Potential application areas: Acute and Chronic Kidney disease (AKI and CKD), drug-induced nephrotoxicity, diabetic nephropathy, etc.
Nephrotoxicity or acute kidney injury is a major problem in both the preclinical and clinical setting that results in the failure of candidate compounds throughout the drug-development cycle. Sensitive methods for early detection of drug-induced nephrotoxicity and the progression of chronic kidney disease are therefore of critical importance.
Below is a list of protein biomarkers in our menu that have demonstrated utility in identifying and characterizing kidney toxicity in the scientific literature. The products listed here may also contain biomarkers useful in kidney function and toxicity research.
Click or mouse over biomarkers for more information