Chemerin (Chemerin)

Chemerin, also known as the Retinoic acid receptor responder protein 2, is a novel chemoattractant protein secreted as an 18-kDa inactive pro-protein. Active chemerin is abundant in ascetic fluid from ovarian cancer patients and synovial fluid from patients with arthritis. Signaling by chemerin is mediated by the seven-transmembrane-spanning G protein-coupled receptor, chemokine like receptor-1 (CMKLR1), ChemR23, or chemerinR. Both chemerin and chemerinR mRNA expression dramatically increases during the differentiation of preadipocytes into adipocytes.

Swiss-Prot Accession Number: Q99969

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This analyte is not currently part of Myriad RBM's testing menu.