Pharmacodynamic biomarkers for Apremilast treatment in psoriatic arthritis
A new paper from Peter Schafer, et al, of Celgene shows how biomarkers can be used to monitor treatment response in an inflammatory disease setting. T...
ENRAGE: A Novel Inflammatory Marker for Incident Coronary Heart Disease
This recent paper in the Arteriosclerosis, Thrombosis and Vascular Biology Journal of the American Heart Association describes an interesting prospect...
Blood-based proteins are crucial to the development of biomarker tests aimed at improving the diagnosis and treatment of psychiatric disorders
A recent review of studies measuring proteins in blood serum/plasma illustrates the systemic nature of disease-related changes in patients with schizo...
Biomarker signatures predict clinical outcomes in metastatic colorectal cancer (mCRC) patients treated with chemotherapy and cediranib
Researchers sought to explore biomarkers in pre- and on- treatment mCRC patients receiving chemotherapy with and without cediranib, in order to identi...
Vitamin D Binding Protein in serum demonstrates utility as a biomarker of Alzheimer’s disease
Researchers at the University of Texas Health Science Center, San Antonio used a Multiple Indicators Multiple Causes (MIMIC) approach to evaluate the...
Blood-based proteins help elucidate mediators of cognitive impairment in Late Life Depression (LLD)
Researchers from the University of Pittsburgh analyzed 242 proteins in conjunction with structural brain abnormalities to identify biological mechanis...
Biomarkers enhance prediction of cardiovascular events when added to clinical risk factors in the ORIGIN trial
Measuring large numbers of biomarkers in blood with new assay technologies may identify new biomarkers and physiologic pathways for cardiovascular eve...