Cystatin-B (Cystatin-B)

Cystatin-B belongs to the cystatin protein superfamily. It is an intracellular thiol proteinase inhibitor that binds papain, and cathepsins L, H, and B. Cystatin-B may play a role in cell protection from proteases that leak from lysosomes. Cystatin-B is widely distributed in many tissue and cell types. Genetic defects cause progressive myoclonic epilepsy type 1. Elevated levels of cystatin-B have been found in epithelial tissue of ovarian cancer patients.

Swiss-Prot Accession Number: P04080


 
Product Associations Product Associations

This analyte is not currently part of Myriad RBM's testing menu.

 
 
Therapy Indications
 
Myriad RBM Publications Publications
Quantifying the spatial clustering characteristics of radiographic emphysema explains variability in pulmonary function (2023) Brian E. Vestal, Debashis Ghosh, Ra?l San Jos? Est?par, Katerina Kechris, Nature
Circulating Biomarkers and Outcome from a Randomised Phase Ii Trial of Sunitinib Vs Everolimus for Patients with Metastatic Renal Cell Carcinoma (2016) Voss MH, Chen D, Marker M, Hakimi AA, Lee C-H, Hsieh JJ, Knox JJ, Voi M, Motzer RJ British Journal of Cancer