sasaki D, Yamada A, Umeno H, Kurihara H, Nakatsuji S, Fujihira S, Tsubota K, Ono M, Moriguchi A, Watanabe K, Seki J Biomarkers. 2011 Sep 28. [Epub ahead of print]
Short term inhalation toxicity of a liquid aerosol of CdS/Cd(OH)(2) core shell quantum dots in male Wistar rats (2011) Ma-Hock L, Brill S, Wohlleben W, Farias PM, Chaves CR, Tenório DP, Fontes A, Santos BS, Landsiedel R, Strauss V, Treumann S, van Ravenzwaay B Toxicol Lett. 2011 Oct 20. [Epub ahead of print]
A novel detection method of non-small cell lung cancer using multiplexed bead-based serum biomarker profiling (2011) Lee HJ, Kim YT, Park PJ, Shin YS, Kang KN, Kim Y, Kim CW J Thorac Cardiovasc Surg. 2011 Nov 18. [Epub ahead of print]
Biomarkers for drug-induced renal damage and nephrotoxicity-an overview for applied toxicology (2011) Fuchs TC, Hewitt P AAPS J. 2011 Dec;13(4):615-31
Treatment of experimental anterior and intermediate uveitis by a dexamethasone intravitreal implant (2011) Ghosn CR, Li Y, Orilla WC, Lin T, Wheeler L, Burke JA, Robinson MR, Whitcup SM Invest Ophthalmol Vis Sci. 2011 May 2;52(6):2917-23
High tumor levels of IL6 and IL8 abrogate preclinical efficacy of the gamma-secretase inhibitor, RO4929097 (2011) He W, Luistro L, Carvajal D, Smith M, Nevins T, Yin X, Cai J, Higgins B, Kolinsky K, Rizzo C, Packman K, Heimbrook D, Boylan JF Molecular Oncology [Epub ahead of print]
Homozygous mutation in SAMHD1 gene causes cerebral vasculopathy and early onset stroke (2011) Xin B, Jones S, Puffenberger EG, Hinze C, Bright A, Tan H, Zhou A, Wu G, Vargus-Adams J, Agamanolis D, Wang H Proc Natl Acad Sci U S A. 2011 Mar 14. [Epub ahead of print]
Inhalation exposure of gas-metal arc stainless steel welding fume increased atherosclerotic lesions in apolipoprotein E knockout mice (2011) Erdely A, Hulderman T, Salmen-Muniz R, Liston A, Zeidler-Erdely PC, Chen BT, Stone S, Frazer DG, Antonini JM, Simeonova PP Toxicol Lett. 2011 Jul 4;204(1):12-6.