Fatty Acid-Binding Protein, liver (FABP, liver)

Fatty Acid-Binding Protein, liver (L-FABP), also known as FABP-1, is abundant in the liver cytoplasm, but is also expressed in several other sites including the intestine, pancreas, kidney, lung and stomach. Unlike the other members of the FABP family, L-FABP is able to bind two ligands simultaneously helping fulfill its role in fatty acid uptake, transport, and metabolism.

Swiss-Prot Accession Number: P07148


 
Therapy Indications
Cancer
Cardiac and Vascular Markers/Disease
Diabetes, Lipid and Carbohydrate Metabolism
 
Myriad RBM Publications Publications
Influence of Genetic Ancestry on Human Serum Proteome (2020) Sjaarda J, Gerstein HC, Kutalik Z, Mohammadi-Shemirani P, Pigeyre M, Hess S, Pare G The American Journal of Human Genetics
Assessment of Urine Proteomics in Type 1 Primary Hyperoxaluria*American Journal of Nephrology (2016) Brooks ER, Hoppe B, Milliner DS, Salido E, Rim J, Krevitt LM, Olson JB, Price HE, Vural G, Langman CB American Journal of Nephrology
Comparison of Plasma and Urine Biomarker Performance in Acute Kidney Injury (2015) Schley G, K?berle C, Manuilova E, Rutz S, Forster C, Weyand M, Formentini I, Kientsch-Engel R, Eckardt K-U, Willam C PLoS ONE
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