Angiopoietin-related protein 3 (ANGPTL3)

ANGPTL3 is a secreted glycoprotein structurally related to the angiopoietins; consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. ANGPTL3 is predominantly expressed in the liver and involved in regulating triglyceride metabolism by inhibiting lipolysis of triglyceride-rich lipoproteins. ANGPTL3 plays an important role in lipid metabolism and is also involved in angiogenesis.

Swiss-Prot Accession Number: Q9Y5C1

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This analyte is not currently part of Myriad RBM's testing menu.