Pentraxin-3 (PTX3)

Pentraxin-3 (PTX3) is a member of a superfamily of acute phase reactants characterized by a pentameric structure. CRP and SAP are well-characterized short pentraxins which are produced in the liver in response to inflammatory mediators. Pentraxin 3 is a long pentraxin, released by a variety of cell types including macrophages, neutrophils, myeloid-derived mesangial cells, synovial cells, smooth muscle cells, alveolar epithelium, and glial cells. PTX3 is elevated in critically ill patients, with a gradient from systematic inflammatory response syndrome to septic shock, and in several other diseases.

Swiss-Prot Accession Number: P26022


 
Product Associations Product Associations

This analyte is not currently part of Myriad RBM's testing menu.

 
 
Therapy Indications
Inflammation and Immune Response
 
Myriad RBM Publications Publications
Proteomic biomarkers of cognitive impairment in obstructive sleep apnea syndrome (2018) Lal C, Hardiman G, Kumbhare S, Strange C Sleep and Breathing
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