Thymus and activation-regulated chemokine (TARC)

Thymus and activation-regulated chemokine (TARC; CCL17) is chemotactic for T-lymphocytes but not monocytes or granulocytes. It may play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. It is expressed at high levels in thymus and at low levels in the lung, colon, and small intestine. It binds to the chemokine receptors CCR4 and CCR8 and plays important roles in T-cell development in thymus as well as in trafficking and activation of mature T-cells.

Swiss-Prot Accession Number: Q92583


 
Therapy Indications
Cytokines/Chemokines
Inflammation and Immune Response
 
Myriad RBM Publications Publications
Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges (2015) O'Bryant SE, Listac S, Rissman RA, Edwards M, Zhang F, Hall J, Zetterberg H, Lovestone S, Gupta V, Graff-Radford N, Martins R, Jeromin A, Waring S, Oh E, King M, Baker L, Hampel H Alzheimers Dement (2015) 1-8
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