VACCINE DEVELOPMENT WITH TRUCULTURE APPLICATION NOTE

Abstract

TruCulture® is a whole blood collection and culture system for immune monitoring of subjects in clinical trials.
Utilized in hundreds of clinical trials for a variety of applications, TruCulture also has applications for vaccine development, for example:

• Detect vaccine-dependent T cell activation (antigen recall)
• Early safety studies of vaccines and their individual components
• Profile the functional immune status of clinical trial participants
  
  

By incorporating specific antigens and or adjuvants, we can develop and manufacture custom TruCulture tubes for vaccine clinical studies. In addition to positive and negative control tubes for T cell activation, we have a suite of viral and microbial innate immune system stimulants.