Nephrotoxicity is a major problem in the preclinical and clinical setting that results in the failure of candidate compounds throughout the drug-development cycle. An article in this month’s GEN outlines the development of a new generation of biomarkers for drug-induced toxicity that provides greater sensitivity and earlier detection than previous methods.
https://www.genengnews.com/gen-articles/fighting-kidney-toxicity-the-case-for-better-biomarkers/5178/