Macrophage Inflammatory Protein-1 beta (MIP-1 beta)
Macrophage Inflammatory Protein-1 beta (MIP-1 beta, CCL4, MIP-1?) is one of two major factor MIP proteins produced by macrophages following their stimulation with bacterial endotoxins. Both proteins are involved in the cell activation of human granulocytes (neutrophils, eosinophils, and basophils) and appear to be involved in acute neutrophilic inflammation. Both forms of MIP-1 stimulate the production of reactive oxygen species in neutrophils and the release of lysosomal enzymes. They also induce the synthesis of other pro-inflammatory cytokines such as IL-1, IL-6 and TNF in fibroblasts and macrophages.
Swiss-Prot Accession Number: P13236
PublicationsInflammatory CSF profiles and longitudinal development of cognitive decline in sporadic and GBA-associated PD (2023) Stefanie Lerche, Milan Zimmermann, Benjamin Roeben, Isabel Wurster, , Franca Laura Fries, Christian Deuschle, Katharina Waniek, Ingolf Lachmann, Meike Jakobi, Thomas O. Joos, Thomas Knorpp, Nicole Schneiderhan-Marra and Kathrin Brockmann Nature
Antibody profiles in COVID-19 convalescent plasma prepared with amotosalen/UVA pathogen reduction treatment (2022) Bagri A, de Assis RR, Tsai CT, Simmons G, Mei ZW, Von Goetz M, Gatmaitan M, Stone M, Di Germanio C, Martinelli R, Darst O, Rioveros J, Robinson PV, Ward D, Ziman A, Settel D, Khan S, Busch MP, Felgner PL, Corash LM Transfusion
Peripheral lymphocyte signaling pathway deficiencies predict treatment response in first-onset drug-na?ve schizophrenia (2022) Santiago G. Lago, Jakub Tomasik, Geertje F. Rees, Nitin Rustogi, Javier Vazquez-Bourgon, Sergi Papiol, Paula Suarez-Pinilla, Benedicto Crespo-Facorro, Sabine Bahn Brain Behavior and Immunity
Utility of urinary cytokine levels as predictors of the immunogenicity and reactogenicity of AS01-adjuvanted hepatitis B vaccine in healthy adults (2022) Wivine Burny, Caroline Herve, Magalie Caubet, Juan Pablo Yazabal, Arnaud M Didierlaurent Vaccine
Childhood trauma and LPS-stimulated inflammation in adulthood: Results from the Netherlands Study of Depression and Anxiety (2022) Ricki M.de Koning, Erika Kuzminskaite, Christiaan H.Vinkers, Erik J. Giltay, Brenda W.J.H.Penninx Brain, Behavior, and Immunity
A Phase Ib Dose-finding Study of Panobinostat and Ruxolitinib in Myelofibrosis (2022) Claire Harrison Florian H. Heidel, Alessandro M. Vannucchi, Jean-Jacques Kiladjian, Amjad Hayat, Francesco Passamonti, Eibhlin Conneally, Thomas Kindler, Bruno Martino,9 Daniel B. Lipka, Tommaso Stefanelli, Pantelia Roussou,Davide Germano,Jacqueline Ewan, and Vincent Ribrag Hemasphere
Live enteroviruses, but not other viruses, detected in human pancreas at the onset of type 1 diabetes in the DiViD study (2022) Lars Krogvold, Angelo Genoni, Anna Puggioni, Daniela Campani, Sarah J. Richardson, Christine S. Flaxman, Bj?rn Edwin, Trond Buanes, Knut Dahl-J?rgensen & Antonio Toniolo Diabetologia
Autologous NK cells propagated and activated ex vivo decrease senescence markers in human PBMCs (2022) Nickolas Chelyapov, Toai T Nguyen, Rafael Gonzalez Biochemistry and Biophysics Reports
Ligand conjugate structure activity relationships and enhanced endosomal escape with a targeted polymer micelle in non-human primates (2021) Holland RJ, Lam K, Ye X, Martin AD, Wood MC, Palmer L, Fraser D, McClintock K, Majeski S, Jarosz A, Lee ACH, Thi EP, Judge A, Heyes J Molecular Therapy
Pretreatment with ibrutinib reduces cytokine secretion and limits the risk of obinutuzumab-induced infusion-related reactions in patients with CLL: analysis from the iLLUMINATE study (2021) Greil R, Tedeschi A, Moreno C, Anz B, Larratt L, Simkovic M, Gill D, Gribben JG, Flinn IW, Wang Z, Cheung LWK, Nguyen AN, Zhou C, Styles L, Demirkan F Annals of Hematology
Comparison of serum and urinary biomarker panels with albumin/creatinine ratio in the prediction of renal function decline in type 1 diabetes. (2020) Colombo M, McGurnaghan SJ, Blackbourn LAK, Dalton RN, Dunger D, Bell S, Petrie JR, Green F, MacRury S, McKnight JA, Chalmers J, Collier A, McKeigue PM, Colhoun HM, Scottish Diabetes Research Network (SDRN) Type 1 Bioresource Investigators Diabetologia
Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis. (2020) Herster F, Bittner Z, Archer NK, Dickhofer S, Eisel D, Eigenbrod T, Knorpp T, Schneiderhan-Marra N, Loffler MW, Kalbacher H, Vierbuchen T, Heine H, Miller LS, Hartl D, Freund L, Schakel K, Heister M, Ghoreschi K, Weber ANR Nature Communications
Dynamic Aspects of Associations in Coronary Artery Disease: From Intracoronary Imaging to Blood Biomarkers (2020) Buljubasic, N. Erasmus University Rotterdam
Association of occupational exposures with ex vivo functional immune response in workers handling carbon nanotubes and nanofibers (2020) Schubauer-Berigan MK, Dahm MM, Toennis CA, Sammons DL, Eye T, Kodali V, Zeidler-Erdely PC, Erdely A Nanotoxicology
Systematic investigation of polyurethane biomaterial surface roughness on human immune responses in vitro (2020) Segan S, Jakobi M, Khokhani P, Klimosch S, Billing F, Schneider M, Martin D, Metzger U, Biesemeier A, Xiong X, Mukherjee A, Steuer H BioMed Research International
Inhibition of cytokine signaling by ruxolitinib and implactions for COVID-19 treatment (2020) Yeleswaram S, Smith P, Burn T, Covington M, Juvekar A, Li Y, Squier P, Langmuir P Clinical Immunology
Immune transriptome of cells infected with enterovirus strains obtained from cases of type 1 diabetes (2020) Poma AM, Genoni A, Broccolo F, Denaro M, Pugliese A, Basolo F, Toniolo A Microorganisms
Rapid tumor vaccine using Toll-like receptor-activated ovarian cancer ascites monocytes (2020) Adams SF, Grimm AJ, Chiang CLL, Mookerjee A, Flies D, Jean S, McCann GA, Michaux J, Pak H, Huber F, Neal C, Dangaj D, Bassani-Sternberg M, Rusakiewicz S, Facciabene A, Coukos G, Gimotty PA, Kandalaft LE Journal for ImmunoTherapy of Cancer
Immune response profiling of patients with spondyloarthritis reveals signalling networks mediating TNF-blocker function in vivo (2020) Menegatti S, Guillemot V, Latis E, Yahia-Cherbal H, Mittermuller D, Rouilly V, Mascia E, Rosine N, Koturan S, Millot G, Leloup C, Duffy D, Gleizes A, Hacein-Bey-Abina S, Milieu interieur Consortium, Sellam J, Berenbaum F, Miceli C, Dougados M, Bianchi E, Rogge L Ann Rheum Dis
Inflammatory parameters associated with systemic reactogenicity following vaccinatino with adjuvanted hepatitis B vaccines in humans (2019) Burny W, Marchant A, Herve C, Callegaro A, Caubet M, Fissette L, Gheyle L, Legrand C, Ndour C, Tavares Da Silva F, van der Most R, Willems F, Didierlaurent AM, Yarzabal J, ECR-008 study group Vaccine
Early changes in immune, coagulation, and organ function after clinical and experimental polytrauma (2019) Halbgbauer Repositorium der Universit?t Ulm
A new synthetic toll-like receptor 1/2 ligand is an efficient adjuvant for peptide vaccination in a human volunteer. (2019) Rammensee HG, Wiesmuller KH, Chandran PA, Zelba H, Rusch E, Gouttefangeas C, Kowalewski DJ, Di Marco M, Haen SP, Walz JS, Gloria YC, Bodder J, Schertel JM, Tunger A, Muller L, Kiebler M, Wehner R, Schmitz M, Jakobi M, Schneiderhan-Marra N, Klein R, Laske K, Artzner K, Backert L, Schuster H, Schwenck J, Weber ANR, Pichler BJ, Kneilling M, la Fougere C, Forchhammer S, Metzler G, Bauer J, Weide B, Schippert W, Stevanovic S, Loffler MW Journal for ImmunoTherapy of Cancer
Dendritic cell immunotherapy followed by cART interruption during HIV-1 infection induces plasma protein markers of cellular immunity and neutrophil recruitment (2018) van den Ham HJ, Cooper J, Tomasik J, Bahn S, Aerts J, Oseterhaus A, Gruters R, Andeweg A PLoS One
Phase Ib Study of Glasdegib, A Hedgehog Pathway Inhibitor, in (2018) Savona M, Pollyea D, Stock W, Oehler V, Schroeder MA, Lancet J, McCloskey J, Kantarigian H, Ma WW, Shaik MN, Laird AD, Zeremski M, O'Connell A, Chan G, Cortes JE Clinical Cancer Research
Association between IL-6 production in synovial explants from rheumatoid arthritis patients and clinical and imaging response to biologic treatment: A pilot study (2018) Andersen M, Boesen M, Ellegaard K, Soderstrom K, Soe NH, Spee P, Morch UGW, Torp-Pedersen S, Bartels EM, Danneskiold-Samsoe B, Karlsson L, Bliddal H Plos One
IL-17 blockade with secukinumab in peripheral spondyloarthritis impacts synovial immunopathology without compromising systemic immune responses (2018) van Mens LJJ, van de Sande MGH, Menegatti S, Chen S, Blijdorp ICP, de Jong HM, Fluri IA, Latuhihin TE, van Kuijk AWR, Rogge L, Yeremenko NG, Baeten DLP Arthritis Rheumatol
Synergistic Cytokine Effects as Apremilast Response Predictors in Patients With Psoriasis (2018) Garcet S, Nograles K, Correa da Rosa J, Schafer PH, Krueger JG Journal of Allergy and Clinical Immunology
Associations of 26 Circulating Inflammatory and Renal Biomarkers with Near-Infrared Spectroscopy and Long-term Cardiovascular Outcome in Patients Undergoing Coronary Angiography (ATHEROREMO-NIRS Substudy) (2018) Anroedh SS, Akkerhuis KM, Oemrawsingh RM, Garcia-Garcia HM, Brankovic M, Regar E, van Geuns RJ, Serruys PW, Daemen J, Van Mieghem NM, Boersma E, Kardys I Current Atherosclerosis Reports
Phase I study of BNC105P, carboplatin and gemcitabine in partially platinum-sensitive ovarian cancer patients in first or second relapse (ANZGOG-1103) (2018) Lindemann K, Beale PJ, Rossi E, Goh JC, Vaughan MM, Tenney ME, Martyn JK, Sommeijer D, Iglesias JL, Kremmidiotis G, Simpson J, Doolin E, Lavranos TC, Veillard AS, Espinoza D, Stockler MR, Rischin D Cancer Chemotherapy and Pharmacology
Serum Apolipoprotein E and Other Inflammatory Markers Can Identify Non-Responding Patients to a Dendritic Cell Vaccine (2018) Leeman H, Kaminska E, Green D, Bodman-Smith M, Gravett A, Bodman-Smith K, Copier J, Coulton G, Fusi A, Dalgleish AG Translational Oncology
RNA-antimicrobial peptide complexes fuel a TLR- and NETosis-mediated inflammatory cycle of neutrophil activation in psoriasis (2018) Herster F, Bittner Z, Dickhoefer S, Eisel D, Eigenbrod T, Knorpp T, Schneiderhan-Marra N, Loeffler MW, Hartl D, Freund L, Schaekel K, Heiser M, Ghoreschi K, Weber ANR bioRxiv
Inflammatory profile discriminates clinical subtypes in LRRK2-associated Parkinson's disease (2017) Brockmann K, Schulte C, Schneiderhan-Marra N, Apel A, Pont-Sunyer C, Vilas D, Ruiz-Martinez J, Langkamp M, Corvol JC, Cormier F, Knorpp T, Joos TO, Bernard A, Gasser T, Marras C, Schule B, Aasly JO, Foroud T, Marti-Masso JF, Brice A, Tolosa E, Berg D, Maetzler W. Eur J Neurol
Protein Biomarker Druggability Profiling (2017) Mani S, Cannon D, Ohls R, Oprea T, Mathias S, Ballard K, Ursu O, Bologa C J Biomed Inform
Randomized clinical study of safety, pharmacokinetics, andpharmacodynamics of RIPK1 inhibitor GSK2982772 in healthyvolunteers (2017) Weisel K, Scott NE, Tompson DJ, Votta BJ, Madhavan S, Povey K, Wolstenholme A, Simeoni M, Rudo T, Richards-Peterson L, Sahota T, Wang JE, Lich J, Finger J, Verticelli A, Reilly M, Gough PJ, Harris PA, Bertin J, Wang M Pharmacol Res Perspect.
The role of anxious distress in immune dysregulation in patients with major depressive disorder. (2017) Gaspersz R, Lamers F, Wittenberg G, Beekman ATF, van Hemert AM, Schoevers RA, Penninx BWJH Transl Psychiatry
The impact of antiretroviral therapy on iron homeostasis and inflammation markers in HIV-infected patients with mild anemia. (2017) Quiros-Roldan E, Castelli F, Lanza P, Pezzoli C, Vezzoli M; Inflammation in HIV Study Group, Biasiotto G, Zanella I J Transl Med.
Noninvasive Transcutaneous Vagus Nerve Stimulation Decreases Whole Blood Culture-Derived Cytokines and Chemokines: A Randomized, Blinded, Healthy Control Pilot Trial (2016) Lerman I, Hauger R, Sorkin L, Proudfoot J, Davis B, Huang A, Lam K, Simon B, Baker DG Neuromodulation: Technology at the Neural Interface
Effects of Acute Endurance Exercise on Plasma Protein Profiles of Endurance-Trained and Untrained Individuals over Time (2016) Schild M, Eichner G, Beiter T, Zuegel M, Niess AM, Steinacker JM, Mooren FC Mediators of Inflammation
Altered Cerebrospinal Fluid Proteins in Smith?Lemli? (2016) Cologna SM, Shieh C, Toth CL, Cougnoux A, Burkert KR, Bianconi SE, Wassif CA, Porter FD American Journal of Medical Genetics Part A
Effects of Repeated Complement Activation Associated with Chronic Treatment of Cynomolgus Monkeys with 2'-O-Methoxyethyl Modified Antisense Oligonucleotide (2016) Shen L, Engelhardt JA, Hung G, Yee J, Kikkawa R, Matson J, Tayefeh B, Machemer T, Giclas PC, Henry SP Nucleic Acid Therapeutics
Inflammatory Profile in Lrrk2-Associated Prodromal and Clinical Pd (2016) Brockmann K, Apel A, Schulte C, Schneiderhan-Marra N, Pont-Sunyer C, Vilas D, Ruiz-Martinez J, Langkamp M, Corvol J-C, Cormier F, Knorpp T, Joos TO, Gasser T, Sch?le B, Aasly JO, Foroud T, Marti-Masso JF, Brice A, Tolosa E, Marras C, Berg D, Maetzler W Journal of Neuroinflammation
Cytokine Production Capacity in Depression and Anxiety (2016) Vogelzangs N, De Jonge P, Smit JH, Bahn S, Penninx BW Translational Psychiatry
Towards a Blood-Based Diagnostic Panel for Bipolar Disorder (2016) Haenisch F, Cooper JD, Reif A, Kittel-Schneider S, Steiner J, Leweke FM, Rothermundt M, Van Beveren NJM, Crespo-Facorro B, Niebuhr DW, Cowan DN, Weber NS, Yolken RH, Penninx BWJH, Bahn S Brain, Behavior, and Immunity
Variation in Serum Biomarkers with Sex and Female Hormonal Status: Implications for Clinical Tests (2016) Ramsey JM, Cooper JD, Penninx BWJH, Bahn S Scientific Reports
Characterizing the Inflammatory Response in Esophageal Mucosal Biopsies in Children with Eosinophilic Esophagitis (2016) Sayej WN, Menoret A, Maharjan AS, Fernandez M, Wang Z, Balarezo F, Hyams JS, Sylvester FA, Vella AT Clinical & Translational Immunology
Plasma proteomics in CML patients before and after initiation of tyrosine kinase inhibitor therapy reveals induced Th1 immunity and loss of angiogenic stimuli. (2016) S?derlund S, Christiansson L, Persson I, Hjorth-Hansen H, Richter J, Simonsson B, Mustjoki S, Olsson-Str?mberg U, Loskog A. Leuk Res
Selective p38a MAP kinase/MAPK14 inhibition in enzymatically-modified LDL-stimulated human monocytes: implications for atherosclerosis. (2016) Cheng F, Twardowski L, Fehr S, Aner C, Schaeffeler E, Joos T, Knorpp T, Dorweiler B, Laufer S, Schwab M, Torzewski M. FASEB J
Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans (2015) Saykin A, Shen L, Xiohui Y, Kim S, Kwangsik N, Risacher SL, Ramanan VK, Foroud T, Faber KM, Sarwar N, Minsie L, Xiaolan H, Soares HD, Potkin S, Thompson PM, Kauwe JSK, Kaddurah-Daouk R, Green RC, Toga AW, Weiner MW Alzheimer's & Dementia
Late Stage Cancer Patients Remain Highly Responsive to Immune Activation by the Selective TLR8 Agonist Motolimod (VTX-2337) (2015) Dietsch GN, Randall TD, Gottardo R, Northfelt DW, Ramanathan RK, Cohen PA, Manjarrez KL, Newkirk M, Bryan JK, Hershberg RM Clinical Cancer Research
Identification of plasma biomarker concentration changes resulting from the administration of the Vascular Disrupting Agent BNC105 across 3 clinical trials in mesothelioma, ovarian and renal cancer (2015) Kremmidiotis G, Leske A, Simpson J, Doolin E, Iglesias J AACR 2015
Phase I Trial of the Pan-Pi3k Inhibitor Pilaralisib (Sar245408/Xl147) in Patients with Chronic Lymphocytic Leukemia (Cll) or Relapsed/Refractory Lymphoma (2015) Brown JR, Davids MS, Rodon J, Abrisqueta P, Kasar SN, Lager J, Jiang J, Egile C, Awan FT American Association for Cancer Research
A Phase 1 Dose-Finding Study of the Novel Toll-like Receptor 8 Agonist VTX 2337 in Adult Subjects with Advanced Solid Tumors or Lymphoma (2014) Northfelt DW, Ramanathan RK, Cohen PA, Von Hoff DD, Weiss GJ, Dietsch GN, Manjarrez KL, Randall TD, Hershberg RM Clin Cancer Res. 2014 May 7
Synovial explant inflammatory mediator production corresponds to rheumatoid arthritis imaging hallmarks: a cross sectional study (2014) Andersen, M., Boesen, M., Ellegaard, K., Christensen, R., S?derstr?m, K., S?e, N., & Bliddal, H Arthritis Research & Therapy, 16(3), R107
Circulating chemokines in relation to coronary plaque characteristics on radiofrequency intravascular ultrasound and cardiovascular outcome. (2014) Cheng JM, Oemrawsingh RM, Akkerhuis KM, Garcia-Garcia HM, de Boer SP, Battes LC, Buljubasic N, Lenzen MJ, de Jaegere PP, van Geuns RJ, Serruys PW, Kardys I, Boersma E. Informa Healthcare Biomarkers 2014 Sep 8:1-9. [Epub ahead of print]
Biomarkers of Central Nervous System Inflammation in Infantile and Juvenile Gangliosidoses. (2014) Utz JR, Crutcher T, Schneider J, Sorgen P, Whitley CB. Mol Genet Metab. 2014 Dec 6. pii: S1096-7192(14)00376-X. doi: 10.1016/j.ymgme.2014.11.015. [Epub ahead of print]
Distinctive Colonic Mucosal Cytokine Signature in New-Onset, Untreated Pediatric Crohn Disease (2014) Sylvester FA, Draghi A, Menoret A, Fernandez ML, Wang Z, Vella AT Journal of Pediatric Gastroenterology and Nutrition
The effects of vitamin A on cells of innate immunity in vitro (2013) Wojtal K, Wolfram L, Frey-Wagner I, Lang S, Scharl M, Vavricka SR, Rogler G Toxicology in Vitro,
A phase II clinical trial of the Vascular Disrupting Agent BNC105P as second line chemotherapy for advanced Malignant Pleural Mesothelioma (2013) Nowak AK, Brown C, Millward MJ, Creaney J, Byrne MJ, Hughes B, Kremmidiotis G, Bibby DC, Leske AF, Mitchell PL, Pavlakis N, Boyer M, Stockler MR Lung Cancer. 2013 Jun 17. pii: S0169-5002(13)00218-3
Biomarker identification in serum samples from patients with recurrent cervical cancer treated with ADXS11-001 immunotherapy (2013) Molli P, Malinina I, Wallecha A Journal for ImmunoTherapy of Cancer 2013, 1(Suppl 1):P61
Plasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status (2012) Pellis L, van Erk MJ, van Ommen B, Bakker GCM, Hendriks HFJ, Cnubben NHP, Kleemann R, van Someren EP, Bobeldijk I, Rubingh CM, Wopereis S Metabolomics
Identification of blood-based molecular signatures for prediction of response and relapse in schizophrenia patients (2012) Schwarz E, Guest PC, Steiner J, Bogerts B, Bahn S Translational Psychiatry (2012) 2, e82
Highly aggregated antibody therapeutics can enhance the in vitro innate and late-stage T-cell immune responses (2012) Joubert MK, Hokom M, Eakin C, Zhou L, Deshpande M, Baker MP, Goletz TJ, Kerwin BA, Chirmule N, Narhi LO, Jawa V J Biol Chem. 2012 Jul 20;287(30):25266-79
Expanding the Psoriasis Disease Profile: Interrogation of the Skin and Serum of Patients with Moderate-to-Severe Psoriasis (2012) Su?rez-Fari?as M, Li K, Fuentes-Duculan J, Hayden K, Brodmerkel C, Krueger JG J Invest Dermatol. 2012 Jul 5
A novel highly potent therapeutic antibody neutralizes multiple human chemokines and mimics viral immune modulation (2012) Scalley-Kim ML, Hess BW, Kelly RL, Krostag AR, Lustig KH, Marken JS, Ovendale PJ, Posey AR, Smolak PJ, Taylor JD, Wood CL, Bienvenue DL, Probst P, Salmon RA, Allison DS, Foy TM, Raport CJ PLoS One. 2012;7(8):e43332
Inflammatory profile and response to anti-TNF therapy in patients with chronic pulmonary sarcoidosis (2011) Loza MJ, Brodmerkel C, Du Bois RM, Judson MA, Costabel U, Drent M, Kavuru M, Flavin S, Lo KH, Barnathan ES, Baughman RP Clin Vaccine Immunol. 2011 Apr 20. [Epub ahead of print]
Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis (2011) Guglielmelli P, Barosi G, Rambaldi A, Marchioli R, Masciulli A, Tozzi L, Biamonte F, Bartalucci N, Gattoni E, Lupo ML, Finazzi G, Pancrazzi A, Antonioli E, Susini MC, Pieri L, Malevolti E, Usala E, Occhini U, Grossi A, Caglio S, Paratore S, Bosi A, Barbui T, Vannucchi AM Blood. 2011 Jul 1. [Epub ahead of print]
Treatment of experimental anterior and intermediate uveitis by a dexamethasone intravitreal implant (2011) Ghosn CR, Li Y, Orilla WC, Lin T, Wheeler L, Burke JA, Robinson MR, Whitcup SM Invest Ophthalmol Vis Sci. 2011 May 2;52(6):2917-23
Association of serum markers with improvement in clinical response measures after treatment with golimumab in patients with active rheumatoid arthritis despite receiving methotrexate: results from the GO-FORWARD study (2010) Visvanathan S, Rahman MU, Keystone E, Genovese M, Klareskog L, Hsia E, Mack M, Buchanan J, Elashoff M, Wagner C Arthritis Res Ther. 12:R211
Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis (2010) Verstovsek S, Kantarjian H, Mesa RA, Pardanani AD, Cortes-Franco J, Thomas DA, Estrov Z, Fridman JS, Bradley EC, Erickson-Viitanen S, Vaddi K, Levy R, Tefferi A N Engl J Med. 363: 1117-27.
Peripheral Blood Biomarkers Predict Disease Progression And Mortality In IPF (2010) Richards TJ, Lindell KO, Klesen M, Kaminski N, Zhang Y, Gibson KF Am J Respir Crit Care Me 181: A1120.
Human cytokine response to Texas crotaline envenomation before and after antivenom administration. (2010) Crocker P, Zad O, Milling T, Maxson T, King B, Whorton E Am J Emerg Med. 28: 871-9.
Classification of Alcohol Abuse by Plasma Protein Biomarkers. (2010) Freeman WM, Salzberg AC, Gonzales SW, Grant KA, Vrana KE Biol Psychiatry 68: 219-22.
Plasma Protein Profiling Reveals Protein Clusters Related to BMI and Insulin Levels in Middle-Aged Overweight Subjects (2010) van Dijk SJ, Feskens EJM, Heidema AG, Bos MB, van de Rest O, Geleijnse JM, de Groot LCPGM, Muller M, Afman LA PLoS ONE 12: e14422.
Molecular Analyte Profiling of the Early Events and Tissue Conditioning Following Intravesical Bacillus Calmette-Guerin Therapy in Patients With Superficial Bladder Cancer. (2009) Bisiaux A, Thiounn N, Timsit MO, Eladaoui A, Chang HH, Mapes J, Mogenet A, Bresson JL, Pri? D, B?chet S, Baron C, Sadorge C, Thomas S, Albert EB, Albert PS, Albert ML J Urol 181: 1571-1580.
Regression of Human Pancreatic Tumor Xenografts in Mice After a Single Systemic Injection of Recombinant Vaccinia Virus GLV-1h68. (2009) Yu YA, Galanis C, Woo Y, Chen N, Zhang Q, Fong Y, Szalay AA Mol Cancer Ther 8: 141-151.
Molecular Response to Cetuximab and Efficacy of Preoperative Cetuximab-Based Chemoradiation in Rectal Cancer. (2009) Debucquoy A, Haustermans K, Daemen A, Aydin S, Libbrecht L, Gevaert O, De Moor B, Tejpar S, McBride WH, Penninckx F, Scalliet P, Stroh C, Vlassak S, Sempoux C, Machiels JP J Clin Oncol 27: 2751-2757.
Pleural effects of indium phosphide in B6C3F1 mice: nonfibrous particulate induced pleural fibrosis (2009) Kirby PJ, Shines CJ, Taylor GJ, Bousquet RW, Price HC, Everitt JI, Morgan DL Exp Lung Res. 2009 Dec;35(10):858-82
Dexamethasone inhibits high glucose-, TNF-alpha-, and IL-1beta-induced secretion of inflammatory and angiogenic mediators from retinal microvascular pericytes. (2008) Nehm? A, Edelman J Invest Ophthalmol Vis Sci 49: 2030-2038.
Effects of the incubation in vitro with sorbents on serum proteomic pattern and cytokine concentration in cancer patients during chemotherapy--preliminary results. (2006) Piccolomini F, LouWratten M, Sereni L, Balestreri E, Donadio E, Felicioli A, Felicioli R, Donadio C Biomed Pharmacother 60: 463-467.