Interleukin-11 (IL-11)
Interleukin-11 (IL-11) is a cytokine, originating from bone marrow stroma and belonging to the IL-6 superfamily. IL-11 roles include the stimulation of B cells and megakaryocytes, modulation of antigen-antibody response, regulation of bone cell proliferation and differentiation, and induction of acute phase proteins. IL-11 may also be therapeutic to those suffering from osteoporosis.
Swiss-Prot Accession Number: P20809
Product AssociationsThis analyte is not currently part of Myriad RBM's testing menu.
PublicationsHigh false-positive rate of a putative biomarker test to aid in the diagnosis of schizophrenia (2016) Wehler CA, Preskorn, SH Journal of Clinical Psychiatry
Identification of Subgroups of Schizophrenia Patients with Changes in Either Immune or Growth Factor and Hormonal Pathways (2013) Schwarz E, Van Beveren NJM, Ramsey J, Leweke FM, Rothermundt M, Bogerts B, Steiner J, Guest PC, Bahn S Schizophrenia Bulletin
Validation of a Blood-Based Laboratory Test to Aid in the Confirmation of a Diagnosis of Schizophrenia (2010) Schwarz E, Izmailov R, Spain M, Barnes A, Mapes JP, Guest PC, Rahmoune H, Pietsch S, Leweke FM, Rothermundt M, Steiner J, Koethe D, Kranaster L, Ohrmann P, Suslow T, Levin Y, Bogerts B, (JM) van Beveren N, McAllister G, Weber N, Niebuhr D, Cowan D, Yolken RH, Bahn S Biomark Insights5: 39?47.