The epidemic of obesity in America is staggering and the costs of treating the diseases associated with being overweight are increasing. The prevalence of pediatric Type-2 diabetes (T2D) is particularly troubling since there has been a marked increase in frequency. Early intervention can reverse or prevent some of the more serious side-effects of the disease but detection is critical. Here the researchers describe a study using a non-invasive collection of saliva and test for metabolic-related biomarker differences in children with T2D.