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Assay Change Log

This page contains an up-to-date list of the important changes to RBM’s products and assays. These changes are made as part of our ongoing efforts to improve the quality of our assays and the data we provide. We strive to deliver superior services by emphasizing reliable data and aim to make customers aware of information that may impact their projects as soon as possible.

 

If you have questions about any of the items contained in the following tables, please contact RBM’s Client Services team.

 

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Assay Change Log

2024

Assay or Product Description of Change Effective Date
Glycoprotein non-metastatic melanoma protein B (GPNMB) Assay added to service offerings. 6/19/2024
Triggering receptor expressed on myeloid cells-1 Simoa (TREM1) Assay added to service offerings 6/5/2024
Human Epidermal Growth Factor Receptor 2 (HER-2) Assay redeveloped using new capture and detection antibodies and assay blocker formulation adjusted 5/1/2024
Kallkrien 5 Assay did not meet performance specifications in EDTA plasma and assay blocker formulation adjusted 5/1/2024
Insulin-like Growth Factor-Binding Protein 1 (IGFBP-1) Assay blocker formulation adjusted 5/1/2024
Vascular Endothelial Growth Factor Receptor 1 (VEGFR-1) Assay blocker formulation adjusted 5/1/2024
Phospho-Tau217 Simoa (pTau217) Assay added to service offerings 4/16/2024
Immunoglobulin A (IgA) Assay moved to simplex 3/8/2024
Neurofilament heavy polypeptide (pNF-H) Assay added to service offerings 2/28/2024
Endoglin Removed from service offerings 2/13/2024
Macrophage inflammatory protein 3 beta (MIP-3 beta) Assay was redeveloped using a new capture and detection antibody 1/23/2024
Interleukin-12 Subunit p70 (IL-12p70) Assay moved to a different multiplex 1/4/2024
Interleukin-12 Subunit p40 (IL-12p40) Assay moved to a different multiplex 1/4/2024

2023

Assay or Product Description of Change Effective Date
Progranulin Assay added to service offerings 12/21/2023
Phospho-Tau181 (pTau181) Assay added to service offerings 10/23/2023
Thyroid-Stimulating Hormone (TSH) Assay was redeveloped using new capture and detection antibodies 10/10/2023
Myeloid cell surface antigen CD33 Assay added to service offerings 8/30/2023
Interferon gamma Induced Protein 10 (IP-10, HMPC111) Multiplex dilution adjusted 7/28/2023
Interleukin-1 receptor antagonist (IL-1ra, HMPC111) Multiplex dilution adjusted 7/28/2023
Interleukin-2 receptor alpha (IL-2 receptor alpha, HMPC111) Multiplex dilution adjusted 7/28/2023
Matrix Metalloproteinase-3 (MMP-3, HMPC111) Multiplex dilution adjusted 7/28/2023
MHC class I chain-related protein A (MICA, HMPC111) Multiplex dilution adjusted 7/28/2023
Monocyte Chemotactic Protein 2 (MCP-2, HMPC111) Multiplex dilution adjusted 7/28/2023
Monokine Induced by Gamma Interferon (MIG, HMPC111) Multiplex dilution adjusted 7/28/2023
Epidermal Growth Factor Receptor (EGFR) assay moved to simplex and redeveloped using a new detection antibody 7/25/2023
Glucagon-like Peptide 1, total (GLP-1, total) assay moved to simplex and was redeveloped using a new detection antibody 7/17/2023
Beta Amyloid 42 Simoa (AB20 Simoa) Assay added to service offerings 7/11/2023
Beta Amyloid 40 Simoa (AB40 Simoa) Assay added to service offerings 7/7/2023
Periostin (Fibrosis) Assay has been removed from service offerings 7/7/2023
Hepatocyte Growth Factor receptor (HGF) Multiplex dilution adjusted 6/14/2023
Luteinizing Hormone (LH) Assay removed from service offerings 6/2/2023
Haptoglobin Assay redeveloped using new capture and detection antibodies 4/4/2023
Vitamin D-Binding Protein (VDBP) Assay redeveloped using new capture antibody 4/4/2023
Tau Assay added to service offerings. 3/9/2023
B cell-activating factor (BAFF) Assay did not meet specifications in EDTA plasma and results should be used for information purposes only. 2/28/2023
Intercellular Adhesion Molecule 1 (ICAM-1) Assay was redeveloped using a new capture antibody (HMPC111) 2/28/2023
Antithrombin-III (AT-III) Assay moved to simplex. 2/27/2023
Thrombin-Activatable Fibrinolysis Inhibitor (TAFI) Assay moved to simplex. 2/27/2023

2022

Assay or Product Description of Change Effective Date
6Ckine Assay moved to a different multiplex. 11/14/2022
Cancer Antigen 15-3 (CA-15-3) Assay moved to a different multiplex. 11/14/2022
Stromal cell-derived factor-1 (SDF-1) Assay moved to a different multiplex. 11/14/2022
Apolipoprotein A-I (Apo AI) Assay was removed from service offerings. 7/21/2022
Apolipoprotein A-II (Apo AII) Assay was removed from service offerings. 7/21/2022
Apolipoprotein C-I (Apo C-I) Assay was removed from service offerings. 7/21/2022
Apolipoprotein C-III (Apo C-III) Assay was removed from service offerings. 7/21/2022
Apolipoprotein H (Apo H) Assay was removed from service offerings. 7/21/2022
Transthyretin (TTR) Assay was removed from service offerings. 7/21/2022
Microalbumin (Albumin) Assay was removed from service offerings. 7/14/2022
Microalbumin (Albumin) Assay was removed from service offerings. 7/14/2022
Matrix Metalloproteinase-9, total (MMP-9, total) Assay was removed from service offerings. 6/21/2022
CD40 Ligand (CD40L) Assay was redeveloped using a new capture and detection antibodies. 1/19/2022

2021

Assay or Product Description of Change Effective Date
Albumin (Alb) Assay redeveloped using new beads, detection standard and blocker formulation. 11/29/2021
Human DiscoveryMAP Gastric inhibitory polypeptide, Glycogen phosphorylase isoenzyme BB, Leptin Receptor, Paraoxanase-1, Omentin, Visceral adipose tissue – derived serpin A12, Visfatin, Complement Factor H, Complement Factor H – Related Protein 1, Transferrin receptor protein 1, C-C motif chemokine 15 (CCL15), C-Peptide, Nerve Growth Factor beta were removed from product. 11/3/2021
Human NeuroMAP Complement Factor H, Complement Factor H – Related Protein 1, Transferrin receptor protein 1, and Nerve growth factor beta were removed from product. 11/3/2021
I-309 (C-C motif chemokine ligand I) (I-309 Luminex) Luminex assay was removed from service offerings. 9/27/2021
Microalbumin (ALB) Assay was redeveloped using new beads, detection standard and blocker formulation. 9/14/2021
Interleukin-31 (IL-31 Luminex) Assay removed from service offerings. 7/8/2021
Interleukin-22 (IL-22) Assay unit updated. 7/8/2021
Collagen IV (Collagen IV) Assay removed from service offerings. 7/7/2021
Interleukin-1 beta Simoa (IL-1 beta Simoa) Assay was redeveloped using a new standard and sample diluent. 5/24/2021
Macrophage Inflammatory Protein-1 beta (MIP-1 beta) Assay moved to a different multiplex. 4/28/2021
Elafin (Elafin) Assay has been added to service offerings. 4/26/2021
Glial Fibrillary Acidic Protein Simoa (GFAP Simoa) Assay added to service offerings. 3/26/2021
Fibroblast Growth Factor 23 Simoa (FGF-23 Simoa) Assay added to service offerings. 3/18/2021
Interleukin-17F Simoa (IL-17F Simoa) Assay added to service offerings. 3/18/2021
Interleukin-17F Simoa (IL-17F Simoa) Assay did not meet specifications for antibody competition in EDTA plasma and results should be used for information purposes only 3/18/2021
Granzyme B Simoa (Granzyme B Simoa) Assay added to service offerings. 2/1/2021
Human DiscoveryMAP Apolipoprotein D was removed from product. 1/28/2021
Human NeuroMAP Apolipoprotein D was removed from product. 1/28/2021
Human CardiovascularMAP Apolipoprotein D was removed from product. 1/28/2021
Complement Factor H (CFH) Assay added to service offerings. 1/12/2021

2020

Assay or Product Description of Change Effective Date
Matrix Metalloproteinase-10 (MMP-10) Assay moved to a different multiplex. 12/23/2020
Complement Factor H (CFH) Assay removed from service offerings. 12/7/2020
Alpha 1 Microglobulin (A1M) Assay removed from service offerings. 11/17/2020
Alpha 2 Macroglobulin (A2M) Assay was redeveloped using a new competitor and standard antigen. 11/4/2020
Progranulin (Progranulin) Assay removed from service offerings. 10/30/2020
HE4 (HE4) Assay removed from service offerings. 10/30/2020
Interleukin-1 receptor type 1 (IL-R1) Assay does not meet performance specifications in serum. 10/26/2020
Immunoglobulin E (IgE) Assay added to service offerings. 10/20/2020
Interleukin-23 Simoa (IL-23 Simoa) Assay added to service offerings. 9/16/2020
Interleukin-15 (IL-15) Assay was redeveloped and moved to a different multiplex. 9/11/2020
Myeloid Progenitor Inhibitory Factor 1 (MPIF-1) Assay was redeveloped and moved to a different multiplex. 8/20/2020
Programmed Cell Death Protein 1 Simoa (PD-1 Simoa) Assay added to service offerings. 7/23/2020
Programmed Death-Ligand 1 Simoa (PD-L1 Simoa) Assay added to service offerings. 7/14/2020
Interleukin-2 receptor alpha (IL-2 receptor alpha) Assay moved to a different multiplex. 6/29/2020
Latency-Associated Peptide of Transforming Growth Factor beta 1 (LAP-TGF-b1) Assay moved to a different multiplex. 6/29/2020
Latency-Associated Peptide of Transforming Growth Factor beta 1 (LAP-TGF-b1) Assay meets specifications in serum. 6/29/2020
Eotaxin-2 Assay moved to a different multiplex. 6/29/2020
Eotaxin-2 Assay meets specifications in EDTA plasma. 6/29/2020
Interleukin-15 (IL-15) Assay removed from service offerings. 6/29/2020
B Lymphocyte Chemoattractant (BLC) Assay removed from Luminex service offerings 6/25/2020
Insulin-like Growth Factor-Binding Protein 2 (IGFBP-2) Multiplex dilution adjusted 6/22/2020
Macrophage Migration Inhibitory Factor (MIF) Multiplex dilution adjusted 6/22/2020
Eotaxin-3 Multiplex dilution adjusted 6/22/2020
Angiopoietin-2 (Ang-2) Multiplex dilution adjusted 6/22/2020
Aggrecan Core Protein (Aggrecan) Assay removed from service offerings. 6/15/2020
Interleukin-21 Simoa (IL-21 Simoa) Assay added to service offerings. 6/9/2020
Chromogranin-A (CgA) Assay removed from service offerings. 5/29/2020
Nerve Growth Factor beta (NGF-beta) Assay moved to a different multiplex. 5/29/2020
Eotaxin-2 Assay does not meet performance specifications in EDTA plasma. 5/19/2020
Latency-Associated Peptide of Transforming Growth Factor beta 1 (LAP-TGF-b1) Assay does not meet performance specifications in serum. 5/19/2020
T Lymphocyte-secreted protein I-309 Simoa (I-309 Simoa) Assay added to service offerings. 5/12/2020
Human OncologyMAP Epithelial cell adhesion molecule, Protein S100 A6, and Glucose 6 phosphate isomerase, A disintegrin and metalloproteinase with thrombospondin motifs 8, Folate receptor gamma, and Aggrecan core protein removed from product. . 5/11/2020
Human DiscoveryMAP Epithelial cell adhesion molecule, Protein S100 A6, and Glucose 6 phosphate isomerase, A disintegrin and metalloproteinase with thrombospondin motifs 8, Folate receptor gamma, and Aggrecan core protein removed from product. 5/11/2020
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) Assay discontinued from human services. 3/31/2020
Sex Hormone Binding Globulin (SHBG) Assay added to service offerings. 3/20/2020
Metalloproteinase-10 (MMP-10) Assay discontinued from human services. 2/27/2020
Interferon-lambda 1 Simoa (IFN-lambda 1 Simoa) Assay added to service offerings. 2/27/2020
IL-22 Simoa Assay added to service offerings. 2/25/2020
IL-12p70 Simoa Assay added to service offerings. 2/25/2020
Human DiscoveryMAP Assay moved to a different multiplex. 1/21/2020
Human OncologyMAP CD5 Antigen like, Fetuin-A, Vitamin K Dependent Protein S, Endostatin, Alpha-1-acid glycoprotein 1, Retinol binding protein 4, and Hemopexin were removed from product. 1/21/2020
Human CardiovascularMAP Fetuin-A and Vitamin K-Dependent Protein S were removed from product. 1/21/2020
Vitronectin Assay moved to a different multiplex. 1/15/2020
Insulin-like Growth Factor-Binding Protein 7 (IGFBP-7) Assay discontinued from human services. 1/15/2020
Sex Hormone Binding Globulin (SHBG) Assay discontinued from human services. 1/10/2020

2019

Assay or Product Description of Change Effective Date
Tectranectin Assay discontinued from human services. 12/26/2019
Macrophage-Stimulating Protein (MSP) Assay discontinued from human services. 12/26/2019
Gelsolin Assay discontinued from human services. 12/26/2019
Fibulin-1C (Fib-1C) Assay discontinued from human services. 12/26/2019
Interleukin-19 Simoa (IL-19 Simoa) Assay added to service offerings. 12/18/2019
Interleukin-4 Simoa (IL-4 Simoa) Assay added to service offerings. 11/26/2019
Dopamine beta-hydroxylase (DBH) Assay discontinued from human services. 10/4/2019
Immunoglobulin E (IgE) Assay discontinued from human services. 9/6/2019
Apolipoprotein B (Apo B) Assay added to service offerings. 8/8/2019
Uteroglobin Assay discontinued from human services. 8/7/2019
Interleukin-23 (IL-23) Assay discontinued from human services. 6/19/2019
Apolipoprotein E (Apo E) Assay discontinued from human services. 6/17/2019
Follicle-Stimulating Hormone (FSH) Assay adjusted to meet industry standards. 5/31/2019
Oncostatin-M Simoa (OSM Simoa) Assay added to service offerings. 5/6/2019
Oncostatin-M-specific receptor subunit beta Simoa (OSMR Simoa) Assay added to service offering. 5/6/2019
Tumor Necrosis Factor Ligand Superfamily Member 14 Total Simoa (LIGHT Total Simoa) Assay added to service offerings. 5/6/2019
Apolipoprotein B (Apo B) Assay discontinued from human services. 4/18/2019
Apolipoprotein(a) (Lp(a)) Assay was redeveloped using a new antigen. 3/7/2019
Tissue type Plasminogen activator (tPA) Assay was redeveloped using a new antigen. 1/11/2019
Urokinase-type Plasminogen Activator (uPA) Assay was redeveloped using a new antigen. 1/11/2019
Galectin-3 Assay does not meet performance specifications in EDTA plasma. 1/11/2019
E-Selectin Assay blocker formulation was adjusted. 1/10/2019
Monocyte Chemotactic Protein 2 (MCP-2) Assay blocker formulation was adjusted. 1/10/2019
Interleukin-6 receptor (IL-6r) Assay blocker formulation was adjusted. 1/10/2019
Monocyte Chemotactic Protein 4 (MCP-4) Assay blocker formulation was adjusted. 1/10/2019
Macrophage Inflammatory Protein-3 alpha (MIP-3 alpha) Assay blocker formulation was adjusted. 1/10/2019
Myeloid Progenitor Inhibitory Factor 1 (MPIF-1) Assay blocker formulation was adjusted. 1/10/2019
Monokine Induced by Gamma Interferon (MIG) Assay moved to a different multiplex. 1/10/2019
Interferon gamma Induced Protein 10 (IP-10) Assay moved to a different multiplex. 1/10/2019

2018

Assay or Product Description of Change Effective Date
Adiponectin Assay discontinued from human services. 12/13/2018
Interleukin-13 Simoa (IL-13 Simoa) Assay added to service offerings. 12/7/2018
Interleukin-17C Simoa (IL-17C Simoa) Assay added to service offerings. 12/7/2018
Interleukin-8 (IL-8) Assay moved to a different multiplex. 11/29/2018
Cellular Fibronectin (cFIB) Assay discontinued from human services. 11/29/2018
Interleukin-9 Simoa (IL-9 Simoa) Assay added to service offerings. 11/26/2018
Receptor Activator of Nuclear Factor Kappa B Ligand Simoa (RANKL Simoa) Assay added to service offerings. 11/14/2018
Tumor Necrosis Factor Ligand Superfamily Member 14 Simoa (LIGHT, free Simoa) Assay added to service offerings. 11/14/2018
Interleukin-8 Simoa (IL-8 Simoa) Assay added to service offerings. 10/16/2018
Interleukin-8 (IL-8) Assay moved to a different multiplex. 10/11/2018
Thymus-Expressed Chemokine (TECK) Assay was redeveloped using a new antigen. 9/14/2018
Apolipoprotein D (Apo D) Assay redeveloped with new capture and detection antibodies. 8/23/2018
Interleukin-18 binding protein (IL-18bp) Assay redeveloped with a new antigen. 8/15/2018
Osteocalcin Assay meets performance specifications in EDTA plasma. 8/2/2018
ST2 Assay meets performance specifications in Serum. 8/2/2018
CD163 Assay redeveloped with new antigen. 8/2/2018
CD163 Assay discontinued from human services. 7/3/2018
Osteocalcin Assay does not meet performance specifications in EDTA plasma. 7/3/2018
ST2 Assay does not meet performance specifications in Serum. 7/3/2018
Transforming Growth Factor beta-3 (TGF-beta 3) Assay discontinued from human services. 4/4/2018
Vaspin Assay was redeveloped using a new capture antibody. 3/20/2018
Omentin Assay does not meets performance specifications in Serum. 3/20/2018
Cartilage Oligomeric Matrix Protein (COMP) Assay added to human services. 3/9/2018
Alpha-1-Microglobulin (A1Micro, urine) Assay discontinued from human services. 3/6/2018
Tamm-Horsfall Urinary Glycoprotein (THP, urine) Assay discontinued from human services. 3/6/2018
Trefoil Factor 3 (TFF3, urine) Assay discontinued from human services. 3/6/2018
Interferon-alpha (IFN-alpha) Assay redeveloped with new capture and detection antibodies. 2/21/2018
CD27 antigen (CD27) Assay redeveloped with a new antigen. 2/6/2018
CD27 antigen (CD27) Assay blocker formulation was adjusted. 2/6/2018
Fibroblast Growth Factor 21 (FGF-21) Assay blocker formulation was adjusted. 2/6/2018
Fibroblast growth factor 23 (FGF-23) Assay blocker formulation was adjusted. 2/6/2018
Insulin-like Growth Factor-Binding Protein 7 (IGFBP-7) Assay blocker formulation was adjusted. 2/6/2018
Interleukin-1 receptor type 1 IL-1RI Assay blocker formulation was adjusted. 2/6/2018
Progranulin Assay blocker formulation was adjusted. 2/6/2018
Thymus-Expressed Chemokine (TECK) Assay blocker formulation was adjusted. 2/6/2018
Thymus-Expressed Chemokine (TECK) Assay blocker formulation was adjusted. 2/6/2018
Tissue Inhibitor of Metalloproteinases 3 (TIMP-3) Assay blocker formulation was adjusted. 2/6/2018
Interleukin-18-binding protein (IL-18bp) Assay discontinued from human services. 1/26/2018
Angiopoietin-1 (ANG-1) Assay meets performance specifications in EDTA plasma. 1/25/2018
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) Assay meets performance specifications in serum. 1/25/2018
Serum Amyloid A Protein (SAA) Assay meets performance specifications in serum. 1/19/2018
Ficolin-3 Assay redeveloped using a new capture antibody. 1/19/2018
Neutrophil Activating Peptide 2 (NAP-2) Assay redeveloped using a new capture antibody. 1/19/2018
Serum Amyloid A Protein (SAA) Assay redeveloped using new capture and detection antibodies. 1/19/2018

2017

Assay or Product Description of Change Effective Date
Amphiregulin (AR) Assay blocker formulation was adjusted. 11/6/2017
Epidermal Growth Factor (EGF) Assay blocker formulation was adjusted. 11/6/2017
Epidermal Growth Factor Receptor (EGFR) Assay blocker formulation was adjusted. 11/6/2017
Epiregulin (EPR) Assay blocker formulation was adjusted. 11/6/2017
Heparin-Binding EGF-Like Growth Factor (HB-EGF) Assay blocker formulation was adjusted. 11/6/2017
Placenta Growth Factor (PLGF) Assay blocker formulation was adjusted. 11/6/2017
Platelet-Derived Growth Factor BB (PDGF-BB) Assay blocker formulation was adjusted. 11/6/2017
Tenascin-C (TN-C) Assay blocker formulation was adjusted. 11/6/2017
Growth/differential factor 11 Simoa (GDF-11) Assay added to human services. 8/30/2017
Neurofilament Light Chain Simoa (NF-L) Assay added to human services. 8/24/2017
TruCulture OptiMAP™ v. 1.0 Product added to human services. 8/23/2017
Serum Amyloid P-Component (SAP) Assay moved to a different multiplex. 6/22/2017
CD40 Antigen (CD40) Assay added to human services. 6/8/2017
Macrophage Migration Inhibitory Factor (MIF) Assay redeveloped with a new antigen. 6/6/2017
Kidney Injury Molecule-1 Simoa (KIM-1) Assay added to human services. 5/30/2017
Immunoglobulin E (IgE) Assay added to human services. 5/25/2017
Amphiregulin Simoa (AR) Assay added to human services. 5/18/2017
Apolipoprotein B (Apo B) Assay added to human services. 5/17/2017
HE4 Assay adjusted to meet industry standards. 4/24/2017
Apolipoprotein B (Apo B) Assay discontinued from all human services. 4/17/2017
Adiponectin Assay added to human services. 4/13/2017
Interleukin-31 Simoa (IL-31) Assay added to human services. 4/13/2017
Human OncologyMAP v. 3.0 Product discontinued from human services. 4/3/2017
Adiponectin Assay discontinued from all human services. 4/3/2017
Serotransferrin (Transferrin) Assay added to human services. 4/3/2017
Monocyte Chemotactic Protein (MCP-4) Assay adjusted to meet industry standards. 4/3/2017
Osteocalcin Assay added to human services. 2/10/2017
Immunoglobulin E (IgE) Assay discontinued from all human services. 1/24/2017
Interferon-alpha Simoa (IFN-a) Assay added to human services. 1/23/2017
Aldose Reductase Assay discontinued from all human services. 1/12/2017
Glutathione S-Transferase Mu 1 (GST-M1) Assay discontinued from all human services. 1/12/2017
Peroxiredoxin-4 (Prx-IV) Assay discontinued from all human services. 1/12/2017
Phosphoserine Aminotransferase (PSAT) Assay discontinued from all human services. 1/12/2017
Lactoylglutathione lyase (LGL) Assay discontinued from all human services. 1/12/2017
Squamous Cell Carcinoma Antigen-1 (SSCA-1) Assay discontinued from all human services. 1/12/2017
Vascular Endothelial Growth Factor Receptor 3 (VEGFR-3) Assay added to human services. 1/9/2017

2016

Assay or Product Description of Change Effective Date
Mesothelin (MSLN) Assay discontinued from all human services. 12/21/2016
Growth/differentiation factor 11 (GDF-11) Assay discontinued from all human services. 12/13/2016
Hepatocyte Growth Factor (HGF) Assay added to human services. 11/4/2016
Beta-microseminoprotein (PSP94) Assay discontinued from all human services. 10/21/2016
Cystatin-A Assay discontinued from all human services. 10/21/2016
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) Assay discontinued from all human services. 10/21/2016
Cathepsin B (pro) (CTSB) Assay discontinued from all human services. 10/21/2016
Tenascin-X (TN-X) Assay discontinued from all human services. 10/21/2016
Lipocalin-1 (LCN1) Assay discontinued from all human services. 10/21/2016
Prostate Specific Antigen, total (tPSA) Assay discontinued from all human services. 10/21/2016
Interleukin-4 (IL-4) Assay added to human services. 10/10/2016
Fibulin-1C (Fib-1C) Assay redeveloped using a new standard. 10/6/2016
Interleukin-4 (IL-4) Assay discontinued from all human services. 9/8/2016
Ceruloplasmin Assay discontinued from all human services. 9/1/2016
Granulocyte Colony-Stimulating Factor Simoa (G-CSF) Assay added to human services. 8/26/2016
Interleukin-12 Subunit p40 Simoa (IL-12p40) Assay added to human services. 8/16/2016
Dipeptidyl peptidase IV (DPPIV) Assay discontinued from all human services. 8/12/2016
Monokine Induced by Gamma Interferon (MIG) Assay added to human services. 7/26/2016
Collagen IV Assay redeveloped using a new detection antibody. 7/1/2016
Immunoglobulin E (IgE) Assay redeveloped using a new antigen. 6/28/2016
Periostin Assay redeveloped using a new antibody pair. 6/23/2016
P-Selectin Assay does not meets performance specifications in EDTA plasma. 6/23/2016
Osteocalcin Assay discontinued from all human services. 6/23/2016
Urokinase-type Plasminogen Activator (uPA) Assay meets performance specifications in EDTA plasma. 6/17/2016
Secreted protein acidic and rich in cysteine (SPARC) Assay discontinued from human services. 5/9/2016
Interleukin-4 (IL-4) Assay added to human services. 5/6/2016
Serum Amyloid P-Component (SAP) Assay added to human services. 4/15/2016
Chromogranin-A (CgA) Assay blocker formulation was adjusted. 4/7/2016
Nerve Growth Factor beta (NGF-beta) Assay blocker formulation was adjusted. 4/7/2016
Neuronal Cell Adhesion Molecule (Nr-CAM) Assay blocker formulation was adjusted. 4/7/2016
S100 calcium-binding protein B (S100-B) Assay blocker formulation was adjusted. 4/7/2016
Sortilin Assay blocker formulation was adjusted. 4/7/2016
Receptor for advanced glycosylation end products (RAGE) Assay blocker formulation was adjusted. 4/7/2016
Superoxide Dismutase 1, soluble (SOD-1) Assay blocker formulation was adjusted. 4/7/2016
Interleukin-4 (IL-4) Assay temporarily discontinued from all human services. 3/22/2016
Monokine Induced by Gamma Interferon (MIG) Assay temporarily discontinued from all human services. 3/14/2016
Vascular Endothelial Growth Factor Receptor 3 (VEGFR-3) Assay discontinued from all human services. 3/1/2016
Hepatocyte Growth Factor (HGF) Assay discontinued from all human services. 3/1/2016
Urokinase-type plasminogen activator receptor (uPar) Assay redeveloped using a new antibody pair. 2/26/2016
Serum Amyloid P Component (SAP) Assay discontinued from all human services. 2/26/2016
Secreted protein acidic and rich in cysteine (SPARC) Assay meets performance specifications in EDTA plasma. 2/16/2016
Vascular endothelial growth factor D (VEGF-D) Assay redeveloped using a new antibody part number. 2/16/2016
C-Reactive Assay discontinued from all rodent services. 2/1/2016
Fibrinogen Assay discontinued from all rodent services. 2/1/2016
Serum Amyloid P-Component Assay discontinued from all rodent services. 2/1/2016
Osteocalcin Assay redeveloped using new antigen. 1/26/2016
Interleukin-2 Simoa (IL-2) Assay added to human services. 1/26/2016
Insulin-like Growth Factor-Binding Protein 3 Assay discontinued from human services. 1/13/2016
Insulin-like Growth Factor-Binding Protein 4 Assay discontinued from human services. 1/13/2016
Insulin-like Growth Factor-Binding Protein 5 Assay discontinued from human services. 1/13/2016
Insulin-like Growth Factor-Binding Protein 6 Assay discontinued from human services. 1/13/2016
A disintegrin and metalloproteinase with thrombospondin motifs 8 Assay added to human services. 1/11/2016
Folate receptor gamma Assay added to human services. 1/11/2016
Growth/differentiation factor 11 Assay added to human services. 1/11/2016
Aggrecan core protein Assay added to human services. 1/11/2016
C-C motif chemokine Assay added to human services. 1/11/2016
Uteroglobin Assay added to human services. 1/11/2016

2015

Assay or Product Description of Change Effective Date
CD40 antigen Assay discontinued from human services. 12/16/2015
Vitronectin Assay added to human services. 12/16/2015
Serotransferrin Assay discontinued from human services. 12/15/2015
Pentraxin-3 Assay discontinued from human services. 12/11/2015
Glycogen phosphorylase isoenzyme BB Assay added to human services. 12/11/2015
Interleukin-13 Assay redeveloped using new antigen. 12/7/2015
Alpha-1-Antichymotrypsin Assay discontinued from all human services. 11/30/2015
Apolipoprotein A-IV Assay discontinued from all human services. 11/30/2015
Heat Shock Protein 60 Assay discontinued from all human services. 11/30/2015
Proinsulin, intact Assay discontinued from all human services. 11/30/2015
Proinsulin, total Assay discontinued from all human services. 11/30/2015
Fibroblast Growth Factor-basic Assay discontinued from all human services. 11/30/2015
Cartilage Oligomeric Matrix Protein Assay discontinued from all human services. 11/30/2015
Complement component C1q receptor Assay discontinued from all human services. 11/30/2015
Chemerin Assay discontinued from all human services. 11/30/2015
Selenoprotein P Assay discontinued from all human services. 11/30/2015
Angiopoietin-related protein 3 Assay discontinued from all human services. 11/30/2015
Peptidase D Assay discontinued from all human services. 11/30/2015
Thrombospondin-4 Assay discontinued from all human services. 11/30/2015
Interleukin-5 Simoa (IL-5) Assay added to human services. 10/27/2015
Thyroglobulin Assay redeveloped using a new capture and detection antibody. 10/23/2015
Peroxiredoxin-4 Assay added to human services. 10/15/2015
Tissue Inhibitor of Metalloproteinases 1 Assay discontinued from human services (urine products only). 10/15/2015
B Lymphocyte Chemoattractant Simoa (BLC Simoa) Assay added to human services. 8/14/2015
Angiopoietin-related protein 4 Assay added to human services. 7/23/2015
Bone morphogenetic protein 9 Assay added to human services. 7/23/2015
Sclerostin Assay added to human services. 7/23/2015
Secreted protein acidic and rich in cysteine Assay added to human services. 7/23/2015
Midkine Assay discontinued from all human services. 7/17/2015
Glycogen phosphorylase isoenzyme BB Assay discontinued from all human services. 6/17/2015
Complement C3 (C3) Assay discontinued from all human services. 6/17/2015
Peroxiredoxin-4 Assay discontinued from all human services. 6/17/2015
Apolipoprotein A-I Assay added to human services. 6/11/2015
Vascular Endothelial Growth Factor C (VEGF-C) Assay discontinued from all human or mouse services. 6/11/2015
Sex Hormone-Binding Globulin (SHBG) Assay moved to a different multiplex. 4/29/2015
Leucine-Rich Alpha-2-Glycoprotein (LRG1) Assay discontinued from all human services. 4/29/2015
Serum Amyloid A Protein (SAA) Assay did not meet performance specifications in serum and results should be used for information purposes only. 4/17/2015
Alpha-2-Macroglobulin (A2M) Assay meets performance specifications in plasma EDTA. 4/15/2015
Interferon Gamma Simoa (IGN-g) Assay added to human services. 4/6/2015
Interleukin-1 beta Simoa (IL-1 b) Assay added to human services. 3/31/2015
Interleukin-10 Simoa (IL-10) Assay added to human services. 3/31/2015
Clusterin Assay redeveloped using new antigen. 3/20/2015
Creatine Kinase (CK-MB) Assay discontinued from human services. 3/19/2015
GLP-1 active Assay discontinued from human services. 3/12/2015
Insulin Assay added to human services. 3/12/2015
Lumican Assay discontinued from human services. 3/6/2015
Tumor Necrosis Factor-alpha (TNF-α) Assay added to human services. 3/4/2015
Interleukin-6 Simoa (IL-6) Assay added to human services. 3/4/2015
Cadherin-13 (T-cad) Assay added to human services. 2/24/2015
Midkine Assay added to human services. 2/24/2015
ApopotosisMAP 1.0 Product discontinued from human services. 2/18/2015
Insulin Assay discontinued from all human services. 2/11/2015
Peroxiredoxin-4 (Prx-IV) Assay added to human services. 2/9/2015
Protein S100-A6 (S100-A6) Assay added to human services. 2/9/2015
Glucose-6-phosphate Isomerase (G6PI) Assay moved to a different multiplex 2/9/2015
Lactoylglutathione lyase (LGL) Assay moved to a different multiplex 2/9/2015
Squamous Cell Carcinoma Antigen-1 (SCCA-1) Assay moved to a different multiplex 2/9/2015
Phosphoserine Aminotransferase (PSAT) Assay moved to a different multiplex 2/9/2015
Glutathione S-Transferase Mu 1 (GST-M1) Assay moved to a different multiplex 2/9/2015
Epithelial cell adhesion molecule (EpCam) Assay moved to a different multiplex 2/9/2015
Aldose Reductase Assay moved to a different multiplex 2/9/2015
Protein S100-A4 (S100-A4) Assay discontinued from all human services. 2/9/2015
DiscoveryMAP 175+ Product discontinued from human services. 2/3/2015
DiscoveryMAP 250+ Product discontinued from human services. 2/3/2015
ExplorerMAP Product added to human services. 2/3/2015
Complement C3 (C3) Assay discontinued from all human services 12/29/2015

2014

Assay or Product Description of Change Effective Date
Glutathione S-Transferase alpha (GST-alpha) Assay discontinued from all human services 11/24/2014
Secreted Protein Acidic and Rich in Cysteine (SPARC) Assay did not meet performance specifications in plasma and results should be used for information purposes only. 11/11/2014
RANTES Assay discontinued from all rodent services. 10/16/2014
Vitronectin Assay discontinued from all human services. 10/15/2014
Beta Amyloid1-40 (AB 40) Assay adjusted to meet industry standards. 10/8/2014
Beta Amyloid 1-42 (AB-42) Assay adjusted to meet industry standards. 10/8/2014
Lymphotactin Assay discontinued from all rodent services. 10/7/2014
Lipocalin-1 (LCN-1) Assay added to human services 10/7/2014
PYY Assay discontinued from all human services. 9/23/2014
Antithrombin-III Assay added to CardiovascularMAP 9/5/2014
Ficolin-3 Assay added to CardiovascularMAP 9/5/2014
Neurpilin-1 Assay added to CardiovascularMAP 9/5/2014
Neutrophil Activating Peptide 2 Assay added to CardiovascularMAP 9/5/2014
Pigment Epithelium Derived Factor Assay added to CardiovascularMAP 9/5/2014
Serum Amyloid A Protein Assay added to CardiovascularMAP 9/5/2014
Thrombin-Activatable Fibrinolysis Assay added to CardiovascularMAP 9/5/2014
Osteopontin Assay removed from CardiovascularMAP 9/5/2014
Glucagon Assay discontinued from all human services 9/5/2014
Receptor tyrosine-protein kinase erbB-3 Assay did not meet specifications in EDTA plasma 9/5/2014
Fatty Acid-Binding Protein, adipocyte Assay did not meet specifications in serum 9/5/2014
Galectin-3 Assay redeveloped using new antibody pair 9/5/2014
All human products Assay ranges updated 8/28/2014
Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Multiplex buffer composition adjusted. 8/27/2014
Interferon gamma (IFN-gamma) Multiplex buffer composition adjusted. 8/27/2014
Interleukin-10 (IL-10) Multiplex buffer composition adjusted. 8/27/2014
Interleukin-18 (IL-18) Multiplex buffer composition adjusted. 8/27/2014
Interleukin-2 (IL-2) Multiplex buffer composition adjusted. 8/27/2014
Interleukin-3 (IL-3) Multiplex buffer composition adjusted. 8/27/2014
Interleukin-4 (IL-4) Multiplex buffer composition adjusted. 8/27/2014
Interleukin-5 (IL-5) Multiplex buffer composition adjusted. 8/27/2014
Interleukin-6 (IL-6) Multiplex buffer composition adjusted. 8/27/2014
Interleukin-7 (IL-7) Multiplex buffer composition adjusted. 8/27/2014
Interleukin-8 (IL-8) Multiplex buffer composition adjusted. 8/27/2014
Macrophage Inflammatory Protein-1 alpha (MIP-1 alpha) Multiplex buffer composition adjusted. 8/27/2014
Macrophage Inflammatory Protein-1 beta (MIP-1 beta) Multiplex buffer composition adjusted. 8/27/2014
Monocyte Chemotactic Protein 1 (MCP-1) Multiplex buffer composition adjusted. 8/27/2014
Tumor Necrosis Factor alpha (TNF-alpha) Multiplex buffer composition adjusted. 8/27/2014
Tumor Necrosis Factor beta (TNF-beta) Multiplex buffer composition adjusted. 8/27/2014
Human NeuroMAP™ v. 1.0 Product added to human services 8/8/2014
Alpha-Fetoprotein (AFP) Assay adjusted to meet industry standards. 8/8/2014
Cortisol Assay adjusted to meet industry standards. 8/6/2014
CD 40 antigen (CD40) Multiplex buffer composition adjusted. 8/4/2014
CD40 Ligand (CD40-L) Multiplex buffer composition adjusted. 8/4/2014
Erythropoietin (EPO) Assay added to human services 8/4/2014
Myeloperoxidase (MPO) Assay moved to a different multiplex. 8/4/2014
Granulocyte Colony-Stimulating Factor (G-CSF) Multiplex buffer composition adjusted. 8/4/2014
Cancer Antigen 125 (CA 125) Assay adjusted to meet industry standards. 8/4/2014
Antithrombin-III (AT-III) Multiplex buffer composition adjusted. 8/4/2014
Ficolin-3 Multiplex buffer composition adjusted. 8/4/2014
Leucine-rich alpha-2-glycoprotein (LRG1) Multiplex buffer composition adjusted. 8/4/2014
Neutrophil Activating Peptide 2 (NAP-2) Multiplex buffer composition adjusted. 8/4/2014
Pigment Epithelium Derived Factor (PEDF) Multiplex buffer composition adjusted. 8/4/2014
Serum Amyloid A Protein (SAP) Multiplex buffer composition adjusted. 8/4/2014
Thrombin-activable fibrinolysis inhibitor (TAFI) Multiplex buffer composition adjusted. 8/4/2014
Neuropilin-1 Assay moved to a different multiplex. 8/4/2014
CD40 Assay discontinued from all rodent services 6/27/2014
Myeloperoxidase (MPO) Assay discontinued from all rodent services 6/27/2014
CD40 Ligand (CD40-L) Assay discontinued from all rodent services 6/27/2014
Complement Factor H Related Protein 1 (CFHR1) Assay moved to a different multiplex 6/20/2014
Complement Factor H Related Protein 1 (CFHR1) Assay removed from Human DiscoveryMAP 175+, Human DiscoveryMAP 250+ 6/20/2014
Canine KidneyMAP Product removed from rodent services 6/5/2014
Rat MetabolicMAP Product removed from rodent services 6/5/2014
Apolipoprotein C-I (Apo C-I) Assay added to CardiovascularMAP 5/6/2014
Chromogranin-A (CgA) Assay added to CardiovascularMAP 5/6/2014
Factor VII Assay added to CardiovascularMAP 5/6/2014
Fetuin-A Assay added to CardiovascularMAP 5/6/2014
Glucagon-like Peptide 1, active (GLP-1 active) Assay added to CardiovascularMAP 5/6/2014
Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Assay added to CardiovascularMAP 5/6/2014
Insulin Assay added to CardiovascularMAP 5/6/2014
Interferon gamma (IFN-gamma) Assay added to CardiovascularMAP 5/6/2014
Interferon gamma Induced Protein 10 (IP-10) Assay added to CardiovascularMAP 5/6/2014
Interleukin-1 alpha (IL-1 alpha) Assay added to CardiovascularMAP 5/6/2014
Interleukin-1 beta (IL-1 beta) Assay added to CardiovascularMAP 5/6/2014
Interleukin-6 receptor (IL-6r) Assay added to CardiovascularMAP 5/6/2014
Interleukin-10 (IL-10) Assay added to CardiovascularMAP 5/6/2014
Matrix Metalloproteinase-9 (MMP-9) Assay added to CardiovascularMAP 5/6/2014
Serotransferrin (Transferrin) Assay added to CardiovascularMAP 5/6/2014
Vascular Endothelial Growth Factor (VEGF) Assay added to CardiovascularMAP 5/6/2014
Vitamin K-Dependent Protein S (VKDPS) Assay added to CardiovascularMAP 5/6/2014
Adiponectin Assay added to OncologyMAP 5/6/2014
Alpha-2-Macroglobulin (A2Macro) Assay added to OncologyMAP 5/6/2014
Angiopoietin-2 (ANG-2) Assay added to OncologyMAP 5/6/2014
AXL Receptor Tyrosine Kinase (AXL) Assay added to OncologyMAP 5/6/2014
Beta-2-Microglobulin (B2M) Assay added to OncologyMAP 5/6/2014
Ciliary Neurotrophic Factor (CNTF) Assay added to OncologyMAP 5/6/2014
Fas Ligand (FasL) Assay added to OncologyMAP 5/6/2014
FASLG Receptor (FAS) Assay added to OncologyMAP 5/6/2014
Ferritin (FRTN) Assay added to OncologyMAP 5/6/2014
Fibroblast Growth Factor 4 (FGF-4) Assay added to OncologyMAP 5/6/2014
Insulin Assay added to OncologyMAP 5/6/2014
Interleukin-6 receptor (IL-6r) Assay added to OncologyMAP 5/6/2014
Monocyte Chemotactic Protein 3 (MCP-3) Assay added to OncologyMAP 5/6/2014
Plasminogen Activator Inhibitor 1 (PAI-1) Assay added to OncologyMAP 5/6/2014
Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) Assay added to OncologyMAP 5/6/2014
TNF-Related Apoptosis-Inducing Ligand Receptor 3 (TRAIL-R3) Assay added to OncologyMAP 5/6/2014
Transforming Growth Factor beta-3 (TGF-beta-3) Assay added to OncologyMAP 5/6/2014
Tumor necrosis factor receptor 2 (TNFR2) Assay added to OncologyMAP 5/6/2014
Vascular Cell Adhesion Molecule-1 (VCAM-1) Assay added to OncologyMAP 5/6/2014
Rat KidneyMAP v. 1.0 Product removed from rodent services 5/6/2014
Bio-Plex Pro™ RBM Rat Kidney Toxicity Service Product added to rodent services 5/6/2014
Factor VII Assay discontinued from all rodent products 5/6/2014
Adrenomedullin Assay added to human services 5/6/2014
Beta Amyloid 1-40 Assay added to human services 5/6/2014
Beta Amyloid 1-42 Assay added to human services 5/6/2014
Dopamine beta-hydroxylase Assay added to human services 5/6/2014
Heat-Shock protein 70 Assay added to human services 5/6/2014
Neurofilament heavy polypeptide Assay added to human services 5/6/2014
Protein DJ-1 Assay added to human services 5/6/2014
HE4 Assay redeveloped using new antibody pair. 5/1/2014
CA 72-4 Assay discontinued from all human products 4/3/2014
AACT Assay redeveloped using new antigen. 3/27/2014
Apolipoprotein A4 Assay redeveloped using new antigen. 3/27/2014
HSP60 Assay redeveloped using new antigen. 3/27/2014
Proinsulin (Total) Assay redeveloped using new antigen. 3/27/2014
Proinsulin (Intact) Assay redeveloped using new antigen. 3/27/2014
Midkine Assay discontinued from all human services. 3/27/2014
TIE-1 Assay discontinued from all human products. 3/20/2014
Urokinase-type Plasminogen Activator (uPA) This assay did not meet performance specifications in EDTA-plasma and results should be used for information purposes only. 3/10/2014
Lipocalin 1 (LCN1) Assay discontinued from all human products. 2/28/2014
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) Assay redeveloped using new antibody pair. 2/28/2014
tPA Assay redeveloped using new antibody pair. 2/28/2014
Pulmonary and Activation-Regulated Chemokine Assay moved to a different multiplex. 1/24/2014
Matrix Metalloproteinase-2 (MMP2) Assay moved to a different multiplex. 1/24/2014
EN-RAGE Assay moved to a different multiplex and now meets performance specifications in both serum and EDTA-plasma. 1/24/2014
MHC class I chain-related protein A (MICA) Assay moved to a different multiplex. 1/23/2014
Apolipoprotein B (Apo B) Multiplex buffer composition adjusted. 1/14/2014
CD5 Antigen-like (CD5L) Multiplex buffer composition adjusted. 1/14/2014
Clusterin (CLU) Assay dilution adjusted. 1/14/2014
Complement factor H-related protein 1 (CFHR1) Multiplex buffer composition adjusted. 1/14/2014
Fetuin A Multiplex buffer composition adjusted. 1/14/2014
Growth-regulated protein alpha (GRO-alpha) Assay moved to a different multiplex. 1/14/2014
Leptin R Assay redeveloped using new antibody pair. 1/14/2014
Progranulin Assay moved to a different multiplex. 1/14/2014
Thrombin-activatable fibrinolysis inhibitor (TAFI ) Assay redeveloped using new antibody pair. 1/14/2014
Vitamin K-Dependent Protein S (VKDPS) Assay redeveloped using new antibody pair. Multiplex buffer composition adjusted. 1/14/2014
Beta-2-Microglobulin Assay moved to a different multiplex. 1/13/2014
CD27 antigen Assay added to human services. 1/13/2014
Clusterin Assay moved to a different multiplex. Assay dilution adjusted. 1/13/2014
Fibroblast Growth Factor 21 Assay added to human services. 1/13/2014
Fibroblast Growth Factor 23 Assay added to human services. 1/13/2014
Insulin-like Growth Receptor Type 1 Assay added to human services. 1/13/2014
Insulin-like Growth Receptor Type 2 Assay added to human services. 1/13/2014
Progranulin Assay added to human services. 1/13/2014
Thymus-Expressed Chemokine Assay added to human services. 1/13/2014
Tissue Inhibitor of Metalloproteinsases 3 Assay added to human services. 1/13/2014
Vitronectin Assay moved to a different multiplex. 1/13/2014
Angiotensinogen (AGT) Assay discontinued from all human products. 1/9/2014
Apolipoprotein D (Apo D) Assay redeveloped using new antibody pair. 1/7/2014

2013

Assay or Product Description of Change Effective Date
Tissue Inhibitor of Metalloproteinases 3 (TIMP-3) This assay did not meet performance specifications in Serum and results should be used for information purposes only. 12/5/2013
Ezrin Assay discontinued from all human products. 12/2/2013
Malondialdehyde-Modified Low-Density Lipoprotein (MDA-LDL) This assay did not meet performance specifications and has been discontinued. 11/19/2013
Pentraxin-3 (PTX3) This assay did not meet performance specifications in EDTA-Plasma and results should be used for information purposes only. 9/25/2013
Cadherin-1 (E-CAD) This assay did not meet performance specifications in Serum and results should be used for information purposes only. 4/26/2013
Pancreatic secretory trypsin inhibitor (TATI) This assay did not meet performance specifications in Serum and results should be used for information purposes only. 4/26/2013
Tyrosine kinase with Ig and EGF homology domains 1 (Tie-1) This assay did not meet performance specifications in EDTA-Plasma and results should be used for information purposes only. 4/26/2013
Alpha-2-Macroglobulin (A2M) This assay did not meet performance specifications in EDTA-Plasma and results should be used for information purposes only. 4/26/2013
S100 calcium-binding protein B (S-100B) This assay did not meet performance specifications in EDTA-Plasma and results should be used for information purposes only. 4/26/2013
E-selectin This assay did not meet performance specifications in EDTA-Plasma and results should be used for information purposes only. 4/26/2013
EN-RAGE This assay did not meet performance specifications in EDTA-Plasma and results should be used for information purposes only. 4/26/2013
Prostate Specific Antigen, total (human) Assay adjusted to meet industry standards. 2/14/2013
MMP-2 (human) Assay discontinued from all human products. 1/23/2013
Apo-A1 (human) Updated serum and plasma ranges. Assay adjusted to meet industry standards. 1/15/2013
NGAL (rodent) Redeveloped using new antibody pair. 1/15/2013
Angiotensinogen (human) Myriad RBM range under evaluation. 1/15/2013
MMP-1 (human) Myriad RBM range under evaluation. 1/15/2013
MMP-7 (human) Myriad RBM range under evaluation. 1/15/2013
MMP-10 (human) Myriad RBM range under evaluation. 1/15/2013
MMP-9, total (human) Myriad RBM range under evaluation. 1/15/2013
Peroxiredoxin-4 (human) Assay discontinued from all human products. 1/8/2013
Protein S100 A6 (human) Assay discontinued from all human products. 1/8/2013