Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6)
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) is a member of the immunoglobulin superfamily and is one of seven members of the CEACAM subfamily. It can also be referred to as nonspecific cross-reacting antigen (NCA) or CD66c. CEACAM6 is primarily expressed by granulocytes, their precursors, and epithelia of some organs. CEACAM6 helps regulate cell adhesion and forms homotypic bonds or heterotypic bonds with CEACAM1, CEACAM5, and/or CEACAM8 during this process. CEACAM6 expression is known to be upregulated in pancreatic and colon adenocarcinomas. CEACAM6 also exhibits highly variable expression in acute lymphocytic leukemias.
Swiss-Prot Accession Number: P40199