Peroxiredoxin-4 (Prx-IV)

Peroxiredoxin 4 (Prx-IV) serves as an antioxidant and is probably involved in redox regulation of the cell. It regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. Prx-IV is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules.

Swiss-Prot Accession Number: Q13162

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This analyte is not currently part of Myriad RBM's testing menu.

Therapy Indications