Our growing understanding of protein interactions throughout the body is leading to the creation of biomarker pathways that demonstrate the convergence of seemingly disparate pathways. The study of complex disorders such as autism highlights this sort of approach (see link) and this macro-level, “forest before the trees” approach, opens up novel avenues of research. How valuable do you feel mapping these biomarker pathways will prove in understanding the etiology, choosing appropriate drug targets, or monitoring the therapy for diseases?
