T Lymphocyte-Secreted Protein I-309 (I-309)
T Lymphocyte-Secreted Protein I-309 (I-309; CCL1), also known as small inducible cytokine A1, is a small glycoprotein secreted by activated T cells that belongs to a family of inflammatory cytokines known as chemokines. It is chemotactic for monocytes but not for neutrophils. CCL1 attracts monocytes, NK cells, immature B cells, and dendritic cells by interacting with a cell surface chemokine receptor called CCR8.
Swiss-Prot Accession Number: P22362
Dendritic cell immunotherapy followed by cART interruption during HIV-1 infection induces plasma protein markers of cellular immunity and neutrophil recruitment (2018) van den Ham HJ, Cooper J, Tomasik J, Bahn S, Aerts J, Oseterhaus A, Gruters R, Andeweg A PLoS One
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