Matrix Metalloproteinase-10 (MMP-10)
Matrix Metalloproteinase-10 (MMP-10), also known as stromelysin 2, degrades proteoglycans and fibronectin. MMP-10 has been linked to cancer stem cell vitality and metastasis. MMP-10 is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes such as arthritis.
Swiss-Prot Accession Number: P09238
Product AssociationsThis analyte is not currently part of Myriad RBM's testing menu.
PublicationsTezepelumab Efficacy in Patients with Severe, Uncontrolled Asthma with Comorbid Nasal Polyps in NAVIGATOR (2023) Tanya M Laidlaw, Andrew Menzies-Gow, Scott Caveney, Joseph K Han, Nicole Journal of Asthma and Allergy
Investigating data-driven biological subtypes of sychiatric disorders using specification-curve analysis (2020) Beijers L, van Loo HM, Romeijn JW, Lamers F, Schoevers RA, Wardenaar KJ Psychological Medicine
Dendritic cell immunotherapy followed by cART interruption during HIV-1 infection induces plasma protein markers of cellular immunity and neutrophil recruitment (2018) van den Ham HJ, Cooper J, Tomasik J, Bahn S, Aerts J, Oseterhaus A, Gruters R, Andeweg A PLoS One
Networks of blood proteins in the neuroimmunology of schizophrenia (2018) Jeffries CD, Perkins DO, Fournier M, Do KQ, Cuenod M, Khadimallah I, Domenici E, Addington J, Bearden CE, Cadenhead KS, Cannon TD, Cornblatt BA, Mathalon DH, McGlashan TH, Seidman LJ, Tsuang M, Walker EF, Woods SW Transl Psychiatry
Variation in Serum Biomarkers with Sex and Female Hormonal Status: Implications for Clinical Tests (2016) Ramsey JM, Cooper JD, Penninx BWJH, Bahn S Scientific Reports
A Semi-Mechanism Approach Based on Mri and Proteomics for Prediction of Conversion from Mild Cognitive Impairment to Alzheimer?s Disease (2016) Liu H, Zhou X, Jiang H, He H, Liu X Scientific Reports
Serum Proteomic Profiling of Major Depressive Disorder (2015) Bot M, Chan MK, Jansen R, Lamers F, Vogelzangs N, Steiner J, Leweke FM, Rothermundt M, Cooper J, Bahn S, Penninx BWJH Translational Psychiatry
Serum protein profiling reveals baseline and pharmacodynamic biomarker signatures associated with clinical outcome in mCRC patients treated with chemotherapy ? cediranib. (2014) Pommier AJ, Shaw R, Spencer SK, Morgan SR, Hoff PM, Robertson JD, Barry ST, J?rgensmeier JM. British Journal of Cancer 2014 Aug 14. doi: 10.1038/bjc.2014.436. [Epub ahead of print]
Multivariate Protein Signatures of Pre-Clinical Alzheimer's Disease in the Alzheimer's Disease Neuroimaging Initiative (ADNI) Plasma Proteome Dataset (2012) Johnstone D, Milward EA, Berretta R, Moscato P PLoS One. 2012;7(4):e34341
Multiplexed Immunoassay Panel Identifies Novel CSF Biomarkers for Alzheimer's Disease Diagnosis and Prognosis (2011) Craig-Schapiro R, Kuhn M, Xiong C, Pickering EH, Liu J, Misko TP, Perrin RJ, Bales KR, Soares H, Fagan AM, Holtzman DM PLoS One. 2011 Apr 19;6(4):e18850
Matrix metalloproteinases during and outside of migraine attacks without aura. (2009) Ashina M, Tvedskov JF, Lipka K, Bilello J, Penkowa M, Olesen J Cephalalgia 30: 303-310.