Potential application areas: Lung cancer, breast cancer, colon cancer, pancreatic cancer, prostate cancer, leukemia, melanoma, etc.

Decades of investigation has revealed how a progressive series of mutations can cause disruptions of normal cell functions, eventually resulting in malignant tumors. As the disease advances, the levels of protein biomarkers in the blood fluctuate in response to both the cancer progression and response to treatment. Hundreds of biomarkers have been implicated in the biology of cancer and Rules-Based Medicine has assembled the largest available collection of quantitative immunoassays to identify cancer-related biomarker patterns for various aspects of oncology research.

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Below is a list of blood-based protein biomarkers in our menu that have demonstrated links to cancer in the scientific literature. The products listed here may also contain biomarkers useful in oncology research.

Click or mouse over biomarkers for more information

1. 6Ckine 2. Adiponectin
3. Adrenocorticotropic Hormone 4. Aldose Reductase
5. Alpha-Fetoprotein 6. Amphiregulin
7. Angiopoietin-1 8. Angiopoietin-2
9. Angiopoietin-related protein 3 10. Annexin A1
11. Antileukoproteinase 12. Apolipoprotein A-I
13. Apolipoprotein E 14. Apolipoprotein H
15. AXL Receptor Tyrosine Kinase 16. B cell-activating factor
17. B Lymphocyte Chemoattractant 18. Bcl-2-like protein 2
19. Beta-2-Microglobulin 20. Beta-microseminoprotein
21. Betacellulin 22. Bone Morphogenetic Protein 6
23. C-Peptide 24. C-Reactive Protein
25. Cadherin-1 26. Cadherin-13
27. Calcitonin 28. Cancer Antigen 125
29. Cancer Antigen 15-3 30. Cancer Antigen 19-9
31. Cancer Antigen 72-4 32. Carbonic anhydrase 9
33. Carcinoembryonic Antigen 34. Carcinoembryonic antigen-related cell adhesion molecule 1
35. Carcinoembryonic antigen-related cell adhesion molecule 6 36. Cartilage Oligomeric Matrix Protein
37. Cathepsin B (pro) 38. Cathepsin D
39. CD 40 antigen 40. CD163
41. CD40 Ligand 42. Cellular Fibronectin
43. Chromogranin-A 44. Collagen IV
45. Complement C1q Antibody 46. Complement component C1q receptor
47. Cystatin-A 48. Cystatin-B
49. Cystatin-C 50. Decorin
51. Dickkopf-related protein 1 52. Dipeptidyl peptidase IV
53. Endoglin 54. Endostatin
55. Endothelin-1 56. Eotaxin-2
57. Epidermal Growth Factor 58. Epidermal Growth Factor Receptor
59. Epiregulin 60. Epithelial cell adhesion molecule
61. Ezrin 62. Fatty Acid-Binding Protein, adipocyte
63. Fatty Acid-Binding Protein, liver 64. Ferritin
65. Fetuin-A 66. Fibroblast growth factor 23
67. Fibroblast Growth Factor basic 68. Fibulin-1
69. Fibulin-1C 70. Galanin
71. Galectin-3 72. Gelsolin
73. Glucagon 74. Glucagon-like Peptide 1, total
75. Glucose-6-phosphate Isomerase 76. Glutamate-Cysteine Ligase Regulatory subunit
77. Glutathione S-Transferase Mu 1 78. Growth-Regulated alpha protein
79. Growth/differentiation factor 15 80. HE4
81. Heat Shock Protein 60 82. Heat-Shock protein 70
83. Hemopexin 84. Heparin-Binding EGF-Like Growth Factor
85. Hepatocyte Growth Factor 86. Hepatocyte Growth Factor receptor
87. Hepsin 88. Human Chorionic Gonadotropin beta
89. Human Epidermal Growth Factor Receptor 2 90. Insulin
91. Insulin-like Growth Factor Binding Protein 4 92. Insulin-like Growth Factor Binding Protein 5
93. Insulin-like Growth Factor Binding Protein 6 94. Insulin-like Growth Factor I
95. Insulin-like Growth Factor-Binding Protein 1 96. Insulin-like Growth Factor-Binding Protein 2
97. Insulin-like Growth Factor-Binding Protein 3 98. Interferon gamma Induced Protein 10
99. Interferon-inducible T-cell alpha chemoattractant 100. Interleukin-1 beta
101. Interleukin-18-binding protein 102. Interleukin-2
103. Interleukin-2 receptor alpha 104. Interleukin-23
105. Interleukin-6 106. Interleukin-6 receptor
107. Interleukin-6 receptor subunit beta 108. Interleukin-7
109. Interleukin-8 110. Kallikrein 5
111. Kallikrein-7 112. Lactoferrin
113. Lactoylglutathione lyase 114. Latency-Associated Peptide of Transforming Growth Factor beta 1
115. Leptin 116. Leucine-rich alpha-2-glycoprotein
117. Lipocalin-1 118. Lumican
119. Macrophage inflammatory protein 3 beta 120. Macrophage Inflammatory Protein-1 alpha
121. Macrophage Migration Inhibitory Factor 122. Macrophage-Stimulating Protein
123. Maspin 124. Mast/stem cell growth factor receptor
125. Matrix Metalloproteinase-10 126. Matrix Metalloproteinase-2
127. Matrix Metalloproteinase-3 128. Mesothelin
129. Methylglyoxal 130. MHC class I chain-related protein A
131. Midkine 132. Monocyte Chemotactic Protein 1
133. Monocyte Chemotactic Protein 3 134. Monokine Induced by Gamma Interferon
135. Myoglobin 136. Nerve Growth Factor beta
137. Neural Cell Adhesion Molecule 1 138. Neuron-Specific Enolase
139. Neuropilin-1 140. Neutrophil Activating Peptide 2
141. Neutrophil Gelatinase-Associated Lipocalin 142. Nucleoside diphosphate kinase B
143. Oncostatin-M 144. Osteocalcin
145. Osteopontin 146. Osteoprotegerin
147. P-Selectin 148. Pancreatic Polypeptide
149. Pancreatic secretory trypsin inhibitor 150. Pepsinogen I
151. Peptidase D 152. Peptide YY
153. Periostin 154. Peroxiredoxin-4
155. Phosphoserine Aminotransferase 156. Pigment Epithelium Derived Factor
157. Placenta Growth Factor 158. Plasminogen Activator Inhibitor 1
159. Platelet endothelial cell adhesion molecule 160. Platelet-Derived Growth Factor BB
161. Progranulin 162. Prolactin
163. Prostasin 164. Prostate Specific Antigen, total
165. Prostate-Specific Antigen, Free 166. Prostatic Acid Phosphatase
167. Protein S100-A4 168. Protein S100-A6
169. Pulmonary surfactant-associated protein D 170. Receptor tyrosine-protein kinase erbB-3
171. Resistin 172. S100 calcium-binding protein B
173. Secreted frizzled-related protein 4 174. Serum Amyloid A Protein
175. Sex Hormone-Binding Globulin 176. Squamous Cell Carcinoma Antigen-1
177. Stromal Cell-Derived Factor-1 alpha 178. Tenascin-C
179. Tenascin-X 180. Tetranectin
181. Thrombospondin-1 182. Thrombospondin-4
183. Thyroglobulin 184. Thyroglobulin Antibody
185. Tissue Inhibitor of Metalloproteinases 2 186. Tissue type Plasminogen activator
187. TNF-Related Apoptosis-Inducing Ligand Receptor 3 188. Transforming Growth Factor alpha
189. Trefoil Factor 3 190. Tumor Necrosis Factor alpha
191. Tumor Necrosis Factor beta 192. Tumor necrosis factor ligand superfamily member 12
193. Tumor necrosis factor ligand superfamily member 13 194. Tumor necrosis factor receptor 2
195. Tumor Necrosis Factor Receptor I 196. Tyrosine kinase with Ig and EGF homology domains 1
197. Tyrosine kinase with Ig and EGF homology domains 2 198. Urokinase-type Plasminogen Activator
199. Urokinase-type plasminogen activator receptor 200. Vascular Cell Adhesion Molecule-1
201. Vascular Endothelial Growth Factor 202. Vascular endothelial growth factor B
203. Vascular Endothelial Growth Factor C 204. Vascular endothelial growth factor D
205. Vascular Endothelial Growth Factor Receptor 1 206. Vascular Endothelial Growth Factor Receptor 2
207. Vascular endothelial growth factor receptor 3 208. Vitamin D-Binding Protein
209. Vitronectin 210. YKL-40